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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT06102668
Other study ID # FirstAHUSTChina
Secondary ID
Status Completed
Phase
First received
Last updated
Start date January 1, 2012
Est. completion date January 1, 2019

Study information

Verified date October 2023
Source The First Affiliated Hospital of University of Science and Technology of China
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Short bowel syndrome (SBS) is a rare condition resulting from the loss of portions of the small intestine, and can cause a spectrum of metabolic and physiologic disturbances.The objective of this study was to determine the longterm survival and parenteral nutrition dependence of adult patients with SBS.


Description:

Short bowel syndrome (SBS), the most common form of intestinal failure, is a rare condition resulting from the loss of portions of the intestine, typically because of extensive surgical resection or loss of intestinal function. Patients with SBS often stuffer from intestinal insufficiency or intestinal failure because they are unable to maintain fluid and nutrient balances on a normal diet. SBS can cause various metabolic and physiologic disturbances. Although parenteral nutrition is a life-saving measure for many patients with SBS, patients with SBS is associated with decreased survival and parenteral nutrition (PN) dependence. Few studies have reported the survival and PN dependence in adult SBS patients in China.


Recruitment information / eligibility

Status Completed
Enrollment 173
Est. completion date January 1, 2019
Est. primary completion date January 1, 2019
Accepts healthy volunteers No
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria: - Adult patients diagnosed with SBS. Exclusion Criteria: - age <18 years; patients with active malignant tumors.

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
n/a

Sponsors (2)

Lead Sponsor Collaborator
The First Affiliated Hospital of University of Science and Technology of China Jinling Hospital, China

Outcome

Type Measure Description Time frame Safety issue
Primary Survival Survival rate in patients with SBS 2012/1/1-2019/1/1
Primary Parenteral nutrition dependence Parenteral nutrition dependence in patients with SBS 2012/1/1-2019/1/1
Secondary Risk factors Risk factors of mortality and parenteral dependence in patients with SBS 2012/1/1-2019/1/1
Secondary Cause of death Cause of death in patients with SBS at the end of follow-up 2012/1/1-2019/1/1
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