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Sleep Apnea, Obstructive clinical trials

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NCT ID: NCT06041750 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Postoperative Pulmonary Complications In Obstructive Sleep Apnea Patients

Start date: October 15, 2023
Phase:
Study type: Observational [Patient Registry]

It is known that perioperative respiratory complications occur more often in obstructive sleep apnea syndrome (OSAS) patients during general anesthesia. Although there are prospective RCTs in this area, the need for further and larger studies remains due to the heterogenity of the results. Moreover, the incidence of postoperative pulmonary complications in OSAS patients undergoing surgery in Turkey and the predictive factors affecting the respiratory adverse events are uncertain. Therefore, in this prospective observational cohort study, it was aimed to determine the incidence of postoperative pulmonary complications and the predictor factors associated with patient, anesthesia and surgery in surgical patients with a confirmed or highly suspected OSAS diagnosis undergoing general anesthesia.

NCT ID: NCT06039865 Recruiting - Clinical trials for Obstructive Sleep Apnea

Chronic Care Management With Wearable Devices in Patients Prescribed Positive Airway Pressure Therapy (mPAP) Trial

mPAP
Start date: October 20, 2023
Phase: N/A
Study type: Interventional

The goal of this clinical trial in adults with obstructive sleep apnea prescribed positive airway pressure therapy is to test the effects of a new patient-facing consumer wearable-based program (that involves provision of a consumer wearable that measures oxygen levels during sleep plus customized weekly reports to participants). The main question is to learn whether participants' use of positive airway pressure therapy will differ between the participants who receive the new program immediately versus delayed. Participants assigned to the delayed program will receive usual care while waiting for the program to begin.

NCT ID: NCT06036329 Completed - Clinical trials for Obstructive Sleep Apnea

Whitsundays (Nasal) Mask Take Home Study (90 Days)

Start date: May 31, 2023
Phase: N/A
Study type: Interventional

The goal of this multi-site, prospective, randomized, double arm study without blinding is to test the usability of the Whitsundays mask system at home by patients with Obstructive Sleep Apnea. The main questions it aims to answer are: - How the Whitsundays masks performs in the home environment - What is the subject's first impression of the Whitsundays mask and what is their preference compared to their own mask - What is the difference between the subject's objective therapy data when using the Whitsundays mask compared to their own mask - Is there wear and tear of the Whitsundays mask and how frequently do the cushions need replacement Participants will be asked to use the Whitsundays mask for 90 days, answer questionnaires about the initial impression of the mask, the performance of the mask, and their preference compared to their own mask. Researchers will compare one group of subjects who will be provided with cushion replacements to another group who will only be provided with cushion replacements upon request to determine the need for cushion replacement, its frequency, and the reasons for cushion replacement during home usage.

NCT ID: NCT06030349 Recruiting - Quality of Life Clinical Trials

Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down Syndrome

REFRESHED
Start date: November 28, 2022
Phase:
Study type: Observational

The goal of this observational study is to learn about the use of non-invasive ventilation for treatment of obstructive sleep apnoea syndrome in children with Down Syndrome. The main questions it aims to answer are: - What is the impact of non-invasive ventilation on sleep behaviours and quality of life? - What barriers are faced by children and their families in establishing tolerance to non-invasive ventilation? Participants will be asked to complete questionnaires before and after starting treatment. Researchers will compare this data with the results of sleep studies and non-invasive ventilator downloads recorded as part of standard medical care. A sub-group of up to 20 participants will be invited to take part in 45-60 minute interviews exploring expectations, experiences and barriers encountered during non-invasive ventilation therapy.

NCT ID: NCT06029959 Recruiting - Clinical trials for Obstructive Sleep Apnea

Stroke and CPAP Outcome Study 3

SCOUTS3
Start date: September 28, 2023
Phase: N/A
Study type: Interventional

A problem with breathing during sleep, called obstructive sleep apnea (OSA), likely increases the risk of stroke and is common in people who have had a stroke, present in about 2/3 of stroke survivors. There is also evidence that OSA predicts worse outcome after stroke. The question being addressed in the Stroke and CPAP Outcome Study 3 (SCOUTS3) is how to improve use of continuous positive airway pressure (CPAP) therapy to treat OSA when started during intensive stroke rehabilitation.

NCT ID: NCT06027424 Completed - Clinical trials for The Effects of Obstructive Sleep Apnea on Blood Pressure Measurement

Blood Pressure and Obstructive Sleep Apnea

Start date: October 26, 2022
Phase:
Study type: Observational

Bidirectional and causal relationship exists between obstructive sleep apnea (OSA) and hypertension in a dose-response manner, independent of confounding variables such as age, smoking, and body mass index. OSA is conventionally diagnosed and graded by apnea-hypopnea index (AHI). The relationship between AHI and changes of blood pressure deserves further investigation.

NCT ID: NCT06023927 Not yet recruiting - Clinical trials for Obstructive Sleep Apnea

Obstructive Sleep Apnea as a Risk Factor for Normal Tension Glaucoma and a Crucial Step in Preventing Blindness

Start date: June 15, 2024
Phase:
Study type: Observational

The purpose of this research study is to learn more about the relationship between Obstructive Sleep Apnea (OSA) and Normal Tension Glaucoma (NTG). OSA is a nighttime disorder of the upper airway that causes an intermittent lack of oxygen while sleeping. NTG is a type of glaucoma that occurs despite the normal intraocular pressure levels, making its detection more difficult. Left untreated, irreversible optic nerve damage and extensive vision loss can result. Previous research has shown some evidence between OSA and the development of NTG. The investigators are researching whether undergoing treatment for OSA would help to improve the vascular health to the retina, and in effect, improve the early signs of visual dysfunction seen with diagnostic testing.

NCT ID: NCT06022133 Completed - Clinical trials for Obstructive Sleep Apnea of Adult

Sodium, Nocturnal Blood Pressure and Nocturnal Pauses in Breathing

ROSA
Start date: January 3, 2018
Phase: N/A
Study type: Interventional

A reduction of dietary sodium intake reduces blood pressure and risk of cardiovascular disease.

NCT ID: NCT06017921 Recruiting - Clinical trials for Obstructive Sleep Apnea

Effect of Eszopiclone on Adherence to CPAP and Severity of Insomnia in Patients With COMISA

Start date: August 24, 2023
Phase: Phase 4
Study type: Interventional

The comorbidity between obstructive sleep apnea (OSA) and insomnia (COMISA) is common, and associated with poorer sleep quality. CPAP adherence among COMISA patients is worst than among those with OSA only. The investigators will compare the effect of Eszopiclone 3mg or placebo for 14 days on adherence to CPAP after 30 days and after 6 months.

NCT ID: NCT06012526 Completed - Clinical trials for Obstructive Sleep Apnea-hypopnea

The Study of Sleep Disordered Breathing in Patients With Interstitial Lung Diseases

Start date: November 25, 2020
Phase:
Study type: Observational

This was a cross-sectional observational study to evaluate the prevalence and predictive factors of SDB in ILD and to analyze the relationship between polysomnography (PSG) findings, pulmonary function, disease severity, parenchymal involvement, and sleep questionnaires ESS and SBQ. This study included 69 patients who were diagnosed with diffuse parenchymal lung diseases by high-resolution computed tomography (HRCT) chest. All patients were subjected to clinical examination, HRCT, spirometry, full-night polysomnography, and echocardiography.