Impact of Cigar Flavor on Tobacco Use Behaviors and Addiction in Dual Users
The purpose of this study is to understand addiction to filtered cigars (FCs) compared to cigarettes in young adults, ages 21-34, who smoke both cigarettes and cigars. We are also looking to see if flavors, such as fruit or menthol, make FCs more addictive and if there are differences between men and women. Participants will receive 2 weeks supply of FCs, one week flavored and another week unflavored. You will be randomized (like flipping a coin) to which type of FC you will receive first. The study will: - take about 3-4 hours of your time per week over 3-5 weeks. - be conducted remotely by phone, video call, email, and mail. - require a smart phone to answer 5 quick surveys a day - you will need to answer 4 weekly surveys - take part in a weekly video or phone call with research staff - supply three saliva samples to be later tested for nicotine and other toxicants - and use a device to measure your carbon monoxide levels four times a day. You will be compensated for your time.
NCT04487470 — Tobacco Use Disorder
Status: Recruiting
http://inclinicaltrials.com/tobacco-use-disorder/NCT04487470/
MedPAC Hotline: A Medical Peer Addiction Counselling Hotline Service for Drug-abusing Youth and Young Adults
Aim: Providing peer counselling service delivered by student counsellors with a medical background via a hotline to drug-abusing youth and young adult aged 35 or below. Objectives: i. To raise anti-drug awareness of young people in general and identify high-risk/hidden drug-abusing youth and young adult aged 35 or below in Hong Kong; and ii. To train university students with a medical background as peer counsellors; and iii. To provide drug abuse hotline service by students with a medical background as peer counsellors to drug-abusing youth and young adult aged 35 or below, and other people who call for help, including drug abusers' family members, friends, and professionals; and iv. To improve the drug-abusing youth and young adult' knowledge about the hazard of drug abuse, negative attitude, and perception towards the drug abuse through the telephone peer counselling service provided by students with medical background; and v. To increase the intention to quit and the help-seeking behavior among the drug-abusing youth and young adult; vi. To increase reduction rate and abstinence rate from drug abuse, and decrease the relapse rate among drug-abusing youth and young adult through the telephone peer counseling service.
NCT04461314 — Drug Abuse
Status: Recruiting
http://inclinicaltrials.com/drug-abuse/NCT04461314/
Journaling and Addiction Recovery: Piloting "Positive Recovery Journaling"
The main objective of this study is to pilot test the Positive Peer Journaling (PPJ) [later renamed "Positive Recovery Journaling" (PRJ)] intervention and its feasibility and acceptability. A second objective is to compare individuals assigned to PPJ to individuals in a treatment as usual control group.
NCT04458181 — Addiction
Status: Completed
http://inclinicaltrials.com/addiction/NCT04458181/
Temporal Interference Neurostimulation and Addiction
This project aims to develop a line of research using new non-invasive neurostimulation technology to treat adults with opioid use disorders (OUDs). In the short term, the investigators aim to identify novel target brain regions for neurostimulation treatment and characterize their effects behaviorally and neurally. In the longer term, investigators aim to use these preliminary data to justify NIH sponsored clinical trials to apply transcranial direct current stimulation and non-invasive deep brain stimulation to these areas to partially or completely disrupt addiction.
NCT04432064 — Substance Use Disorders
Status: Recruiting
http://inclinicaltrials.com/substance-use-disorders/NCT04432064/
Online Cognitive Behavior Therapy in Routine Addiction Care for Comorbid Sleep Problems in Alcohol Use Disorder
The main goal is to study the effects of internet-delivered cognitive behavioural therapy with minimum guidance for comorbid sleep problems in alcohol use disorder, in routine addiction care.
NCT04402619 — Insomnia
Status: Recruiting
http://inclinicaltrials.com/insomnia/NCT04402619/
Technologically-Augmented Referrals to Mitigate Addiction Consequences (TARMAC)
The implementation of screening and intervention for substance use disorders, such as Screening Brief Intervention Referral to Treatment (SBIRT), in the primary care setting has faced several challenges. In the past, physicians have cited barriers such as lack of time, lack of access to treatment, and lack of financial resources. To overcome some of the barriers to screening and prevention of substance use disorders, many researchers have begun to explore novel approaches using web-based and mobile technology. While the quality of evidence is often inconsistent, there is promising research to show that interventions utilizing web-based or mobile technology for alcohol and other substance abuse can be effective. Features such as tailored feedback have shown to be more effective than similar programs without feedback, and interventions that combine self-administered therapy in conjunction with therapist-direction interventions show greater reductions in addictive behavior. In this project, the investigators proposed to enhance the Screening Brief Intervention Referral to Treatment (SBIRT) with a digital tool that aims to save physician time and improve patient adherence to treatment goals, through extensive use of shared decision making, patient self-monitoring and goal tracking, and real-time tailored patient feedback and text follow-up for patients. Increase the screening and referral of those patients at risk for substance use disorder (SUD) thereby increasing the number of patients receiving higher level substance use treatment. A total of 500 patients will be screened and randomized into two groups. 250 in the Technology Augmented Treatment group (intervention group) and 250 in the control group. The Washington State University research team, lead by Dr. McPherson, will screen and recruit subjects at CHAS Valley Clinic in Spokane, WA. Subjects in both groups will be followed up for 30 days. At the initial study enrollment visit, the intervention group will be asked questions on an iPad about their eligibility. After the initial visit, subjects in the intervention group will receive up to 4 texts/day on his/her phone that will ask questions about their health after the visit. The control group will be asked questions on an iPad and will be given a call 30 days after to ask questions about their health.
NCT04401215 — Substance Use Disorders
Status: Completed
http://inclinicaltrials.com/substance-use-disorders/NCT04401215/
Optimization of Non-Invasive Brain Stimulation for Treatment of Addiction
The purpose of this study is to assess the effects of transcranial Direct Current Stimulation (tDCS) applied in conjunction with Transcranial Ultrasound (TUS) for the treatment of addiction in opiate use disorder with chronic pain. The investigators hypothesize that there will be a decrease in drug use and improved psychosocial assessments with active stimulation, when compared to sham stimulation.
NCT04379115 — Chronic Pain
Status: Recruiting
http://inclinicaltrials.com/chronic-pain/NCT04379115/
Modification of Cue Reactivity by Neurofeedback in Human Addiction
The project is geared towards the understanding of how to increase cognitive control over cue reactivity and drug craving.
NCT04366505 — Alcohol Use Disorder (AUD)
Status: Not yet recruiting
http://inclinicaltrials.com/alcohol-use-disorder-aud/NCT04366505/
Participatory System Dynamics vs Audit and Feedback: A Cluster Randomized Trial of Mechanisms of Implementation Change to Expand Reach of Evidence-based Addiction and Mental Health Care
The most common reasons Veterans seek VA addiction and mental health care is for help with opioid and alcohol misuse, depression and PTSD. Research evidence has established highly effective treatments that prevent relapse, overdose and suicide, but even with policy mandates, performance metrics, and electronic health records to fix the problem, these treatments may only reach 3-28% of patients. This study tests participatory business engineering methods (Participatory System Dynamics) that engage patients, providers and policy makers against the status quo approaches, such as data review, and will determine if participatory system dynamics works, why it works, and whether it can be applied in many health care settings to guarantee patient access to the highest quality care and better meet the addiction and mental health needs of Veterans and the U.S. population.
NCT04356274 — Depression
Status: Enrolling by invitation
http://inclinicaltrials.com/depression/NCT04356274/
Behavioral Weight Loss Treatment for Individuals With Food Addiction
The purpose of this research study is to examine how well an existing weight loss treatment works for individuals with food addiction. Treatment will consist of a preliminary 12-week RCT pilot of the feasibility and effectiveness of behavioral weight loss (BWL) compared to a waitlist control.
NCT04311450 — Overweight and Obesity
Status: Completed
http://inclinicaltrials.com/overweight-and-obesity/NCT04311450/