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Skin Diseases clinical trials

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NCT ID: NCT00574392 Completed - Melanoma Clinical Trials

Multi-Wavelength and Coherence Confocal Reflectance Microscopy of Pigmented and Non-Pigmented Lesions on the Skin In-Vivo

Start date: November 2006
Phase: N/A
Study type: Observational

The purpose of this study is to image skin and skin lesions with a new imaging technology called "multiwavelength and coherence confocal reflectance microscopy". This technology uses low intensity laser to image below the surface of the skin. This technology may provide a new way of looking at skin and skin lesions. The goal of this study is to evaluate the images of your skin taken by this microscope. The techniques being evaluated in this study use multi wavelength and coherence confocal reflectance microscopy invivo. The term "in vivo" means in/on a living subject. In this study you will be the living subject and the multi wave length and coherence confocal microscope will be placed on your skin to look at your skin lesions and your normal skin. The confocal microscope uses a weak laser light and a sophisticated lens to image the individual cells that make up the skin. Your lesion will be photographed with high resolution photography. An area near your skin lesion that is clinically normal will also be imaged in the same manner.

NCT ID: NCT00541931 Completed - Skin Diseases Clinical Trials

Pilot Investigation of a Multinutrient Supplement on Skin Aging and Aging Metabolites in Healthy Women

Start date: October 2007
Phase: N/A
Study type: Interventional

We are seeking healthy female volunteers to determine if multinutrient supplementation affects visible signs of skin aging as well as blood measurements of aging. We are seeking smokers and non-smokers.

NCT ID: NCT00488761 Completed - Clinical trials for Skin Diseases, Infectious

Study Evaluating the Safety and Efficacy of Tigecycline in Hospitalized Patients With cSSSI

Start date: July 2006
Phase: Phase 4
Study type: Interventional

Tigecycline's activity against resistant organisms, as well as significant coverage of both gram-positive and gram-negative bacteria, may provide a valuable therapeutic alternative in treating patients with complicated skin and/or skin structure infections.

NCT ID: NCT00488345 Completed - Clinical trials for Bacterial Infections

Study Evaluating the Pharmacokinetics (PK), Safety, and Tolerability of Tigecycline in Patients 8 to 11 Years of Age

Start date: December 2007
Phase: Phase 2
Study type: Interventional

To determine the pharmacokinetic profile and to evaluate the safety and tolerability of ascending multiple doses of tigecycline in patients aged 8 to 11 years with selected serious infections; complicated intra-abdominal infections (cIAI), complicated skin and skin structure infections (cSSSI), or community-acquired pneumonia (CAP).

NCT ID: NCT00488293 Completed - Quality of Life Clinical Trials

Impact of Teledermatology on Health Services Outcomes in the Department of Veterans Affairs

Start date: November 2008
Phase: N/A
Study type: Interventional

This study compares store and forward teledermatology with the conventional clinic-based consult process. Our primary objective is to determine whether the mean change in quality of life, as rated by the subscale scores and composite score on the Skindex-16 differs between the store and forward and conventional care modalities.

NCT ID: NCT00388310 Completed - Clinical trials for Skin Diseases, Infectious

Effective Antibiotic Treatment of MRSA

Start date: February 2006
Phase: N/A
Study type: Interventional

To evaluate the effective duration (in days) to clinical improvement of outpatient antibiotic regimens in the treatment of superficial abscesses caused by MRSA in patients that present to the emergency department.

NCT ID: NCT00368784 Completed - Psoriasis Clinical Trials

T Cell Repertoire Analysis of Immune Mediated Skin Diseases

Start date: January 2007
Phase:
Study type: Observational

This study is designed to identify the cells of the immune system that cause skin disease such as psoriasis and mycosis fungoides. Blood samples from many patients will be compared in hopes of finding common cells and molecules responsible for skin diseases. Results of this study will increase our knowledge about immune mediated skin disease.

NCT ID: NCT00368537 Completed - Clinical trials for Skin Diseases, Bacterial

Study Comparing the Safety and Efficacy of Tigecycline With Ampicillin-Sulbactam or Amoxicillin-Clavulanate to Treat Skin Infections

Start date: September 2006
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the safety and efficacy of the antibiotic tigecycline with other antibiotics, ampicillin-sulbactam, and amoxicillin-clavulanate in the treatment of a complicated skin and/or skin structure infection (cSSSI).

NCT ID: NCT00343135 Completed - Clinical trials for Skin Diseases, Infectious

AUGMENTIN 1gm In Skin And Soft Tissue Infection

Start date: December 2004
Phase: Phase 4
Study type: Interventional

Study to evaluate the effects of AUGMENTIN 1gm in the treatment of Skin and Soft tissue infections

NCT ID: NCT00341692 Completed - Neoplasms Clinical Trials

Studying Normal Breast Tissue and Cancer Risk

Start date: April 7, 2003
Phase:
Study type: Observational

Breast cancer is the most common cancer among women in the United States. Breast cancer research has been hampered by the difficulty in collecting normal breast tissue. In this study, researchers will obtain samples of normal breast tissue from organ donors and will collect risk-factor data from next-of-kin. The purpose of this study is to learn how normal breast develops and responds to stresses that are known to increase a woman s chance of developing breast cancer. Following the breast-tissue donation from 20 volunteers, surgical technicians will make small incisions in the skin and tissue of the breast and remove several samples measuring about one-inch. Technicians also will take samples of the uterine lining to estimate the date of the last menstrual period. The tissue will then be sent to the National Cancer Institute for laboratory research studies. Steps will be taken to ensure that the identity of the participants remains confidential.