Survival and PN Dependence in SBS Patients

Short Bowel Syndrome Clinical Trial

Official title:

Long-term Survival and Parenteral Nutrition Dependence in Adult Patients With Non-malignant Short Bowel Syndrome

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06102668
• Other study ID #: FirstAHUSTChina
• Status: Completed
• Start date: January 1, 2012
• Est. completion date: January 1, 2019

Study information

• Verified date: October 2023
• Source: The First Affiliated Hospital of University of Science and Technology of China
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Short bowel syndrome (SBS) is a rare condition resulting from the loss of portions of the small intestine, and can cause a spectrum of metabolic and physiologic disturbances.The objective of this study was to determine the longterm survival and parenteral nutrition dependence of adult patients with SBS.

Description:

Short bowel syndrome (SBS), the most common form of intestinal failure, is a rare condition resulting from the loss of portions of the intestine, typically because of extensive surgical resection or loss of intestinal function. Patients with SBS often stuffer from intestinal insufficiency or intestinal failure because they are unable to maintain fluid and nutrient balances on a normal diet. SBS can cause various metabolic and physiologic disturbances. Although parenteral nutrition is a life-saving measure for many patients with SBS, patients with SBS is associated with decreased survival and parenteral nutrition (PN) dependence. Few studies have reported the survival and PN dependence in adult SBS patients in China.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 173
• Est. completion date: January 1, 2019
• Est. primary completion date: January 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 100 Years

Eligibility

Inclusion Criteria:

• Adult patients diagnosed with SBS.

Exclusion Criteria:

• age <18 years; patients with active malignant tumors.

Related Conditions & MeSH terms

• Short Bowel Syndrome
• Syndrome

Locations

Country	Name	City	State
n/a

Sponsors (2)

Lead Sponsor	Collaborator
The First Affiliated Hospital of University of Science and Technology of China	Jinling Hospital, China

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Survival	Survival rate in patients with SBS	2012/1/1-2019/1/1
Primary	Parenteral nutrition dependence	Parenteral nutrition dependence in patients with SBS	2012/1/1-2019/1/1
Secondary	Risk factors	Risk factors of mortality and parenteral dependence in patients with SBS	2012/1/1-2019/1/1
Secondary	Cause of death	Cause of death in patients with SBS at the end of follow-up	2012/1/1-2019/1/1