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Scoliosis clinical trials

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NCT ID: NCT03719807 Completed - Clinical trials for Scoliosis Idiopathic

Protocol of Accelerated Rehabilitation Following Surgical Correction of Adolescent Idiopathic Scoliosis

PARIS
Start date: December 1, 2018
Phase: N/A
Study type: Interventional

This study aims to identify whether an accelerated physiotherapy led rehabilitation programme for adolescents undergoing idiopathic scoliosis correction surgery can be delivered safely and effectively post-operatively, and whether it might improve activity levels and quality of life outcomes for the study group. This research is being conducted as previous research indicates that up to 41% of patients who have surgical correction of their scoliosis either return to athletic activity at a lower level than before, or they do not return to athletic activity at all. This is despite significant advancement in the instrumentation being used in recent years which makes the corrections more stable and robust. Some studies have shown that surgically treated AIS patients have significantly reduced physical function and quality of life scores, and that this could be improved with exercise. So far no trials have investigated whether post-operative rehabilitation can improve quality of life for these patients. The initial study will be a pilot study, comprising of 20 participants in a small, pragmatic randomised controlled trial (RCT). It will be conducted at The Royal Orthopaedic Hospital, a specialist National Health Service (NHS) orthopaedic centre. Adolescents (between 11-18 years of age) who have a diagnosis of adolescent idiopathic scoliosis (AIS) and are on the waiting list for surgical correction of this scoliosis will be included. The study will compare a post-operative accelerated rehabilitation programme (commenced at 6 weeks post surgery) with usual care and investigate if the accelerated intervention can be delivered safely and effectively after this procedure. Following surgery, both groups will have the same inpatient rehabilitation up until the point of discharge home. The intervention group will then complete 12 sessions of physiotherapy as an outpatient, which starts at 6 week post-op. The usual care group will not have any further physiotherapy, in line with current standard practice at this centre. Both groups will be assessed using patient reported outcome measures pre-operatively, and at 6 months and 12 months post-operatively, to assess function and quality of life.

NCT ID: NCT03686371 Completed - Clinical trials for Idiopathic Scoliosis

Evaluation of Pain Following Scoliosis Surgery.

RACHIDOL
Start date: January 2, 2018
Phase:
Study type: Observational

The main objective of this study was to evaluate acute pain following scoliosis surgery in adolescent.

NCT ID: NCT03675984 Completed - Clinical trials for Idiopathic Scoliosis

Development of Exercise Protocol for Scoliosis Using Surface Electromyography(S-EMG)

Start date: December 22, 2016
Phase: N/A
Study type: Interventional

There has been much effort in recent years to better understand the causes of idiopathic scoliosis (IS). Some studies suggested muscle imbalance as a cause of scoliosis based on asymmetric muscular activation. Surface electromyography can evaluate asymmetrical muscular weakness. Therefore, the peak amplitude values can be used to compare the side to side differences in paraspinal muscles. From these findings the investigators improve the exercise method of IS according to muscle weakness and curve pattern.

NCT ID: NCT03617120 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

Ergonomic Brace Wear for Adolescent Idiopathic Scoliosis

Start date: August 1, 2018
Phase: N/A
Study type: Interventional

This study assesses the effectiveness of a new scoliosis brace design for adolescent idiopathic scoliosis (AIS) patients, named Ergonomic Brace, by comparing the outcome with hard brace in terms of three aspects: 1. To assess the efficacy in spinal correction 2. To evaluate the improvement made to the body appearance of AIS subjects 3. To evaluate the impacts on the quality of life (QoL) of AIS subjects All participants will be fitted with an Ergonomic Brace and required to wear it during the days of experiment only. The ongoing treatment with hard brace will not be substituted with the Ergonomic Brace, unless its immediate treatment effect is equivalent to hard brace and with approval from the doctor.

NCT ID: NCT03539770 Completed - Clinical trials for Scoliosis Idiopathic Adolescent

Lung Regeneration After Posterior Spinal Fusion for Adolescent Idiopathic Scoliosis

Start date: November 1, 2014
Phase:
Study type: Observational

Adolescent Idiopathic Scoliosis (AIS) is a curvature of the spine that occurs in 1-2% of otherwise healthy children, and requires corrective surgery, posterior spinal fusion (PSF) in ~10% of cases. Some studies suggest that pulmonary function is reduced in AIS and that PSF improves pulmonary function. The lung is composed of a large number of branching airways that terminate in gas exchanging units called alveoli, and the number and structure of these alveoli are partially dependent upon lung volume and the forces to which they are exposed--two factors predicted to be altered in AIS. This study uses MRI imaging of inhaled helium to quantify alveolar structure in children with and without AIS before and one-year after PSF. The goals of the study are to determine if alveolar architecture or number are altered in AIS and whether PSF impacts these same measures.

NCT ID: NCT03514082 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

Oxygen Consumption in Adolescent Idiopathic Scoliosis

Start date: April 15, 2018
Phase:
Study type: Observational

Adolescent Idiopathic Scoliosis (AIS) is a rotational deformity of the spine that could be seen 2-3% of population. Conservative treatment of AIS with 20-45 degree lateral flexion angle (Cobb) includes brace and therapeutic exercises. Some gait abnormalities were defined like decreased torsional movements of spine, increased muscular work and energy expenditure in AIS. Additionally wearing a brace limits pelvic motions and affects pendulum-like mechanism of gait. Our aim was to investigate gait energy consumption, pulmonary functions, balance and lower extremity loading symmetry in AIS subjects who are getting conservative treatment.

NCT ID: NCT03513120 Completed - Clinical trials for Adolescent Idiopathic Scoliosis

Return to Sport After Posterior Spinal Fusion

Start date: March 8, 2018
Phase:
Study type: Observational

The primary purpose of this prospective study is to determine when adolescent athletes with idiopathic scoliosis are able to return to sports participation after posterior spinal fusion surgery.

NCT ID: NCT03483844 Completed - Scoliosis Clinical Trials

Low-dose Dual-energy CT for the Pre-surgical Planning of Patients With Progression of Scoliosis

Start date: January 16, 2018
Phase:
Study type: Observational

The aim of the study is to evaluate the diagnostic accuracy of low-dose dual energy CT in the pre-surgical planning of patients with progression of scoliosis

NCT ID: NCT03464318 Completed - Clinical trials for Idiopathic Scoliosis

Low-dose Digital Radiographs in the Idiopathic Scoliosis

Start date: January 27, 2018
Phase:
Study type: Observational

The aim of the study is to evaluate the intraobserver repeatability and the interobserver reproducibility of low-dose radiographs with a HELIOS DRF (CAT) imaging system in patients with idiopathic scoliosis.

NCT ID: NCT03459105 Completed - Scoliosis Clinical Trials

Ultrasound-assisted Versus Conventional Landmark-guided Spinal Anesthesia in Patients With Abnormal Spinal Anatomy

Start date: March 13, 2018
Phase: N/A
Study type: Interventional

Spinal anesthesia can be challenging in patients with lumbar scoliosis or previous lumbar spine surgery. This study aims to evaluate whether the use of the ultrasound-assisted spinal anesthesia reduces the number of passes required to successful dural puncture compared with the conventional surface landmark-guided technique in patients with abnormal spinal anatomy.