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Seroma clinical trials

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NCT ID: NCT06389331 Completed - Hernia Clinical Trials

Study on Effects of Defect Closure in Laparoscopic Repair of Direct Inguinal Hernia

Start date: September 1, 2020
Phase:
Study type: Observational

The defect closure was found to have higher pain and less seroma formation at various intervals of time following TEP for moderate-large direct inguinal hernia. Although these findings were statistically insignificant, they may be clinically significant, and further studies with a larger sample size are suggested.

NCT ID: NCT05682209 Completed - Clinical trials for Seroma Following Procedure

The Effect of Octreotide on Wound Drainage After Mastectomy

Start date: December 18, 2020
Phase: Phase 4
Study type: Interventional

Patients who had mastectomy for breast cancer usually have drainage of some fluid from the site of surgery. This could be prolonged and may lead to other negative consequences after surgery. Octreotide could potentially reduce the amount of this drainage. In this study, patients were grouped into two: a first group that received octreotide injection and a second group that received a placebo. The study tested whether octreotide injection has any effect on the duration of fluid drainage from the surgery site after mastectomy for breast cancer.

NCT ID: NCT04730674 Completed - Clinical trials for Post-mastectomty Seroma

Predictive Factors Affecting the Efficacy of Local Tetracycline Injection for Treatment of Post-mastectomy Seroma.

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

female patients with established diagnosis of post-mastectomy seroma following modified radical mastectomy, were treated by local injection of tetracycline after the seroma fluid was aspirated, then a crepe bandage was applied over the mastectomy area. Then after 5 days the patient were examined again for seroma re-collection or the presence of complications. The amount of seroma aspirated in each session.

NCT ID: NCT04666051 Completed - Seroma Clinical Trials

Fibrin Glue in Inguinal Lymphadenectomy

Start date: May 2015
Phase: N/A
Study type: Interventional

Seroma is one of the most common encountered morbidities after inguinal lymph node dissection (ILND). It can cause not only much nuisance to both patients and doctors but also its presence can lead to many complications. This study aimed at evaluation of the role and effect of using fibrin glue on seroma reduction in patients undergoing ILND. Thirty-two patient have undergone ILND for various causes. The patients were randomized into two groups; 16 ILND in each. In one group, fibrin glue sealant was applied with a dose of 2ml per 100 cm2 surface area then drain placement was performed. Whereas, in the control group, only drain placement was used. Preoperative, operative and postoperative data were recorded and analyzed.

NCT ID: NCT04185480 Completed - Seroma Clinical Trials

Evaluating Hemopatch in Reducing Seroma Related Complications Following Axillary Lymph Node Dissection: a Pilot Study

HEIDI
Start date: June 16, 2020
Phase: N/A
Study type: Interventional

To evaluate if the use of Hemopatch in axillary lymph node dissection shows potential in reducing clinically significant seroma and seroma related complications, which might serve as a basis for a randomized controlled trial.

NCT ID: NCT03665883 Completed - Hernia, Inguinal Clinical Trials

Use of Diathermy Versus Blunt Dissection in TEP for Inguinal Hernia

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

There is a long debate whether monopoloar or blunt dissection should be adopted in TEP to minimise the chance of seroma formation. This study aims at study the effect on seroma formation (and pre-peritoneal drain output) by 2 techniques in randomised controlled trial.

NCT ID: NCT03650868 Completed - Breast Cancer Clinical Trials

The Effect of Thoracal Paravertebral Block on Seroma Reduction in Breast Surgery

Start date: September 1, 2018
Phase: N/A
Study type: Interventional

Thoracal paravertebral block (TPVB) is a commonly prefferred regional anesthesia technique to provide postoperative analgesia. In addition, the successful use of TPVB is reported for some seroma related pain cases. Postoperative analgesia in breast surgery is a difficult and overworked issue due to etensive surgery and complex innervation of the breast and in addition to this complex mechanisms, seroma accumulation has a negative effect for patients postoperatively. With this study, the investigators aimed to study the effect of TPVB on seroma reduction for breast cancer surgery.

NCT ID: NCT03647930 Completed - Seroma Clinical Trials

The Effect of Arista on Post-Operative Bleeding and Wound Drainage Following Mastectomy

Start date: May 15, 2012
Phase: N/A
Study type: Interventional

Study aim was to evaluate topical MPH on the risk of post-mastectomy seroma formation as measured by total drain output and total drain days.

NCT ID: NCT03590704 Completed - Seroma Clinical Trials

Safety of the Use of Compressive Taping in Seroma

Start date: June 6, 2017
Phase: N/A
Study type: Interventional

Seroma is the most common complication at the beginning of healing after surgery for breast cancer treatment. Its incidence varies in the literature from 2.5 to 90% and is defined as a collection of serous fluid that develops through skin flaps in the dead space after mastectomy or axillary dissection. The physiopathology for seroma formation has not yet been fully understood, but appears to be multifactorial with surgery being the main factor. Although seroma formation is not a threat to life, it can lead to important morbidity due to associated with necrosis, dehiscence, predisposition to sepsis, reduction of shoulder functions due to muscle weakness due to restriction of movement, prolonging the recovery period and, consequently, leading to delay in adjuvant therapy. The best seroma treatment is still not well defined in the literature and the compressive therapy aims to rebalance fluid exchange between the lymphatic system and blood, having as effects the increase of the interstitial pressure, the improvement of the effectiveness of muscular work, increased resistance of the skin and prevention new collection of interstitial fluid. Recently, the Kinesio® Taping method were inserted into clinical practice for its ability to reduce pain and local swelling. Objective: To evaluate the safety of taping in the seroma after surgical treatment of breast cancer. Methodology: This is a pre and post-clinical application of taping on the seroma in women submitted to surgical treatment for breast cancer in the Cancer Hospital III / INCA. The intervention was performed by applying the compression bandage over the seroma region for an average of five days, when the reassessment was performed.

NCT ID: NCT03512639 Completed - Seroma Clinical Trials

Arnica Montana and Bellis Perennis for Prevention of Seroma After Mastectomy

HOM
Start date: January 1, 2016
Phase: N/A
Study type: Interventional

Arnica montana and Bellis perennis for Prevention of Seroma Following Mastectomy.