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Rupture clinical trials

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NCT ID: NCT06343480 Completed - Clinical trials for Labor Onset and Length Abnormalities

Misoprostol Versus Oxytocin for Induction of Labour in Parturients With Spontaneous Rupture of Fetal Membranes at Term

Start date: September 1, 2020
Phase: N/A
Study type: Interventional

Intravenous oxytocin titration has a prime position as a choice agent for induction of labour following term PROM as it has been shown to be efficacious for such purpose. Recent evidence however has shown that misoprostol is associated with better outcomes and merits evaluation in our environment. This study compared the efficacy of misoprostol and oxytocin for induction of labour in parturients with term Prelabour Ruptuture of Membranes.

NCT ID: NCT06198582 Completed - Clinical trials for Tendon Injury - Hand

The Effect of Virtual Reality Based Task Specific Exercises in Patients With Hand Flexor Tendon Injury

Start date: June 1, 2021
Phase: N/A
Study type: Interventional

This study,the investigators aimed to investigate the effects of virtual reality-based task-specific exercises applied in addition to conventional rehabilitation program on functional level and disease-related quality of life in patients who underwent surgical repair due to flexor tendon damage due to traumatic hand injury.

NCT ID: NCT06102278 Completed - Clinical trials for Peritoneal Metastasis

ML Models for Predicting Postoperative Peritoneal Metastasis After Hepatocellular Carcinoma Rupture

Start date: January 1, 2020
Phase:
Study type: Observational

This study aimed to address the issue of peritoneal metastasis (PM) following the rupture of hepatocellular carcinoma (HCC) and its adverse impact on patient prognosis. Clinical data from 522 patients with ruptured HCC who underwent surgery at seven different medical centers were collected and analyzed. Machine learning models were employed for analysis and prediction.

NCT ID: NCT06004297 Completed - ACL Injury Clinical Trials

Influence of Combined Double-Bundle ACL Reconstruction With Lateral Retinacular Release to Prevent Patellofemoral Malalignment in Isolated ACL Rupture

Start date: January 7, 2019
Phase: N/A
Study type: Interventional

Anterior knee pain which might be due to patellofemoral malalignment is an inevitable post operative complication after an ACL reconstruction (ACLR). We combined the double bundle ACLR technique with lateral release technique to prevent patellofemoral malalignment post ACLR.

NCT ID: NCT05876013 Completed - Surgery Clinical Trials

Reduced Knee Flexion Strength 18 Years After ACL Reconstruction in Hamstring Group Compared to Patellar Tendon Group

Studie ACL
Start date: March 14, 2022
Phase:
Study type: Observational

Background: Bone-patellar tendon-bone (BPTB) and a double-looped semitendinosus gracilis (hamstring group) graft are commonly used for ACL reconstruction. Short-term and mid-term studies show little to no significant difference between the two groups, and there are a few long term studies to compare results between the two grafts. Purpose: To compare the results after using either BPTB grafts or hamstring grafts 18 years after ACL reconstruction. Study design: Randomized controlled trial; Level of evidence II. Methods: 114 patients with ACL rupture between 2001 and 2004 were randomized to reconstruction with either BPTB graft or a hamstring graft. Patients were operated at four major hospitals. The 18-year follow-up evaluation included isokinetic testing of muscle strength, patient-reported outcome measures, clinical knee examination and an assessment of radiological osteoarthritis using the Kellgren-Lawrence classification. Hypothesis:Hypothesis is that there will be no difference in the long-term outcome between the two groups, as well hypothesis of no difference in patients with prosthesis after ACL reconstruction, arthrosis difference in operated knees and the rate of graft failure between the two groups. Previous follow-up studies showed a significant difference in total flexion work between the two groups, so detecting a persistent difference between the groups will be point of interest.

NCT ID: NCT05809102 Completed - Clinical trials for Flexor Tendon Rupture

Repair Of Flexor Tendon In Zone II Using Minimal Incisions

Start date: February 1, 2020
Phase: N/A
Study type: Interventional

Repair of the zone II flexor tendon of the hand using minimal incisions is successful with good results which will improve the outcome of the repair.

NCT ID: NCT05785520 Completed - Clinical trials for Long Head of Biceps Rupture

Evaluation of the "ST500 SINGLE- DOSE GEL" in Patients With Symptomatic Long Head of the Biceps Tendon Injury

Start date: November 30, 2021
Phase: N/A
Study type: Interventional

Single arm, post-market, confirmatory, interventional clinical investigation - Medical Device

NCT ID: NCT05755841 Completed - Clinical trials for Management of Preterm Prelabor Rupture of Membranes

Outpatient Management of Preterm Prelabor Rupture of Membranes

Start date: March 1, 2022
Phase:
Study type: Observational

Home-care management is possible if patients are clinically stable forty-eight hours after Preterm Prelabour Rupture of the membrane with no clinical or biological signs suggestive of intrauterine infection. Several retrospective studies have highlighted the safety of such outpatient management for women with nonthreatening Preterm Prelabour Rupture of the membrane. This prospective cohort study will compare inpatient versus outpatient management of preterm Prelabour rupture of membrane regarding latency, intra-amniotic infection, birth weight, and neonatal complications at 28 to 34 weeks of gestation after 48 hours of admission to Ain-Shams University Maternity Hospital.

NCT ID: NCT05529511 Completed - Rehabilitation Clinical Trials

The POP-ACLR Study

POP-ACLR
Start date: August 3, 2022
Phase:
Study type: Observational

The anterior cruciate ligament is one of four key ligaments in the knee. It is the most commonly injured knee ligament with an estimated 200,000 injuries occurring each year in the US (UK data unavailable). Surgery is currently standard treatment for this injury and helps patients return to work and their preinjury activity levels (such as running, playing football or netball). Patients expect surgery to be successful. However, the number of patients who are able to return to their normal activities is low, with only 24% returning at 1 year after surgery. Research has shown that after surgery, patients lack confidence, feel fearful about reinjuring their knee and need to continue to seek advice from healthcare professionals. Receiving physiotherapy before surgery (called 'prehabilitation') is recommended by researchers and physiotherapists to help patients prepare for surgery and postoperative rehabilitation. Although physiotherapy is recommended, some patients don't receive any treatment before their operation, but it is not known why this might be. There are also no guidelines for the treatment patients receive and current treatment varies. If an intervention to be delivered to patients prior to anterior cruciate ligament surgery (prehabilitation treatment package) is developed, patient care may be improved. Patient outcomes could also be improved resulting in more patients returning to physical activity after surgery. This study will firstly, interview participants at three different time points along the patient pathway (1) 12 participants up to 2 weeks before surgery, (2) 12 participants 3 months after surgery, (3) 12 participants 12 months after surgery. The interviews will allow participants to tell the story of their experiences from the point of receiving their injury diagnosis to returning to physical activity and what they expect from their surgery. Secondly, the prehabilitation treatment package will be designed with healthcare professionals, therapy managers and patients.

NCT ID: NCT05464485 Completed - Clinical trials for Anterior Cruciate Ligament Rupture

Hamstring Muscle Strength After ACL Hamstring Reconstruction

HAMSTRING
Start date: January 1, 2017
Phase:
Study type: Observational

Anterior Cruciate Ligament (ACL) reconstructions using hamstring grafts can be performed using one or two hamstring grafts, the semitendinosus (ST) tendon only, or both the semitendinosus and gracilis (ST/G) tendon. As most patients strive to return to sport nine months after reconstruction the purpose of this study was to compare the recovery of hamstring muscle strength during these first nine months after reconstruction using the ST or ST/G tendons.