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Prediction Study of Complications After Severe Trauma — PSCAT  

Sepsis Clinical Trial

Official title:
Identifying Severe Trauma Patients at High Risk of Post-traumatic Complications

Clinical Trial Summary

The purpose of this study is to evaluate a clinically and economically most effective diagnostic algorithm for prediction of post-traumatic complications in a multicenter sample of severe trauma patients.

Clinical Trial Description

Trauma is a major public health problem worldwide, ranking as the fourth leading cause of death. One of the most serious complications of major trauma is sepsis, which often induces sequential multiple organ dysfunction syndrome (MODS). There were still no specific biomarkers to predict the susceptibility of complications and outcomes, which leading to the limited prevention methods and the high mortality rate of severe trauma patients. Previous studies from our and other group have found some sepsis and MODS predictors, including genetic polymorphisms, serum cytokines and cell-surface markers. The purposes of this multi-center observational study is to select biomarkers and evaluate a clinically and economically most effective diagnostic algorithm for prediction of complications in severe trauma patients. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01713205
Study type Observational
Source Daping Hospital and the Research Institute of Surgery of the Third Military Medical University
Contact Anqiang Zhang, MD
Phone +86-23-68757402
Email zhanganqiang@126.com
Status Recruiting
Phase
Start date October 2012
Completion date December 2023
View Details
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