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Sleep Disorders clinical trials

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NCT ID: NCT01067222 Completed - Sleep Disorders Clinical Trials

Efficacy and Safety Study of BF2.649 in the Treatment of Excessive Daytime Sleepiness in Narcolepsy

Harmony1
Start date: May 2009
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the efficacy and safety of BF2.649 administered by individual titration in narcoleptic patients with excessive daytime sleepiness (EDS)

NCT ID: NCT01064544 Completed - Sleep Problems Clinical Trials

Study on Hemodialysis: Illumination Effects

SHINE
Start date: March 2010
Phase: Phase 3
Study type: Interventional

Previous research has shown that sleep quality in hemodialysis patients is disturbed. One of the possible explanations is an insufficient or disturbed melatonin rhythm. Melatonin rhythm is regulated by exposure to light. In this feasibility study, the investigators examine the effects of light therapy during dialysis on sleep, melatonin rhythm and mood.

NCT ID: NCT01047930 Completed - Smoking Clinical Trials

The Effect of Exercise on Acute Nicotine Withdrawal

NicEx
Start date: January 2010
Phase: N/A
Study type: Interventional

The primary aim of this project is to test the effect of exercise on acute nicotine withdrawal. Acute nicotine withdrawal is characterized by a complex array of symptoms associated with increased risk of relapse among individuals attempting smoking cessation. The available remedies do not target all aspects of withdrawal. For example, pharmacologic treatments reduce withdrawal-based craving, but have no effect on cue-related craving, altered sleep, and mood disturbances during withdrawal. Therefore, non-pharmacologic behavioral techniques with the potential to attenuate persistent withdrawal symptoms are needed. We hypothesized that exercise can be a valid non-pharmacologic strategy to improve these domains.

NCT ID: NCT01030939 Completed - Sleep Disorders Clinical Trials

Study to Investigate Safety, Tolerability, Pharmacokinetics and Cardiac Function After Repeat Doses of SB-649868 in Healthy-volunteers

Start date: August 27, 2009
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine whether SB-649868 is safe, tolerable after repeated administrations in adult and elderly healthy volunteers. Pharmacokinetics and effects on cardiac function of repeated doses are studied

NCT ID: NCT01024192 Completed - Sleep Disorders Clinical Trials

Efficacy and Safety Assessment of ZOlpidem (Stilnox CR) in Patients With Chronic insomNIA

Start date: November 2009
Phase: Phase 4
Study type: Interventional

Primary Objective: To evaluate the efficacy and safety of the use of Stilnox CR in Mexican patients with chronic insomnia at the prescription conditions of daily practice Secondary Objective: To evaluate the satisfaction of the patient with chronic insomnia with Stilnox CR over an as needed basis.

NCT ID: NCT00994279 Completed - Breast Cancer Clinical Trials

Yoga or Educational Wellness Class for Women With Stage I, Stage II, or Stage III Breast Cancer Undergoing Chemotherapy

Start date: January 2010
Phase: N/A
Study type: Interventional

RATIONALE: Yoga and wellness classes may reduce fatigue and improve mood, sleep, and quality of life in women receiving chemotherapy for breast cancer. It is not yet known whether yoga is more effective than wellness education for women with breast cancer who are undergoing chemotherapy. PURPOSE: This randomized phase II trial is studying a community-based yoga class to see how well it works compared with an educational wellness class for women with stage I, stage II, or stage III breast cancer undergoing chemotherapy.

NCT ID: NCT00993850 Completed - Bipolar Disorder Clinical Trials

Sleep Disturbance and Bipolar Disorder

Start date: October 2009
Phase: Phase 3
Study type: Interventional

The study aims to evaluate a psychological intervention for individuals who suffer from sleep disturbance and bipolar disorder. We are hoping that this treatment will: (1) improve the quality of life of individuals with bipolar disorder who are suffering from sleep disturbance and (2) reduce the risk of, or help prevent, episodes.

NCT ID: NCT00992160 Completed - Sleep Disorders Clinical Trials

Vestipitant 28-day Tolerance Study

Start date: May 2009
Phase: Phase 2
Study type: Interventional

This study is a 28-day polysomnographic and subjective assessment of oral Vestipitant 15mg/day for treatment of Primary Insomnia in adults outpatients.

NCT ID: NCT00990106 Completed - Clinical trials for Stress Disorders, Post-Traumatic

Augmentation Trial of Prazosin for Post-Traumatic Stress Disorder (PTSD)

Start date: September 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether prazosin will: - reduce the incidence of nightmares and sleep disturbance - increase functioning and sense of well being in combat-trauma exposed Operation Iraqi Freedom/Operation Enduring Freedom (OIF/OEF) Veterans.

NCT ID: NCT00989976 Completed - Diabetes Clinical Trials

Individual Differences in Diabetes Risk: Role of Sleep Disturbances

Start date: February 2009
Phase: N/A
Study type: Interventional

The hypothesis for this study is that some individuals may be at much higher risk to develop type 2 diabetes and that the individual diabetes risk will be predicted by the individual level of slow wave sleep activity (SWA).