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SARS-CoV-2 clinical trials

View clinical trials related to SARS-CoV-2.

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NCT ID: NCT06458504 Not yet recruiting - SARS-CoV-2 Clinical Trials

Viral Infection of HSPC Impacts Hematopoiesis

MEGAHOST
Start date: June 2024
Phase:
Study type: Observational

We propose to demonstrate that HIV-1 and SARS-CoV-2 are capable of targeting long-lived HSPC with self-renewal capacities. These progenitors, thus transformed into host cells, can give rise to a durable source of infected cells with an impact on hematopoiesis.

NCT ID: NCT06167915 Not yet recruiting - SARS-CoV-2 Clinical Trials

Safety and Immunogenicity of Recombinant COVID-19 Trivalent Protein Vaccine (CHO Cell)LYB002V14 in Booster Vaccination

Start date: December 26, 2023
Phase: Phase 1
Study type: Interventional

This is a randomized, blinded, and dose escalation phase I trial in males and non-pregnant females, starting at 18 years of age, inclusive, who are in good health and meet all eligibility criteria. This clinical trial is designed to assess the safety and immunogenicity of Recombinant COVID-19 Trivalent (XBB.1+BQ.1.1+Prototype) Protein Vaccine (CHO Cell)(LYB002V14).

NCT ID: NCT05947812 Not yet recruiting - SARS-CoV-2 Clinical Trials

A Clinical Evaluation of the Safety and Efficacy of Randomized Placebo Versus the 8-aminoquinoline Tafenoquine for Early Symptom Resolution in Patients With Mild to Moderate COVID 19 Disease and Low Risk of Disease Progression

Start date: August 1, 2023
Phase: Phase 2
Study type: Interventional

A clinical study to assess the efficacy and safety of oral tafenoquine compared to placebo in patients with mild to moderate COVID 19 disease and low risk of disease progression (the "ACLR8-LR" study).

NCT ID: NCT05787444 Not yet recruiting - SARS-CoV-2 Clinical Trials

Clinical Validation of the LumiraDx SARS-CoV-2 & Flu A/B Test in Detecting and Differentiating Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), Influenza A (Flu A), and/or Influenza B (Flu B)

Start date: May 1, 2023
Phase:
Study type: Observational

This is a prospective multicenter study conducted to evaluate the performance of the LumiraDx SARS-CoV-2 & Flu A/B tests at point of care sites. Subjects presenting with symptoms suggestive of coronavirus disease 2019 (COVID-19) and Influenza at the time of the study visit will be enrolled and asked to donate swab sample(s) for testing on the device under evaluation.

NCT ID: NCT05599802 Not yet recruiting - SARS-CoV-2 Clinical Trials

Clinical Study of SARS-CoV-2 Variant mRNA Vaccine in Healthy Participants

Start date: February 2023
Phase: Phase 1
Study type: Interventional

An Open-Label, Phase 1 Clinical Study to Determine the Safety and Preliminary Immunogenicity of SARS-CoV-2 Variant mRNA Vaccine (LVRNA010)

NCT ID: NCT05549206 Not yet recruiting - SARS-CoV-2 Clinical Trials

A Cohort Study of SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine in Participants Aged 18 Years and Over in Chinese People

Start date: April 2023
Phase: N/A
Study type: Interventional

This is a cohort study to evaluate safety and immunogenicity of SARS-CoV-2 Variant (Omicron BA.5) mRNA Vaccine (LVRNA012) in participants aged 18 years and over in China

NCT ID: NCT05433181 Not yet recruiting - SARS-CoV-2 Clinical Trials

ACE2 Chewing Gum on SARS-CoV-2 Viral Load (COVID 19)

Start date: February 2025
Phase: Phase 1/Phase 2
Study type: Interventional

A randomized double-blind, placebo controlled clinical trial of the safety, tolerability, and antiviral activity of angiotensin-converting enzyme 2 (ACE2) chewing gum over a 3-day period in non-hospitalized subjects with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection.

NCT ID: NCT05428592 Not yet recruiting - SARS-CoV-2 Clinical Trials

Clinical Trial of SARS-CoV-2 mRNA Vaccine(LVRNA009) as Heterologous Booster in Islamabad

Start date: April 2023
Phase: Phase 3
Study type: Interventional

This study is a randomized, blinded, parallel-controlled phase 3 clinical trial. The study intent to evaluate the immunogenicity and safety of SARS-CoV-2 mRNA Vaccine (LVRNA009) as heterologous booster in participants aged 18 years and older vaccinated 2 doses Inactivated SARS-CoV-2 Vaccine.

NCT ID: NCT05222425 Not yet recruiting - Sars-cov-2 Clinical Trials

Treatment of Non-severe Covid-19 Outpatients With Xagrotin, Phase 3

Start date: June 1, 2022
Phase: Phase 3
Study type: Interventional

This is an interventional, multi-center, randomized study. Adults with confirmed covid-19 disease not more than 10 days before enrollment date will be recruited (n=1000). Patients in same condition who get treated with standard of care will be randomly assigned to the control group (n=1000), and patients in same condition who get treated with standard of care will be randomly assigned to the placebo group (n=1000). The investigators analyze the effect of Xagrotin, and also investigate impact of different characteristics for instance gender, age, duration of disease, smoking habits and concomitant diseases on the outcome.

NCT ID: NCT04709328 Not yet recruiting - COVID-19 Clinical Trials

To Evaluate SCTA01 Treatment of High-risk Outpatients With COVID-19

MAOP3
Start date: March 28, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

The study is a multicenter, adaptive, randomized, double-blinded and placebo-controlled Phase II/III clinical trial. It will be conducted at selected investigational sites globally. The study is comprised of 2 parts.