Sleep Disorders, Circadian Rhythm Clinical Trial
Official title:
Study of the Efficacy of Melatonin in the Burning Mouth Syndrome
Burning mouth ( BMS) syndrome is the oral disorder characterized by an intraoral burning
sensation for which no medical or dental cause can be found. The Headache Classification
Committee of the International Headache Society (IHS) defines (BMS) as an ''intraoral burning
or dysaesthetic sensation, recurring daily for more than 2 hours per day over more than 3
months, without clinically evident causative lesions''. (BMS) is a common, chronic problem
that has a negative impact on quality of life.
A wide variety of medications have been proposed for treating (BMS) both topical and
systemic. Unfortunately, no treatment seems to offer assured results. Melatonin is a
naturally occurring hormone secreted by the pineal gland. It has soporific effects with oral
administration and is well tolerated. It enhances sleep Melatonin also may help sleep
disturbances associated with (BMS) ; however, this remains to be proven.
The purpose of this study is to establish whether melatonin can aid in reducing pain improve sleep quality in (BMS) ;
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