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Sars-CoV2 clinical trials

View clinical trials related to Sars-CoV2.

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NCT ID: NCT04397172 Terminated - COVID Clinical Trials

Intensive Care Associated Complications and Outcome of Acute Respiratory Distress Syndrome Due to COVID-19

Start date: April 9, 2020
Phase:
Study type: Observational

COVID-19 patients with a severely symptomatic progression with development of an Acute respiratory distress syndrome (ARDS) due to SARS-CoV-2 need prolonged intensive care treatment involving pharmacological immobilization, sedation and mechanical ventilation, leaving them at a very high risk for developing Critical illness myopathy (CIM). CIM is associated with increased mortality and significant consequences for recovery and the ability to return to normal daily life. Up to date, there are no studies investigating the mid- or long-term course of the novel COVID-19 disease. The present study therefore aims to evaluate the clinical outcome of patients with ARDS due to SARS-CoV-2 with special attention to the development of CIM and its underlying causes. To provide the possibility of early diagnosis of CIM, critically ill patients will be regularly screened for muscle membrane alterations using (Muscle velocity recovery cycles) MRVC measurements. The primary endpoint is the incidence of CIM in patients with ARDS due to SARS-CoV-2, diagnosed according to the current diagnostic criteria.

NCT ID: NCT04395794 Recruiting - Sars-CoV2 Clinical Trials

SARS-CoV-2 Disguise Study

Disguise
Start date: May 7, 2020
Phase:
Study type: Observational [Patient Registry]

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a pandemic disease with worldwide spreading. Limited data are existed regarding SARS-CoV-2 positive carriers among asymptomatic medical employees in non-profile infectious clinic, e.g. cardiovascular clinic, routinely working in the pandemic region with two million inhabitants. The aim is to test the percentage and increase of the SARS-CoV-2 positive carriers among asymptomatic medical employees in high-volume cardiovascular center in routine clinical practice.

NCT ID: NCT04395716 Withdrawn - Covid-19 Clinical Trials

A Study of ResCureā„¢ to Treat COVID-19 Infection

Start date: January 2020
Phase: Phase 1
Study type: Interventional

This is a Phase I open-label interventional study which will test the efficacy of ResCureā„¢ in the treatment of patients with COVID-19 infection.

NCT ID: NCT04395599 Recruiting - Surgery Clinical Trials

Risk of Air Contamination During Visceral Surgery in COVID19 Patients

COELIOCOVID
Start date: November 16, 2021
Phase: N/A
Study type: Interventional

Sars-Cov2 has been found in the digestive tract, as well as the respiratory tract. Protection of health care workers during surgery has been increased and some guidelines advocate for abandoning laparoscopy in COVID19 patients for fear of contamination, evenghtough this does not benefit the patient. However, Sars-Cov2 contamination risk during visceral surgery remains unknown. Inadequate protection is unnecessary costful and can be inefficient if too binding. Our hypotheses are that 1) Sars-Cov 2 can travel through droplet and air during visceral surgery. 2) Laparoscopy, because of the pneumoperitoneum and its leaks, warrant more air contamination whereas laparotomy warrant more droplet contamination, which would justified increased protection.

NCT ID: NCT04394429 Recruiting - Sars-CoV2 Clinical Trials

Endotracheal Tube Obstruction in Covid-19 Patients Requiring Mechanical Ventilation

TubeObs-Covid
Start date: April 24, 2020
Phase:
Study type: Observational

The COVID-19 pandemic is very present in our region, the Grand-Est region is considered as one of the first COVID-19 epicentres in France. COVID-19 causes an acute respiratory distress syndrome requiring prolonged mechanical ventilation in resuscitation.

NCT ID: NCT04393974 Recruiting - Cancer Clinical Trials

COVID-19 and Cancer Patients

OnCovid
Start date: March 24, 2020
Phase:
Study type: Observational

Routinely collected data will be used to assess the morbidity and mortality of cancer patients following a positive COVID-19 infection.

NCT ID: NCT04392323 Completed - Sars-CoV2 Clinical Trials

Incidence of COVID-19 Test Conversion in Post-surgical Patients

Start date: May 13, 2020
Phase: N/A
Study type: Interventional

The current Sars-CoV-2 (COVID-19) pandemic has created major changes in how physicians perform routine healthcare for our patients, including elective and non-elective surgical procedures. Beginning on March 16th, 2020 Northwell Health postponed all elective surgeries. As the incidence of COVID-19 cases begins to decrease and hospital volume improves we need to ensure the safety of our patients planning surgical procedures. However, at this time there is a scarcity of data regarding the COVID-19 test conversion rate in surgical patients. Our goal is to determine the COVID-19 test conversion rate in these patients to better guide strategies for restarting surgical care in a large-scale pandemic. Patients will be routinely tested with serology and PCR for COVID-19 24-48 hours prior to their scheduled surgery. Those who provide informed consent will be re-tested 12-16 days after discharge from the hospital to determine any potential nosocomial infection rate. Patients will also answer a few questions during their retest to allow the study team to gauge exposure risk postoperatively after leaving the hospital.

NCT ID: NCT04391829 Recruiting - COVID-19 Clinical Trials

Detection of SARS-CoV-2 in Semen of COVID-19 Positive Males

COVIDSPERM
Start date: August 31, 2020
Phase: N/A
Study type: Interventional

The objectives of the study, are to describe detection of SARS-CoV-2 in the semen of COVID-19 positive patients, the duration of positive semen and to investigate the impact on semen quality, thereby providing insights into the early impact on male reproductive function.

NCT ID: NCT04387838 Completed - Sars-CoV2 Clinical Trials

Study of the SARS-COV-2 (COVID-19) Serological Profile of an Army Training Hospital Staff

SEROSARSCOV
Start date: May 14, 2020
Phase:
Study type: Observational

Emerging in China in December 2019, Covid-19, whose pathogen is SARS-Cov-2, was declared a global pandemic in March 2020. The clinical presentation is highly variable, ranging from asymptomatic forms to acute respiratory distress and even death. Transmission occurs through droplets, with a R0 of approximately 3. Rapidly, population protection measures were put in place by governments, including the confinement of all persons whose functions were not considered essential and the closure of educational institutions. Health care institutions are places at risk of Covid-19 transmission and hospital staff are particularly exposed, either through direct contact with patients, contact with exposed persons or through the environment. In order to protect personnel, hygiene measures were immediately recalled and reinforced. This study is aimed at evaluating the incidence rate of anti-SARS-Cov2 seroconversion over 2 months among hospital staff, without any supposed anti-Covid treatment 19.

NCT ID: NCT04386551 Completed - Sars-CoV2 Clinical Trials

Detection of COVID-19 in Saliva Collection

SALICOV
Start date: May 6, 2020
Phase:
Study type: Observational

Since December 2019, the world has faced a pandemic of COVID-19, an infectious disease caused by SARS-CoV-2, a virus that emerged in China. The reference diagnosis is based on the search for the SARS-COV-2 genome in the nasopharyngeal sample. Carrying out this sample requires the competence of a healthcare professional and presents some inconveniences for the tested patient. Because saliva collection is simple, non-invasive, painless and inexpensive, and can be performed by poorly trained personnel, it could be an alternative to the reference nasopharyngeal sample. SARS-CoV2 detection in human saliva could be a potential diagnosis of COVID infection.