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Scoliosis clinical trials

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NCT ID: NCT05454800 Recruiting - Scoliosis Clinical Trials

Effects of Physical Activity Counseling in Patients With Adolescent Idiopathic Scoliosis

Start date: July 7, 2022
Phase: N/A
Study type: Interventional

Scoliosis is a three-dimensional deformity of the spine of unknown etiology and is clinically defined as 10° or more lateral curvature of the spine. Although there are different types of scoliosis, the most common type is adolescent idiopathic scoliosis (AIS), which starts at the age of 10. AIS can affect body alignment, spine and soft tissues and cause physical problems such as postural disorder, cosmetic trunk deformity, decreased flexibility of the spinal column, changes in spinal muscle characteristics, and back pain. The aim of our study is to examine the effects of physical activity counseling on physical activity level and posture, perception of deformity and quality of life in patients with AIS.

NCT ID: NCT05452252 Completed - Clinical trials for Scoliosis Idiopathic

Mandibular Evaluation and Facial Analysis In Adolescents With Idiopathic Scoliosis

Start date: March 1, 2022
Phase:
Study type: Observational [Patient Registry]

Fifty-eight participants with AIS and 45 healthy controls were included in the study. Active mandibular movements including depression, protrusion, and left-right deviation were assessed with a ruler. Facial anthropometry was measured on facial shape on photograph, and phenotype and asymmetry were determined from the acquired anthropometric facial data. Neck mobility was evaluated in movements of flexion, extension, right-left lateral flexion, and right-left rotation using a standard flexible tape. The Fremantle Neck Awareness Questionnaire was used to assess neck awareness. Neck pain in the previous week was measured with a Visual Analog Scale.

NCT ID: NCT05433545 Recruiting - Spinal Deformity Clinical Trials

Adherence to Physiotherapy Scoliosis Specific Exercises in Adolescents With Spine Deformity: Development of a New Questionnaire

Start date: March 22, 2022
Phase:
Study type: Observational

This study aims to develop a new instrument capable of providing an efficient measure of the quality and quantity of adherence to Physiotherapy Scoliosis Specific Exercises performed at home by growing patients with spinal deformity undergoing conservative treatment at a specialized institution. The development of a questionnaire in a Rasch environment and specifically developed for this population will ensure greater sensitivity and specificity of the questionnaire.

NCT ID: NCT05424419 Completed - Scoliosis Clinical Trials

Add-on Nighttime Bracing in Adolescent Idiopathic Scoliosis

Start date: January 2, 1997
Phase:
Study type: Observational

Bracing is an accepted standard therapy for idiopathic scoliosis at Cobb angle ranges between 25° and 45°. However, it is unclear, if a specifically tailored regimen of daytime and nighttime braces (=double brace) yields superior results compared to the standard treatment (single brace for day and night). These two treatment regimens were investigated in the study.

NCT ID: NCT05423509 Completed - Clinical trials for Scoliosis Idiopathic Adolescent Treatment

Myofascial and Articular Treatment of Adolescent Idiopathic Scoliosis

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

Randomized controlled trial of participants with scoliosis into standard treatment with observation/bracing and the other group will have the added treatment of dynamic myofascial manipulation for 6 months.

NCT ID: NCT05404620 Not yet recruiting - Clinical trials for Idiopathic Scoliosis

Effects of Schroth Method and Proprioceptive Neuromuscular Facilitation Technique in Patients With Idiopathic Scoliosis

Start date: June 2022
Phase: N/A
Study type: Interventional

The aim of this study is to compare the effects of schroth method and proprioceptive neuromuscular facilitation techniques on pain, mobility, and quality of life in patients with idiopathic scoliosis.

NCT ID: NCT05392504 Completed - Clinical trials for Scoliosis Idiopathic

Effects of Core Stabilization Exercises vs. Schroth's Program on Posture and Quality of Life in Females With Scoliosis.

Start date: June 1, 2022
Phase: N/A
Study type: Interventional

The objective of this study is to compare the effects of core stabilization exercises versus schroth's program on posture and quality of life in females with idiopathic scoliosis

NCT ID: NCT05391412 Recruiting - Bleeding Clinical Trials

Effect of Prophylactic Fibrinogen Concentrate In Scoliosis Surgery

EFISS
Start date: June 6, 2022
Phase: Phase 4
Study type: Interventional

EFISS is a prospective, randomized, placebo-controlled trial testing the feasibility, safety and efficacy of prophylactic administration of fibrinogen in paediatric spinal surgery. The study is monocentric and will be conducted in University Hospital Brno, Czech Republic. This is a pilot study in which the primary objective will be to evaluate the feasibility of a clinical trial in 32 selected patients undergoing scoliosis surgery. Participants will be randomized into study groups in a 1:1 allocation ratio and followed up for 28 days after surgery. The expected duration of this clinical trial is 8 months.

NCT ID: NCT05381896 Completed - Clinical trials for Adolescent Scoliosis

The Effect of Inspiratory Muscle Training on Postural Stability, Posture Perception and Trunk Rotation in Children With Adolescent Idiopathic Scoliosis.

Start date: May 23, 2022
Phase: N/A
Study type: Interventional

Trunk rotation and distortion of the rib cage, which are common in patients with adolescent idiopathic scoliosis, result in abnormal configuration of the diaphragm and intercostal muscles. This reduces the capacity of the respiratory muscles to produce force, and results in respiratory muscle weakness. The diaphragm, which is the major respiratory muscle, is also a component of the core muscles responsible for postural stability. Therefore, diaphragm muscle weakness results in deterioration of postural stability. Our aim in this study is to investigate the effect of inspiratory muscle training added to the routine scoliosis exercise program on postural stability and posture perception.

NCT ID: NCT05379868 Not yet recruiting - Clinical trials for Adolescent Idiopathic Scoliosis

Posterior Column Spinal Osteotomies in the Treatment of Adolescent Idiopathic Scoliosis

ASPO
Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Background: Posterior column osteotomies (PCO) are routinely used to facilitate curve correction in surgical treatment of adolescent idiopathic scoliosis (AIS). Data regarding routine use of PCO is controversial, with conflicting data for coronal and sagittal plane correction and clinical benefit. Use of PCO has not been studied in the surgical treatment of AIS in a prospective randomized clinical trial. Study Design: A randomized, multicenter clinical trial on children and adolescents undergoing posterior spinal fusion for idiopathic scoliosis using pedicle screw instrumentation. Sixty consecutive adolescents will be randomized into PCO or no PCO group after surgical exposure of the spine in 1:1 ratio. Aims and Hypothesis: To compare PCO vs. no PCO groups for the correction of coronal and sagittal plane curve in children undergoing posterior spinal fusion for AIS. The investigators hypothesize that the correction of coronal curve and hypokyphosis will be better in PCO group without increasing blood loss or complications. Inclusion criteria: Adolescents (aged 10 to 21 years of age) undergoing corrective surgery for idiopathic scoliosis using pedicle screw technique. Exclusion criteria: Coagulation disorder, smoking, unwilling to consent, vertebral column resection, need for anteroposterior surgery. Main outcome parameters: Primary outcome is the radiographic correction (Coronal and sagittal plane). Secondary outcomes include health-related quality of life (Scoliosis Research Society 24 outcome questionnaire), postoperative pain, rib hump, operative time, blood loss, hospital stay, and complications. Ethical aspects: Ethical committee approval will be obtained. An informed consent will be obtained from all children and their parents. Time schedule and budget: This study has ethical committee approval.There will be no extra costs as all information gathered will be part of normal surgical treatment of AIS. A part-time research nurse has been hired to take care of data collection into the database.