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Rupture clinical trials

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NCT ID: NCT03986749 Completed - Clinical trials for Rotator Cuff Tear or Rupture, Not Specified as Traumatic

Bursa Augmentation in Arthroscopic Rotator Cuff Repair

ARCR-Bursa
Start date: October 1, 2019
Phase: N/A
Study type: Interventional

The aim of this first study is to investigate in a case series through sequential sonographic imaging, using Doppler ultrasonography, the postoperative morphology, especially vascularity and findings of neovascularity, after bursa augmentation in arthroscopic rotator cuff repair.

NCT ID: NCT03984474 Recruiting - Clinical trials for Anterior Cruciate Ligament Rupture

The Clinical Outcome of Anterior Cruciate Ligament Reconstruction

RCACLR
Start date: January 14, 2003
Phase:
Study type: Observational

Retrospective cohort study. The investigators evaluated the early, middle and long term effects of different surgical methods of anterior cruciate ligament reconstruction on knee function. In the evaluation, the investigators focused on the differences between different age groups, different genders and different basic motor states, the differences between early reconstruction and non-early reconstruction, and the differences in clinical outcomes of different surgical methods.

NCT ID: NCT03982940 Active, not recruiting - Clinical trials for Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture

BGP+ Stent as Bridging Stent in BEVAR

Start date: September 9, 2020
Phase: N/A
Study type: Interventional

The objective of this clinical investigation is to evaluate, in a controlled setting, the safety and performance of the BGP+ balloon expandable covered stent Graft System (Bentley InnoMed, Hechingen, Germany) implanted as bridging stent in BEVAR (branched endovascular aortic repair) for complex aortic aneurysms.

NCT ID: NCT03976063 Recruiting - Clinical trials for Preterm Premature Rupture of Membrane

Tocolysis in the Management of Preterm Premature Rupture of Membranes Before 34 Weeks of Gestation

TOCOPROM
Start date: October 7, 2019
Phase: Phase 3
Study type: Interventional

The purpose of this study is to assess whether short-term (48 hr) tocolysis reduces perinatal morti-morbidity in cases of PPROM at 22 to 33 completed weeks' gestation.

NCT ID: NCT03966521 Completed - Clinical trials for Abdominal Aortic Aneurysm Without Rupture

The British Society of Endovascular Therapy ConformabLe EndoVascular Aneurysm Repair Registry

BSET-CLEVAR
Start date: June 26, 2019
Phase:
Study type: Observational [Patient Registry]

The purpose of the BSET-CLEVAR Registry is to collect device-specific performance outcomes of the GORE® EXCLUDER® Conformable AAA Endoprosthesis with ACTIVE CONTROL System (EXCC device) in routine clinical treatment of patients with abdominal aortic aneurysm in the UK. The novel EXCC device is an evolution of an established device allowing active shaping to conform to the specific patient aortic neck anatomy, with more accurate deployment, potentially greater neck coverage and better long term fixation/sealing. This may translate to improved effectiveness of this device over time, reducing the need for any further procedures. The primary aim of this study is to assess the degree of neck coverage by the EXCC device. The British Society of Endovascular Therapy (BSET) has received funds from the stent manufacturer (W.L. Gore & Associates, Inc.) to conduct this study. BSET and the Sponsor (Imperial College London) have full responsibility for the design, conduct, analysis and reporting of the study.

NCT ID: NCT03950024 Recruiting - Clinical trials for Anterior Cruciate Ligament Rupture

Improvement of Knowledge About the Arthrogenic Muscle Inhibition in the Aftermath of Knee Trauma.

CAMIK
Start date: October 29, 2019
Phase: N/A
Study type: Interventional

Arthrogenic Muscle Inhibition (AMI) is one of the classic complications occurring in the aftermath of knee trauma; AMI is grossly defined as a lack of extension due to quadriceps inhibition and hamstring contracture. However, its origins remains unknown with a strong suspicion for a central brain origin. It could be the missing link explaining this lack of extension following an anterior cruciate ligament (ACL) rupture. The primary hypothesis of this study is that a difference in activation of motor brain areas exists in patients with an ACL rupture, between those with AMI or without. The second hypothesis is that this difference could be seen on brain functional MRI.

NCT ID: NCT03931486 Completed - Clinical trials for Achilles Tendon Rupture

Detection of Bacterial DNA and Collagen Metabolism in Acutely Ruptured Achilles Tendons

Start date: May 3, 2019
Phase:
Study type: Observational

The etiology and pathogenesis of acute Achilles tendon ruptures are complex and not fully understood. It is well known that they are associated with pre-existing pathological alterations, similar to the changes observed in tendinopathy. The present study investigates if bacteria and collagen metabolism play a role in the etiology of acute Achilles tendon rupture. During surgery, 20 patients will have taken two biopsies from the ruptured part of the tendon and two biopsies from the healthy tissue of the same tendon 2-4 cm proximal to the rupture, as a control.

NCT ID: NCT03925155 Withdrawn - Clinical trials for Cesarean Section Complications

RCT Investigating Pre-cesarean Vaginal Wash of Chlorhexidine vs Povidone-iodine for Patient With Ruptured Amniotic Membrane.

VAP
Start date: May 1, 2020
Phase: Phase 3
Study type: Interventional

The objective of this study is to investigate if the rate of infectious morbidity is decreased with the use of chlorhexidine or povidone-iodine vaginal scrub before cesarean section after ruptured membranes.

NCT ID: NCT03913611 Recruiting - Rotator Cuff Tear Clinical Trials

Shoulder Surgery Traditional vs Accelerated Rehabilitation Trial

S-START
Start date: October 18, 2019
Phase: N/A
Study type: Interventional

This is a randomised controlled trial involving patients who have a double-row arthroscopic rotator cuff repair. Null hypothesis: There is no difference in outcome between standard rehabilitation and accelerated rehabilitation after arthroscopic rotator cuff repair. Following surgery, they will be randomised to one of two groups: 1. Standard rehabilitation, with enforced sling use for 6 weeks and a structured exercise programme. 2. Accelerated rehabilitation with no requirement to use a sling and a structured exercise programme. The primary outcome measure will be the Oxford Shoulder Score at 6 months. We will also collect data on postoperative pain, range of shoulder movement and other subjective outcome measures. All patients will have MRI scans at 6 months postoperatively to assess the integrity of the repair, allowing comparison of failure rates between groups.

NCT ID: NCT03896464 Recruiting - Clinical trials for ACL - Anterior Cruciate Ligament Rupture

Soft-tissue Quadriceps Autograft ACL-reconstruction in the Skeletally-immature vs. Hamstrings

SQuASH
Start date: January 1, 2020
Phase: N/A
Study type: Interventional

To date, the use of the quadriceps tendon as an autograft option in primary paediatric Anterior Cruciate Ligament (ACL) reconstruction has not been well studied. The 2018 International Olympic Committee (IOC) Consensus Statement now outlines the quadriceps tendon as a possible autograft option. However, no Randomised Control Trial (RCT) has examined the efficacy of the quadriceps tendon autograft in primary paediatric ACL reconstruction compared to the historical "gold-standard" soft-tissue hamstring autograft in this population. In light of its evidence for favourable outcomes in the adult population, and the (albeit limited) evidence showing safety and promise in the paediatric population, clinical equipoise exists for assessing its impact on outcomes in paediatric patients at the index surgery. This trial aims to demonstrate feasibility of a global RCT that will evaluate the efficacy of soft-tissue quadriceps versus hamstring autograft tendons on re-operation, return to sport, and knee function among paediatric patients undergoing primary ACL reconstruction.