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SARS-CoV-2 clinical trials

View clinical trials related to SARS-CoV-2.

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NCT ID: NCT06199934 Active, not recruiting - SARS-CoV-2 Clinical Trials

Effectiveness of BNT162b2 Formulations Using State Vaccine Registry and Insurance Claims Data

Start date: February 7, 2024
Phase:
Study type: Observational

The primary purpose of this study is to learn about how well different versions of the Pfizer-BioNTech COVID-19 vaccine (called BNT162b2) work at preventing death, severe COVID-19 that requires a trip to the hospital, and overall use of healthcare resources, such as needing to go the doctor or urgent care due to illness. Pfizer is not enrolling any participants for this study. Instead, existing data from different health data sources will be used to help answer the scientific questions Pfizer is interested in learning more about.

NCT ID: NCT06130410 Active, not recruiting - COVID-19 Clinical Trials

Special Investigation for Booster Dose of Comirnaty in Children Ages 6 Months Though 4 Years

Start date: March 6, 2024
Phase:
Study type: Observational

The purpose of this post-marketing study is to assess the safety of Comirnaty monovalent XBB.1.5. for booster vaccination children ages 6 months though 4 years under actual use medical practice.

NCT ID: NCT06130345 Active, not recruiting - SARS-CoV-2 Clinical Trials

Post-marketing Safety of Elasomeran/Davesomeran and Andusomeran

Start date: April 14, 2023
Phase:
Study type: Observational

The main objective of the study is to evaluate the safety of the elasomeran/davesomeran and andusomeran vaccines as used in routine clinical practice.

NCT ID: NCT06097273 Active, not recruiting - Influenza Clinical Trials

A Study of mRNA-1083 (SARS-CoV-2 and Influenza) Vaccine in Healthy Adult Participants, ≥50 Years of Age

Start date: October 19, 2023
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the immunogenicity, safety, and reactogenicity of mRNA-1083 as compared with active control, co-administered licensed influenza and severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) vaccines, in 2 independent age-group sub-study cohorts, healthy adults 65 years and older (Cohort A) and healthy adults 50 to <65 years of age (Cohort B).

NCT ID: NCT06039449 Active, not recruiting - COVID-19 Clinical Trials

A Study to Investigate the Prevention of COVID-19 withVYD222 in Adults With Immune Compromise and in Participants Aged 12 Years or Older Who Are at Risk of Exposure to SARS-CoV-2

Start date: September 8, 2023
Phase: Phase 3
Study type: Interventional

A study to investigate the prevention of COVID-19 with VYD222 in adults with immune compromise and in participants aged 12 years or older who are at risk of exposure to SARS-CoV-2

NCT ID: NCT05960097 Active, not recruiting - SARS-CoV-2 Clinical Trials

A Study on the Safety and Immune Response of Investigational COVID-19 mRNA Vaccines in Healthy Adults

Start date: August 1, 2023
Phase: Phase 2
Study type: Interventional

The purpose of Part A of this study is to assess the immune response and safety of a booster dose of investigational COVID-19 mRNA vaccines in healthy adults. The study will compare the investigational vaccines to control vaccine. The purpose of Part B of this study is to assess the immune response and safety of a booster dose of investigational COVID-19 mRNA vaccines in healthy adults. The study will compare the investigational vaccine under three different storage conditions.

NCT ID: NCT05939648 Active, not recruiting - SARS-CoV-2 Clinical Trials

A Phase II Clinical Trial to Evaluate the Immunogenicity and Safety of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021)

Start date: October 9, 2023
Phase: Phase 2
Study type: Interventional

This trial is a phase II clinical trial of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021). The trial was randomized, blinded, placebo controlled. To evaluate the safety and immunogenicity of the study vaccine in participants aged 18 years and older who have received SARS-CoV-2 Vaccine.

NCT ID: NCT05939596 Active, not recruiting - SARS-CoV-2 Clinical Trials

A Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Immunogenicity of SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021)

Start date: August 10, 2023
Phase: Phase 1
Study type: Interventional

This trial is a phase I clinical trial of a SARS-CoV-2 Bivalent mRNA Vaccine (LVRNA021). The trial used a randomized, blinded, placebo-controlled design to evaluate the safety, tolerability, and preliminary immunogenicity of the trial vaccine in participants Aged 18 Years and Older who had received SARS-CoV-2 Vaccine.

NCT ID: NCT05938075 Active, not recruiting - SARS-CoV-2 Clinical Trials

Study of VXCO-100, a SARS-CoV Candidate Vaccine, in Adults in the Republic of South Africa

Start date: August 4, 2023
Phase: Phase 1
Study type: Interventional

The purpose of this study is to evaluate the safety and immunogenicity of ascending dose levels of VXCO-100 in adults.

NCT ID: NCT05933304 Active, not recruiting - COVID-19 Clinical Trials

A Study of the Effectiveness of Moderna COVID-19 Vaccine

Start date: December 18, 2020
Phase:
Study type: Observational

This is an observational cohort study to evaluate real-world vaccine effectiveness and durability of Moderna COVID-19 vaccine among a diverse population at Kaiser Permanente Southern California (KPSC). The primary objective of this study is to evaluate the vaccine effectiveness (VE) of receipt of Moderna COVID-19 vaccine in preventing SARS-CoV-2 infection and severe COVID-19 disease. SARS-CoV-2 infection will be defined as a positive antigen test result as well as a positive molecular diagnostic test among symptomatic or asymptomatic participants or a COVID-19 diagnosis code. Severe COVID-19 disease will be defined as COVID-19 hospitalization or mortality.