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Rupture clinical trials

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NCT ID: NCT05676632 Not yet recruiting - Clinical trials for Achilles Tendon Rupture

Impact of Achilles Tendon Ruptures: Cross-Sectional Analysis

Start date: May 1, 2023
Phase:
Study type: Observational

This project will assess the clinical outcomes of individuals completing rehabilitation for their Achilles tendon rupture at the University Hospitals of Leicester. Patients attending the Achilles tendon rupture clinic or rehabilitation classes will be asked to complete ultrasound imaging, strength testing and questionnaires. This will provide an insight into the rehabilitation outcomes of a broad range of patients at each rehabilitation timepoint.

NCT ID: NCT05576727 Not yet recruiting - Clinical trials for Intracranial Aneurysm

Prediction of Development and Rupture Risk for Intracranial Unruptured Aneurysms

Start date: January 1, 2023
Phase:
Study type: Observational

In recent years, researches on the natural history and risk factors of intracranial unruptured aneurysms have become a hot topic at home and abroad. However, risk factors for aneurysm rupture is still unclear yet. The investigators' preliminary study focused on constructing a rupture risk prediction system for intracranial unruptured aneurysm in the investigators' single center. The investigators' result showed that three significant factors (sex, abnormal serum tumor necrosis factor (TNF)-α and coincidence of thin-walled regions (TWR) and normalized wall shear stress (NWSS)) stood out by using logistic regression to explore the rupture risk factors of intracranial unruptured aneurysms, which could help guide the clinical treatment of intracranial unruptured aneurysms. This study is to evaluate and improve the rupture predict model of intracranial unruptured aneurysm in multi-neurosurgical centers.

NCT ID: NCT05575570 Not yet recruiting - Clinical trials for Abdominal Aortic Aneurysm Without Rupture

Pre-emptive Abdominal Aortic Aneurysm Sac Embolization During EVAR

Start date: November 1, 2024
Phase: N/A
Study type: Interventional

Pre-emptive abdominal aortic aneurysm sac embolization during endovascular abdominal aortic repair for infrarenal abdominal aortic aneurysm - Randomized study

NCT ID: NCT05556304 Not yet recruiting - Perineal Tear Clinical Trials

In Vivo Evaluation of Perineal Mechanical Properties During Childbirth

MecaPer
Start date: October 1, 2022
Phase: N/A
Study type: Interventional

The objective of this work is to evaluate perineal elasticity and deformation and the perineal stresses induced by the fetus during delivery.

NCT ID: NCT05510310 Not yet recruiting - Clinical trials for Labor Onset and Length Abnormalities

Breast Stimulation vs. Low Dose Oxytocin Augmentation for Labor Induction

Start date: October 2022
Phase: Phase 1/Phase 2
Study type: Interventional

To find the preferred method of labor induction (birth augmentation) for women with a history of one prior cesarean section scar and in grandmultiparas, the difference in time interval from augmentation to delivery will be measured between breast stimulation vs. low-dose oxytocin administration in this prospective single-center randomized controlled trial.

NCT ID: NCT05500872 Not yet recruiting - Clinical trials for Anterior Cruciate Ligament Rupture

Blood Flow Restriction After Anterior Cruciate Ligament Reconstruction (ACLR)

ACLR
Start date: August 30, 2022
Phase: N/A
Study type: Interventional

Muscle strength and muscle volume decrease rapidly with the immobilization process after sports-related injury and surgery. Depending on the decrease in muscle strength and muscle volume, functional performance also deteriorates, and this has been demonstrated by studies in the literature. Despite rehabilitation programs after anterior cruciate ligament surgery, muscle weakness persists for a long time and this affects knee functions. As a result, the time to return to sports is delayed or the activity level decreases. In recent studies, cross training is used to gain strength. Cross training is the increase in strength in the untrained leg after unilateral strengthening of the untrained leg. Another popular application for strength gain is exercise training with blood flow restriction. Blood flow restriction exercise training is an exercise protocol based on external pressure restriction of blood flow through the cuff from the proximal of the target muscle. It has been shown that this training prevents reduction of muscle volume in the early postoperative period and increases muscle strength. In the literature, cross-training and blood flow-restricted training are applied separately for muscle strength development after ACL reconstruction. However, no study investigating the effect of the combined application of these two approaches on muscle strength during ACL rehabilitation has been found. It is thought that with the combined application of these approaches, their effects on muscle strength development will increase, and accordingly, the functional results of individuals will be positively affected. The aim of the study is to determine the effect of cross training applied with and without blood flow restriction on muscle strength and function for 8 weeks starting from the 4th week after anterior cruciate ligament surgery. Participants will be included in the training for a total of 16 sessions, 2 days a week for 8 weeks. Pain, muscle strength, muscle thickness, knee functions will be evaluated before and after the training.

NCT ID: NCT05469984 Not yet recruiting - Clinical trials for Preterm Labor With Preterm Delivery

Comparing Two Prophylactic Antibiotic Protocols in Women With Term Prolonged Pre-labor Rupture of Membrane and Preterm Labor

Start date: September 2022
Phase: N/A
Study type: Interventional

This randomized prospective trial aimed to compare 2 prophylactic antibiotic regiment (ampicillin alone versus ampicillin plus gentamycin) in term prolonged pre-labor rupture of membrane and in preterm deliveries and examine related obstetrical outcome and infectious morbidity

NCT ID: NCT05440890 Not yet recruiting - Clinical trials for Anterior Cruciate Ligament Injuries

Early Treatment Based Neuroscience Education in Knee

ETbNE
Start date: April 1, 2025
Phase: N/A
Study type: Interventional

Determine the effecttiveness of a cross-education strength training protocol in a group of subjects with an anterior cruciate ligament surgery.

NCT ID: NCT05431790 Not yet recruiting - Clinical trials for Anterior Cruciate Ligament Rupture

Absorbable Interface Screw Clinical Trial

Start date: July 30, 2022
Phase: N/A
Study type: Interventional

Validation of the safety and efficacy of absorbable interface screws for clinical use

NCT ID: NCT05430711 Not yet recruiting - Clinical trials for Prelabor Rupture of Membranes

Dinoprostone Induction vs. Expectant Management After PROM at Term

Start date: June 2022
Phase: Phase 4
Study type: Interventional

Prelabour rupture of membranes (PROM) is associated with intrauterine infection and maternal and neonatal consequences. This risk increases with the length of time from PROM to delivery. Induction of labor has been shown to reduce the rates of those complications, however the optimal time interval has not yet been determined. The main purpose of this single-center randomized prospective study is to assess the differences between two approaches of managing PROM at term-expectant management and induction with a dinoprostone vaginal delivery system.