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Skin Diseases, Bacterial clinical trials

View clinical trials related to Skin Diseases, Bacterial.

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NCT ID: NCT02925416 Completed - Clinical trials for Skin Diseases, Bacterial

Safety of Either a Single or Two Intravenous Doses of Orbactiv in Participants With Acute Bacterial Skin and Skin Structure Infection

Start date: January 24, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study was to evaluate the safety and tolerability of two 1200 milligram (mg) intravenous (IV) infusions of oritavancin when administered one week apart.

NCT ID: NCT02814916 Completed - Clinical trials for Bacterial Infections

Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children, Known or Suspected to be Caused by Susceptible Gram-positive Organisms, Including MRSA

Start date: March 31, 2017
Phase: Phase 3
Study type: Interventional

To determine the safety and descriptive efficacy of dalbavancin for the treatment of acute bacterial skin and skin structure infections in children, aged birth to 17 years (inclusive), known or suspected to be caused by susceptible Gram-positive organisms, including methicillin-resistant strains of Staphylococcus aureus.

NCT ID: NCT02570490 Completed - Clinical trials for Acute Bacterial Skin and Skin Structure Infections

Oral Sodium Fusidate (CEM-102) Versus Oral Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infections

Start date: November 2015
Phase: Phase 3
Study type: Interventional

Phase 3, randomized, double-blind, multi-center efficacy and safety study to evaluate an oral CEM-102 loading dose regimen compared to oral linezolid in the treatment of subjects with ABSSSI

NCT ID: NCT02477514 Completed - Clinical trials for Skin Diseases, Bacterial

A Study to Evaluate the Effects of Tedizolid Phosphate on the Pharmacokinetics and Safety of Midazolam and Rosuvastatin (MK-1986-004)

Start date: June 2015
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the effect of steady-state tedizolid phosphate on the single-dose pharmacokinetics of midazolam and rosuvastatin in healthy, adult participants.

NCT ID: NCT02452918 Completed - Clinical trials for Acute Bacterial Skin and Skin Structure Infection

A Study to Evaluate the Safety of a Single Intravenous (IV) Dose of Orbactiv (Oritavancin) in Participants on Chronic Warfarin Therapy Being Treated For Acute Bacterial Skin and Skin Structure Infection (ABSSSI)

Start date: September 29, 2015
Phase: Phase 4
Study type: Interventional

This was a Phase 4, multicenter, open-label safety study of a single 1200 milligrams (mg) IV infusion of oritavancin in adult participants on chronic warfarin with acute bacterial skin and skin structure infection (ABSSSI) suspected or proven to be caused by Gram-positive pathogens. An additional group of participants with ABSSSI, who were not on concomitant warfarin therapy, were also enrolled to obtain additional information following a single dose of oritavancin administration.

NCT ID: NCT02276482 Completed - Clinical trials for Skin Diseases, Infectious

Study of Tedizolid Phosphate in Adolescents With Complicated Skin and Soft Tissue Infection (cSSTI) (MK-1986-012)

Start date: March 25, 2015
Phase: Phase 3
Study type: Interventional

The purpose of the study is to compare the safety of intravenous (IV) and/or oral 6-day 200 mg tedizolid phosphate with 10-day comparator in participants 12 to <18 years with cSSTI.

NCT ID: NCT02269319 Completed - Clinical trials for Bacterial Infections

MRX-I Versus Linezolid for the Treatment of Acute Bacterial Skin and Skin Structure Infection

ABSSSI
Start date: February 2015
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether MRX-I is as safe and effective as Linezolid in the treatment of adult patients with acute bacterial skin and skin structure infections

NCT ID: NCT02024867 Completed - Abscess Clinical Trials

Evaluation of 3 Versus 10 Days of Antibiotics in Skin Abscesses After Surgical Drainage

Start date: February 2010
Phase: N/A
Study type: Interventional

The objective of this study is to determine if there is a difference in treatment failures and recurrent skin infections when patients are given 3 or 10 days of antibiotics for uncomplicated skin abscesses after they have been surgically drained.

NCT ID: NCT01700842 Completed - Clinical trials for Bacterial Skin Diseases

Multicenter Study of Antimicrobial Resistance of Gram-positive and Gram-negative Clinical Strains to Ceftaroline and Other Antimicrobials in Russia

CERBERUS
Start date: October 2012
Phase: N/A
Study type: Observational

Approximately 3,000 of clinically significant isolates of different species from respective respective sources in geographically distinct Russian cities will be collected and tested on ceftaroline and other antimicrobials.

NCT ID: NCT01119105 Completed - Infection Clinical Trials

Study Comparing the Safety and Efficacy of Two Doses of BC-3781 vs Vancomycin in Patients With Acute Bacterial Skin and Skin Structure Infection (ABSSSI)

Start date: May 2010
Phase: Phase 2
Study type: Interventional

This is a Phase II, multi-center, randomized, double-blind study comparing the safety and efficacy of two doses of BC-3781 versus vancomycin in patients with acute bacterial skin and skin structure infection.