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Seroma clinical trials

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NCT ID: NCT04035590 Recruiting - Breast Cancer Clinical Trials

Seroma Reduction and Drain Free Mastectomy

SARA
Start date: June 26, 2020
Phase: N/A
Study type: Interventional

To prove that omitting drains after mastectomy and flap fixation does not contribute to higher incidence of seroma formation and therefore reducing patient disutility such as seroma aspirations and visits to the outpatient clinic, as well as reducing seroma related wound complications.

NCT ID: NCT03773575 Recruiting - Amputation Clinical Trials

Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications

PREVENA-AMP
Start date: January 15, 2019
Phase: N/A
Study type: Interventional

This study is a prospective, multi-center, two-arm, unblinded, and randomized controlled trial with a goal of evaluating the impact of a closed incision negative pressure dressing (PREVENA) on incidence of post-operative wound complications and medical costs in patients undergoing lower extremity amputation.

NCT ID: NCT03738527 Recruiting - Breast Cancer Clinical Trials

SEroma Reduction pOst MAstectomy "SEROMA Study"

SEROMA
Start date: October 7, 2019
Phase: Phase 4
Study type: Interventional

This is a pilot study to evaluate the feasibility of conducting a larger trial to determine if the use of intraoperative topical tranexamic acid (TXA) decreases the rate of post-operative hematomas and seromas in breast cancer patients after their mastectomy. In other words, the investigators want to determine if applying TXA inside the surgical wound before it is closed helps reduce blood or serous fluid accumulation at the operative site. Dependent on the results of this study, a further larger trial may or may not take place. Post-operative seromas and hematomas are common complications of mastectomy surgery not only leading to infection, discomfort, wound dehiscence or emergency room visits; they also delay in some instances post-operative adjuvant radiotherapy. Establishing whether or not topical TXA is an effective strategy to decrease those complications can potentially impact positively the breast cancer treatment. To achieve this aim, this randomized pilot study will first determine whether a larger multicenter study if feasible. This study will replicate a formal randomized trial at a smaller scale in a single center in order to assess the recruitment and randomization process, as well as provide preliminary results for our research question.

NCT ID: NCT03598712 Recruiting - Breast Cancer Clinical Trials

Local Compression Seroma DIminution Objective (CLODIS)

CLODIS
Start date: November 18, 2018
Phase: Phase 3
Study type: Interventional

This study evaluates the impact of local compression by chest bandage on the number of seroma punctures in patients treated by mastectomy with or without lymphadectomy. Half of the participants will have local compression by chest bandage in addition to seroma punctures while the other half will only have punctures.

NCT ID: NCT03190876 Recruiting - Clinical trials for Complication of Surgical Procedure

Seroma Prevention After Body Contouring Procedures

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

With a prevalence of up to 25%, seroma formation is among the most common complications of body contouring procedures such as abdominoplasty. Small amounts of fluid are reabsorbed by the body spontaneously, however, larger seroma volumes need to be evacuated via puncture aspiration to prevent wound healing disturbances and infection, leading to major patient discomfort and a prolonged hospital stay. There is increasing controversy regarding the efficacy of surgical drains in seroma prevention. This study compares the incidence rate of seroma in three study arms with different usage of drains.

NCT ID: NCT03167944 Recruiting - Seroma Clinical Trials

Traditional Electrosurgery System Versus Low Thermal Tissue Dissection System for Total Mastectomy

Start date: March 15, 2017
Phase: N/A
Study type: Interventional

Breast cancer is one of the most common cancer among women nowadays. There are lots of modality of treatment and one of them is Mastectomy. We found out that seroma is one of the disturbing postoperative complications after mastectomy. In our study we want to compare the outcome between using the conventional electrocautery and the low thermal tissue dissection. We expected that the serum production should be lower in cases using low thermal system electrosurgery system.

NCT ID: NCT01454167 Recruiting - Infections Clinical Trials

Acid Base and Electrolytes Patterns in Drains Operational Wounds and Its Relation to Complications

Start date: May 2014
Phase: N/A
Study type: Observational

Objective- The purpose of this study is to evaluate a connection between PH,PCO2,HCO3,PO2,Na,K,Glu and Lactate patterns in vacuum drains of different plastic operational wounds and its relation to infections and seroma formation.