Retreatment With Intratumoral Diffusing Alpha Radiation Emitters

Status Recruiting

Clinical Trial Summary

A unique approach for cancer treatment employing intratumoral diffusing alpha radiation emitter device for superficial cutaneous, mucosal or soft tissue neoplasia

Clinical Trial Description

This will be a prospective, open label, single arm, controlled study, assessing the safety and efficacy of re-treatment with diffusing alpha emitters radiation therapy (DaRT) delivered through radioactive seeds inserted into the tumor. This approach combines the advantages of local intratumoral irradiation of the tumor, as used in conventional brachytherapy, with the power of the alpha radiation emitting atoms, that will be introduced in quantities considerably lower than radiation therapy already used in patients. Superficial lesions with histopathological confirmation of either recurrent or persistent disease following DaRT treatment. . Reduction in tumor size 70 days after DaRT insertion will be assessed. Safety will be assessed by the incidence, severity and frequency of all Adverse Events (AE). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04540588
Study type	Interventional
Source	Alpha Tau Medical LTD.
Contact	Adi Cohen
Phone	+972-2-3737-212
Email	adic@alphatau.com
Status	Recruiting
Phase	N/A
Start date	December 22, 2020
Completion date	January 1, 2026

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