View clinical trials related to Sedative Toxicity.
Filter by:There is a drug-related death crisis in Scotland. The majority of these deaths have involved the misuse of opiates (e.g. heroin) and benzodiazepines (e.g. valium) which cause an individual to stop breathing. The Advanced Respiratory Monitoring Events in Drug Toxicity (ARM-ED) study is a study investigating whether a wearable sensor can help detect problems with breathing in patients who have had drugs or medications that may cause this effect. The study will span a year and will study two groups of patients - those who attend with actual or expected respiratory depression secondary to acute drug toxicity and individuals who have undergone procedural sedation and analgaesia in the Emergency Department.
There is limited data regarding sound levels and burden in the pediatric cardiac critical care unit and how this compares with WHO standards. We seek to record this data and correlate sound level with bolus sedation administration, patient delirium scores, and patient heart rate trends. Primary Outcomes - 1 peak sound level in cardiac ICU in decibels - 2 Mean sound level in cardiac ICU in decibels - 3 Compare sound levels to WHO recommendations Secondary Outcomes - 1 To explore patient and unit factors that might influence these levels - 2 To analyze sound levels in post-operative neonates, versus infants, versus children - 3 To analyze patients on invasive versus non-invasine versus no ventilation