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Severe Stroke clinical trials

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NCT ID: NCT05998902 Recruiting - Dysphagia Clinical Trials

Optimizing Early Nutrition Support in Severe Stroke-2

Start date: December 20, 2023
Phase: Phase 3
Study type: Interventional

Post stroke pneumonia (PSP) is one of the common early complications of stroke. Post-stroke infections, in general, are associated with less favorable neurologic outcomes. Aspiration is one of the most feared complications of enteral nutrition and can lead to the occurrence of pneumonia. Severe stroke patients are at high risk for aspiration due to some factors such as the reduced level of consciousness, inability to protect the airway and so on. The purpose of this study is to explore the ideal nutrition support strategy for patient with acute severe stroke to help reduce the incidence of PSP and improve the prognosis.

NCT ID: NCT04816201 Recruiting - Electroacupuncture Clinical Trials

Electroacupuncture to Assist Ventilator Weaning in Severe Stroke

Start date: April 1, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the efficacy of electroacupuncture in assisting ventilator weaning in patients with severe stroke

NCT ID: NCT03805009 Completed - Clinical trials for Cardiovascular Diseases

Efficacy of End-Effector Robot-Assisted Gait Training in Subacute Stroke Patients

Start date: March 19, 2013
Phase: N/A
Study type: Interventional

To date, no studies seems to compare conventional gait rehabilitation program with end-effector RAGT in subacute stroke patients by analysing the variations of gait kinematics beyond clinical multi prospective outcomes. The aim of this pilot study is to evaluate the efficacy of end-effector RAGT in subacute stroke patients in terms of clinical outcomes and gait kinematics, comparing them with conventional gait rehabilitation program.

NCT ID: NCT03395717 Completed - Clinical trials for Cardiovascular Diseases

Stroke Rehabilitation With Exoskeleton-assisted Gait.

EKSOGAIT
Start date: March 16, 2016
Phase: N/A
Study type: Interventional

Gait recovery is one of the main goals of post-stroke rehabilitation where robotic-assisted practice has shown positive outcomes. However, literature lacks of clinical studies on exoskeleton-supported gait rehabilitation. Recently, a wearable exoskeleton (Ekso™, EksoBionics, USA) has been commercialized for re-enabling patients to stand and walk, involving them directly in steps trigger through body weight balance. The main aim of this study is to assess the clinical and neuromuscular effects of exoskeleton-based gait rehabilitation in sub-acute and chronic stroke patients, compared to patients with similar characteristics who will conduct a traditional over-ground gait training. In this multicentric RCT, 162 stroke patients will be enrolled and randomly assigned to the Experimental Group (EG) or to the Control Group (CG). Patients will conduct at least 12 one-hour-sessions (about 3 times/ week) of Ekso™ (EG) or traditional over-ground (CG) gait rehabilitation. Clinical evaluations (lower limb Modified Ashworth Scale- MAS; Motricity Index - MI; Trunk Control Test - TCT; Functional Ambulation Classification - FAC; 10-meter walking test - 10mwt; 6-minute walking test - 6mwt; Walking Handicap Scale - WHS; Time Up and Go - TUG) will be administered to patients at the beginning (T1) and at the end (T2) of the training period. The primary outcome is the distance performed during the 6mwt. A follow up study at 1 month (T3) and at 3 months (T4) after T2 will be conducted.

NCT ID: NCT02982668 Terminated - Dysphagia Clinical Trials

Optimizing Early Enteral Nutrition in Severe Stroke

OPENS
Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this academic lead study is to explore the ideal nutritional support strategy for patient with acute severe stroke.

NCT ID: NCT02982655 Completed - Hypertension Clinical Trials

Controlling Hypertension After Severe Cerebrovascular Event

CHASE
Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this academic lead study is to explore ideal blood pressure targets and optimum individualized anti-hypertension strategies in acute severe stroke.