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Mindfulness Meditation for Epilepsy - MIME

Mindfulness Meditation for Epilepsy: Effect of Mindfulness Meditation Practice on Quality of Life and EEG Activity in Refractory Epilepsy

In one-third of epileptic patients treated in France, seizures persist despite drug treatment. These so-called "refractory" epilepsies are among the most severe. Only a minority of patients with refractory epilepsy can undergo surgery. The other options available are based on brain or vagus nerve stimulation interventions which clinical effectiveness is still being studied. Alternative therapies are needed both to decrease the frequency of patients' seizures and to improve their quality of life. The practice of mindfulness meditation has recently been included in the recommendations of the International League Against Epilepsy in order to alleviate anxiety or depression comorbid symptoms. This study falls within this framework by targeting two aspects of the pathology.

NCT04687904 — Epilepsy
Status: Recruiting
http://inclinicaltrials.com/epilepsy/NCT04687904/

Mindful Meditation for Epidural Catheter Placement

Effects of a Brief Mindful Meditation Intervention on Patient Anxiety and Satisfaction for Labor Epidural Catheter Placement: a Randomized Controlled Trial

Given the high prevalence of neuraxial analgesia use during labor and the anxiety associated with these procedures, a method to decrease this anxiety could benefit millions of laboring women each year. Mindfulness practice has been used by many groups to decrease anxiety during pregnancy with optimistic results. However, there has been no major study evaluating the role of mindfulness interventions on anxiety associated with neuraxial placement. The purpose of our study is to address this gap in knowledge.

NCT04687085 — Pain
Status: Completed
http://inclinicaltrials.com/pain/NCT04687085/

Compassion Meditation vs. Health Education for Veterans

Efficacy of Mind-Body Approaches for the Treatment of Chronic Pain With Psychological Comorbidity

Chronic pain (CP) is a major health problem for military Veterans, and CP is often associated with comorbid mental health problems, including posttraumatic stress disorder (PTSD) and depression. CP with psychological comorbidity is associated with increased healthcare costs, medication use, risk of suicide and rates of disability and reduced quality of life. Current empirically supported treatments do not always lead to substantial improvements (up to 50% of patients drop out or are do not respond to treatment). This project was designed to evaluate the efficacy of a novel intervention for addressing these challenges. Compassion meditation (CM), a meditative practice that focuses on the wish to remove suffering, is a contemplative practice that has promise for the amelioration of physical and mental health problems as well as promoting positive affect and improving quality of life. This study will evaluate the efficacy of Cognitively-Based Compassion Training for Chronic Pain with Psychological Comorbidity (CBCT-CP+) compared to Health Education while Living with Pain (H.E.L.P.) control condition, in a sample of among Veterans with CP conditions and psychological comorbidity.

NCT04651296 — Depression
Status: Recruiting
http://inclinicaltrials.com/depression/NCT04651296/

Online Trial of Meditation and Behavior

Identifying Neural Correlates of Altruism

This study investigates how different types of meditation may affect behaviors and emotions. The study is conducted entirely online and involves listening to 4-weeks of a guided meditation training. The meditation involves either Loving-Kindness or Relaxation techniques. The purpose of the study is to assess changes in behaviors and emotions using standard questionnaires, reports of real-world behavior, and online behavioral tasks. The overarching goal is to help clarify how mind-body practices may improve some aspects of well-being.

NCT04632875 — Meditation
Status: Completed
http://inclinicaltrials.com/meditation/NCT04632875/

Meditation Accelerated Brain Stimulation for Depression - MediTMS

Meditation Accelerated Brain Stimulation for Depression

Repetitive Transcranial magnetic stimulation (rTMS) is an FDA-approved treatment for depression that involves brief magnetic stimulation pulses on the dorsolateral prefrontal cortex (DLPFC) brain region. The ultimate goal of this treatment is to increase excitability and long-term plasticity in DLPFC, a brain region shown to be hypo-active in depression. Unfortunately, rTMS only has low to moderate efficacy; remission rates for patients range from ~15-30% in large randomized controlled trials. The focus of this research is to develop a next-generation rTMS protocol that is guided by the basic principles underlying brain plasticity, in order to improve the efficacy of rTMS for the treatment of depression. Specifically, in this study the investigators will test rTMS paired with a depression-relevant cognitive state of internal attention.

NCT04586699 — Depression
Status: Recruiting
http://inclinicaltrials.com/depression/NCT04586699/

Improving the Mental Health of Resident Physicians and Fellows Through Transcendental Meditation

Improving the Mental Health of Resident Physicians and Fellows : Reducing Burnout & Enhancing Resilience Through Transcendental Meditation

This proposal aims to optimize resident physician and fellow wellness and performance at Banner University Medical Center through an evidence-based stress reduction program, Transcendental Meditation (TM). It is particularly timely due to the enormous pressure and stress that residents face as front-line workers during the current 2019 novel coronavirus (COVID-19) pandemic. Participants will be randomly assigned to the TM training (group 1), or delayed TM training (group 2). Study outcomes will be assessed at baseline and at 1 and 3 months post-training. Participants who are assigned to group 2 , will receive the TM training following the three month assessment, and then complete assessments at 1 and 3 months post-training. These assessment tools look at anxiety (Generalized Anxiety Disorder Scale-GAD-7), depression (Patient Health Questionnaire (PHQ-9), insomnia (Pittsburgh Sleep Quality Index PSQI), psychological distress (Brief Symptom Inventory BSI18), burnout (Maslach Burnout Inventory-MBI), resilience (Conner-Davidson Resilience Scale- RISC), and alcohol use (Alcohol Use Disorder Identification Test - AUDIT).

NCT04586309 — Depression
Status: Withdrawn
http://inclinicaltrials.com/depression/NCT04586309/

Virtual Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers

Virtual Health Education vs Meditation in Irreversible Age-Related Vision Loss Patients and Their Caregivers: A Pilot Randomized Controlled Trial

Vision loss is common among older adults and leads to an increased risk for depression and difficulties in daily tasks, thus requiring dependence on caregivers. This study will assess the feasibility of providing two virtual interventions, Sahaj Samadhi Meditation (SSM) and Health Enhancement Program (HEP), to supplement care of patients with irreversible age-related vision loss (IARVL) and their caregivers, with the goal of enhancing mental health and quality of life.

NCT04583748 — Depression
Status: Withdrawn
http://inclinicaltrials.com/depression/NCT04583748/

A MEDITATION PROGRAM IN HIGH-BURDEN INFORMAL CAREGIVERS

EFFECTS OF A MEDITATION PROGRAM ON THE QUALITY OF LIFE IN HIGH-BURDEN INFORMAL CAREGIVERS

The aim of the present study was to investigate in high burden caregivers the effects of a face-to-face meditation program during four weeks (16 hours) on physiological parameters, psychological state and vagal nerve activity comparing with a control group.

NCT04570826 — Caregivers Burnout
Status: Completed
http://inclinicaltrials.com/caregivers-burnout/NCT04570826/

My Mindful Moments: A Mindfulness Meditation and Digital Art Activity

My Mindful Moments: A Mindfulness Meditation and Digital Art Activity

The purpose of this evidence-based practice project is to evaluate the feasibility of providing a relaxation mindfulness meditation and an expressive digital arts activity among clinical staff at Dana Farber Cancer Institute .

NCT04557033 — Mindfulness
Status: Completed
http://inclinicaltrials.com/mindfulness/NCT04557033/

Breathing Techniques and Meditation for Health Care Workers During COVID-19 Pandemic

Breathing Techniques and Meditation for Health Care Workers During COVID-19

This phase I trial investigates breathing techniques and meditation for health care workers during COVID-19 pandemic. Breathing techniques and medication may help manage stress and improve lung health. The goal of this trial is to learn if breathing techniques and meditation may help to reduce stress and improve lung health in health care workers during the COVID-19 pandemic.

NCT04482647 — COVID-19 Infection
Status: Active, not recruiting
http://inclinicaltrials.com/covid-19-infection/NCT04482647/