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Rupture clinical trials

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NCT ID: NCT05717270 Recruiting - Clinical trials for Achilles Tendon Rupture

Two-layer Suturing of Achilles Tendon Ruptures

ATRBFH
Start date: May 23, 2023
Phase:
Study type: Observational [Patient Registry]

The purpose of the present study is to measure whether a new technique of double row suturing of a ruptured Achilles tendon will result in a normalization of the length of the Soleus part (primary outcome) and of the superficial Gastrocnemius part of the tendon (secondary outcome) one-week post-operative. Results will be compared to that of a participants group that underwent the same operation but with a standard operative technique and the same rehabilitation regime recently completed (NCT04263493). The investigators hypothesize that the new suturing technique will result in an elongation of the Soleus part of the Achilles tendon (primary outcome) by 8.9 mm or less relative to the uninjured contralateral side one week (primary endpoint) after surgery compared to retrospective data from a recently completed randomized controlled trial

NCT ID: NCT05683080 Recruiting - Clinical trials for Achilles Tendon Rupture

Impact of Achilles Tendon Rupture on the Achilles Tendon and Calf Muscles

ARCH
Start date: May 24, 2023
Phase:
Study type: Observational

The aim of this study is to measure the recovery following Achilles tendon rupture. The investigators will use an ultrasound scan to look at the Achilles tendon, they will complete calf strength tests and use questionnaires to measure how individuals are managing in everyday life. The investigators will take these measurements when participants first arrive to the Achilles tendon rupture clinic, after 8 weeks, 10 weeks, 4 months, 6 months and 1 year.

NCT ID: NCT05682820 Recruiting - Clinical trials for Anterior Cruciate Ligament Injuries

Analysis of Radiological Features of Lateral Femoral Impaction Fracture / Lateral Femoral Notch Sign

Start date: June 3, 2020
Phase:
Study type: Observational

Analysis of Radiological Features of Lateral Femoral Impaction Fracture (LFC-IF) / Lateral Femoral Notch Sign will be performed on MRIs of consecutive patients after anterior cruciate ligament (ACL) injuries and without ACL injuries.

NCT ID: NCT05673356 Recruiting - Clinical trials for Anterior Cruciate Ligament Injuries

Anterior Cruciate Ligament Reconstruction With Quadriceps Tendon Bone Autograft

Start date: August 28, 2020
Phase: N/A
Study type: Interventional

Anterior cruciate ligament injuries are one of the most common sports knee injuries. Their effect on the knee joint can be detrimental with patients experiencing instability and progressive damage of the intraarticular structures. Therefore, anterior cruciate ligament reconstruction (ACLR) is often indicated. Multiple graft option exist, including autograft, allograft and xenograft tissues, with autografts being considered as a first-choice source of reconstructed ligament in most cases. Two most common harvested autografts are hamstring tendons (semitendinosus or semitendinosus and gracilis tendons; ST or STG) and patellar tendon with two bone blocks (bone - patellar tendon - bone; BPTB). However, in the recent literature there is an increasing trend towards use of quadriceps tendon autograft (QT). Multiple techniques of harvesting this graft were described, including both partial and complete thickness of the tendon. Another issue is whether bone block from the upper pole of the patella is harvested along with the soft tissues (quadriceps tendon bone graft, QTB). The aim of this study is to add to the body of knowledge concerning full-thickness quadriceps tendon-bone autograft (QTB) used in ACLR. The primary outcome consists of The International Knee Documentation Committee Questionnaire (IKDC), the Knee injury and Osteoarthritis Outcome Score (KOOS) and retear rate.

NCT ID: NCT05643079 Recruiting - Clinical trials for Flexor Tendon Rupture

Medial Displacement Calcaneal Osteotomy and FDL- Transfer - With a Human, Allogeneic Cortical Bone Screw

Start date: February 10, 2022
Phase:
Study type: Observational

The goal of this observational study is to compare the use of a screw made of human bone (Shark-Screw®, Surgebright-GmbH) with the metal/Bio-Tenodesis screw (Arthrex) in the treatment of the symptomatic flatfoot using the medializing calcaneus osteotomy with flexor digitorum longus transfer (FDL) in adult patients. The advantage of the human bone screw is that after surgery no hardware removal is necessary. The screw is transformed from the body to normal bone. The main questions it aims to answer are: - Can the human bone screw achieve union rates like the metal/Bio-Tenodesis screw? - Is the time to union similar between the different screws? - Is the complication rate similar between the different screws? - Are the activity scores American Orthopaedic Foot and Ankle Society (AOFAS), Foot and Ankle Outcome Score (FAOS) and Foot Function Index (FFI) after surgery similar in the compared patient groups? Participants will have - the surgery - follow-ups at 6 weeks, 6 months, 1 and 2 years. - X-rays are performed at each follow up. - CT-scans are performed after 6 months. - activity scores are collected at the follow up after 6 months, 1 year and 2 years.

NCT ID: NCT05617092 Recruiting - Clinical trials for Pelvic Floor Disorders

The Effect of a Postpartum Training Program on Women Who Have Suffered a Levator Ani Injury.

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

The goal of this pilot randomized pilot controlled trial (RTC)is to collect acceptability and feasibility outcomes of a physiotherapy individualized program in women with levator injury that is intended to be used in a larger scale multicenter randomized controlled trial (RTC) in the future. The main questions it aims to answer are if a physiotherapy program in women with a levator injury: 1. Can improve the pelvic floor morphometry (PFM). 2. Can improve urogynecological symptoms 3. The effect of a physiotherapy program in the sexual function 4. The effect of a physiotherapy program in the patient's fear avoidance beliefs about physical activity and work Type of study: randomized pilot controlled trial (RTC) The design of this trial will be a pilot randomized controlled trial with 3 arms. Participants will be randomized in 2 arm of women with levator ani injury to either physiotherapy or standard care and an arm of woman without levator injury Researchers will compare the 3 groups to see if a physiotherapy program have benefits in morphometry of the pelvic floor, urogynecological symptoms, sexual function and to avoid fear avoidance beliefs about physical activity and work.

NCT ID: NCT05585528 Recruiting - Ligament Rupture Clinical Trials

Informing the Patient on the Type of Management, Surgical or Functional, After Rupture of the Anterior Cruciate Ligament

INFO-LCA
Start date: December 20, 2022
Phase: N/A
Study type: Interventional

The purpose of the study is to evaluate the proportion of patients after rupture of the anterior cruciate ligament (ACL) of the knee, who will have functional or surgical management (PEC) in 1st intention, after having received appropriate information.

NCT ID: NCT05579067 Recruiting - Clinical trials for Anterior Cruciate Ligament Injuries

Comparative Evaluation of Functional Results and Survival Rate of Peroneus Longus Tendon - PLT and Hamstring Tendon - HT Used for Reconstruction of the Anterior Cruciate Ligament.

Start date: February 2, 2022
Phase: N/A
Study type: Interventional

Comparative evaluation of functional results and survival rate of peroneus longus tendon - PLT and hamstring tendon - HT used for reconstruction of the anterior cruciate ligament.

NCT ID: NCT05573347 Recruiting - Clinical trials for Rotator Cuff Tear or Rupture, Not Specified as Traumatic

Cellular Content of Bone Marrow Aspiration, Comparison

BioCuff
Start date: August 16, 2022
Phase:
Study type: Observational

The goal of this observational clinical trial is to determine whether the posterior superior iliac spine of the hip or the humerus of the arm will produce larger amounts of bone marrow when harvested during surgery. Also, the secondary goal of this study is to determine the effects of the patient's position on the quantity of cells harvested from the hip, namely lying on back (prone) vs. lying on side (lateral decubitus). The main questions it aims to answer are: - Will the hip or the arm have more bone marrow extracted? - Does a patient lying in lateral decubitus position produce more bone marrow than lying in the prone position? Participants that are to undergo rotator-cuff repair are eligible for this study. During the participant's repair, bone marrow will be extracted from the arm and from the hip. Half of the eligible participants will have bone marrow extracted from the hip while lying on their side, while the other half will have bone marrow extracted from the hip while lying on their back. Researchers will compare the results from both extraction sites on each patient, as well as compare results of the two patient position groups.

NCT ID: NCT05568745 Recruiting - Induction of Labor Clinical Trials

Balloon + Oxytocin Versus Oral Misoprostol to Induce Labor in Case of PROM (RUBAPRO2)

RUBAPRO2
Start date: January 18, 2023
Phase: Phase 4
Study type: Interventional

Premature rupture of membranes (PROM) at term complicates 6 to 22% of singleton pregnancies. Spontaneous labour occurs in 60-67% of these patients within 24h. If no effective uterine contraction occurs, induction of labour (IOL) is the strategy recommended by the French as well as the American College of Obstetricians and Gynecologists. The optimal strategy for IOL in case of PROM with an unfavourable cervix remains unknown and none of the studies conducted in nulliparous women showed the superiority of one induction method over another. In the current project, we aimed to determine (1) if IOL with association of balloon catheter and oxytocin after 6 hours could increase the rate of delivery < 24h versus low dose of oral misoprostol (25 µg oral PGE1 every 2h) in case of PROM at term in nulliparous women and (2) patient satisfaction using EXIT survey assessed before hospital discharge.