Efficacy Testing of Collagen Drink on Skin Beauty and Sleep Aid

Sleep Disturbance Clinical Trial

Official title:

Efficacy Testing of Collagen Drink on Skin Beauty and Sleep Aid

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05182814
• Other study ID #: 21-102-B
• Status: Completed
• Phase: N/A
• Start date: November 10, 2021
• Est. completion date: April 30, 2022

Study information

• Verified date: March 2022
• Source: TCI Co., Ltd.
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

To assess Collagen Drink on skin condition and sleep quality improvement

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: April 30, 2022
• Est. primary completion date: February 28, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Healthy adults aged above 20 years old

Exclusion Criteria:

• Subject who is not willing to participate in this study.
• Patients with diseases of the skin, liver, kidney.
• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
• Female who is pregnant or nursing
• Constant drug use
• Received facial laser therapy, chemical peeling or UV overexposure (>3 hours everyday) in the past 4 weeks.
• Students taught by the PI

Related Conditions & MeSH terms

• Dyssomnias
• Parasomnias
• Skin Condition
• Skin Diseases
• Sleep Disturbance

Intervention

Dietary Supplement:
• Placebo drink
Blank
• Collagen Juice Drink
Testing product

Locations

Country	Name	City	State
Taiwan	Chia Nan University of Pharmacy & Science	Tainan

Sponsors (1)

Lead Sponsor	Collaborator
TCI Co., Ltd.

Country where clinical trial is conducted

Taiwan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The change of skin wrinkles	VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units	Change from Baseline skin wrinkles at 8 weeks
Primary	The change of skin texture	VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units	Change from Baseline skin texture at 8 weeks
Primary	The change of skin collagen density	DermaLab® Series SkinLab Combo was utilized to measure skin pores. Units: arbitrary units	Change from Baseline skin collagen density at 8 weeks
Primary	The change of skin elasticity	Cutometer® MPA580 was utilized to measure skin elasticity. Units: arbitrary units	Change from Baseline skin elasticity at 8 weeks
Primary	The change of skin L* value	Chroma Meter MM500 was utilized to measure skin L* value. Units: arbitrary units, 0-100	Change from Baseline L* value at 8 weeks
Primary	The change of sleep quality	Self-assessment questionnaire was utilized to survey sleep quality.	Change from Baseline sleep quality at 8 weeks
Primary	The change of AGEs of blood	Venous blood was sampled to measure AGEs	Change from Baseline AGEs at 8 weeks
Primary	The change of TIMP-1 of blood	Venous blood was sampled to measure TIMP-1	Change from Baseline TIMP-1 at 8 weeks
Primary	The change of desmosine of blood	Venous blood was sampled to measure desmosine	Change from Baseline desmosine at 8 weeks
Secondary	The change of skin melanin index	Soft Plus was utilized to measure skin melanin index. Units: arbitrary units	Change from Baseline skin melanin index at 8 weeks
Secondary	The change of skin pores	VISIA Complexion Analysis System was utilized to measure skin pores. Units: arbitrary units	Change from Baseline skin pores at 8 weeks
Secondary	The change of skin a* value	Chroma Meter MM500 was utilized to measure skin a* value. Units: arbitrary units	Change from Baseline skin a* value at 8 weeks
Secondary	The change of skin hydration	Corneometer® CM825 was utilized to measure skin hydration. Units: arbitrary Corneometer® units 0-120	Change from Baseline skin hydration at 8 weeks
Secondary	The change of transepidermal water loss	Tewameter® TM300 was utilized to measure skin hydration. Units: g/hm²	Change from Baseline transepidermal water loss at 8 weeks