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Root Resorption clinical trials

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NCT ID: NCT05232318 Recruiting - Root Resorption Clinical Trials

Root Resorption Accompanied Clear Aligners and Fixed Orthodontic Appliance

Start date: April 1, 2022
Phase: N/A
Study type: Interventional

The aim of the study is to compare apical root resorption accompanied orthodontic treatment using clear aligners vs fixed appliances.

NCT ID: NCT05077878 Completed - Root Resorption Clinical Trials

Analysis of Dentine Sialophosphoprotein (DSPP) for Root Resorption

Start date: September 14, 2018
Phase:
Study type: Observational

This study was conducted after obtaining approval from UKM Research Ethics Committee. Gingival Crevicular Fluid (GCF) from Orthodontic and non-orthodontic patients was collected with the consent of patients to detect Dentine sialophosphoprotein. Spectrometry analysis of Gingival Crevicular Fluid was conducted in collaboration with MIMOS Berhad.

NCT ID: NCT04870463 Recruiting - Clinical trials for Apical Root Resorption

Apical External Root Resorption Secondary to Orthodontic Forces and Individual Radicular Stress

Start date: September 13, 2021
Phase: N/A
Study type: Interventional

The goal of this prospective clinical trial is to evaluate the possible superiority of a treatment compared to the gold standard of reference in Orthodontics.

NCT ID: NCT04825665 Completed - Root Resorption Clinical Trials

The Effect of Two Different Types of Forces on Possible Root Resorption in Relation to Dentin Phosphoprotein Levels

Start date: March 17, 2020
Phase: N/A
Study type: Interventional

External root resorption is a common unfavourable sequel of orthodontic treatment. Although diagnosis of root resorption is usually done by radiographs; they are technique sensitive. Dentine phosphoprotein, a non-collagenous protein, is suggested to be released into the gingival crevicular fluid during active root resorption, serving as a good diagnostic tool. Also, the manner of force application is a modifiable factor suggested to affect root resorption.

NCT ID: NCT04823325 Completed - Clinical trials for Class III Malocclusion

Determining the Presence of RAP in Orthognathic Patients and Its Effect on Root Resorption by Biomarkers

RAP
Start date: January 5, 2019
Phase:
Study type: Observational

A prospective clinical trial to what extent inflammatory biomarkers are affected by the medication after orthognathic surgery in early surgical cases and whether these biomarkers affects the amount of maxillary or mandibular incisor root resorption.

NCT ID: NCT04686617 Completed - Vibration; Exposure Clinical Trials

Effect of Mechanical Vibration on Root Resorption

Start date: September 1, 2013
Phase: N/A
Study type: Interventional

The aim of this study was to investigate the effect of mechanical vibration on root resorption with or without the application of orthodontic force. Twenty patients who required maxillary premolar extractions as part of their orthodontic treatment were randomly separated into two groups of 10: no-force group and force group. Using a split-mouth procedure, each patient's maxillary first premolar teeth were randomly assigned as either vibration or control side in both groups. Buccally directed vibration of 113 Hz, using an Oral-B HummingBird device with a modified tip, was applied to the maxillary first premolar for 10 mins/day during 12 weeks. After the force application period, the maxillary first premolars were extracted and scanned with micro-computed tomography. Fiji(ImageJ) which made slice-by-slice quantitative volumetric measurements was used for resorption crater calculation. Total crater volumes was compared with Wilcoxon and Mann-Whitney U tests.

NCT ID: NCT04669392 Not yet recruiting - Pain Clinical Trials

The Effect of Using 70% Ethanol Alcohol as a Root Canal Irrigant on Increasing the Success Rate of Metapex in Pulpectomy Compared to Normal Saline in Primary Molars

Start date: December 1, 2021
Phase: Early Phase 1
Study type: Interventional

The aim of the study is to perform a clinical and radiographic evaluation of 70% Ethanol Alcohol versus Normal Saline as root canal irrigating solutions in partial pulpectomy of primary molars with Metapex.

NCT ID: NCT04601662 Completed - Clinical trials for Crowding of Anterior Mandibular Teeth

Evaluation of the Root Resorption and Dehiscence Formation Between Two Methods of Leveling and Alignment of Lower Teeth

Start date: March 15, 2017
Phase: N/A
Study type: Interventional

The duration of orthodontic treatment is one of the exacerbation causes of orthodontic pain. Several methods have been suggested to reduce the duration of orthodontic treatment classified to surgical and non-surgical methods. Researchers used minimally invasive surgical methods like corticision, piezocision, micro-osteoperforation, and piezopuncture indicated that most of these methods can accelerate dental movement by 20 - 40%. The effect of corticision as a minimally invasive procedure on root resorption and dehiscence formation during orthodontic tooth movement has not been studied yet. Applying corticision on the lower anterior teeth using a surgical blade and a hammer may accelerate tooth alignment during orthodontic treatment. This study consists of two groups, patients will be randomly assigned to one of these two groups.

NCT ID: NCT04410679 Completed - Root Resorption Clinical Trials

Treatment of Internal Inflammatory Root Resorption Using Injectable PRF Revascularization Technque

Start date: June 3, 2018
Phase: N/A
Study type: Interventional

Currently Endodontics looks forward for regeneration rather than repair. Regenerative endodontic therapy was limited to pulp revascularization of necrotic pulp in immature teeth , followed by mature teeth. Recently pulp revascularization technique by induction of blood clot was applied in the treatment of inflammatory root resorption. So far, no clinical study for management of teeth with inflammatory internal root resorption by using injectable PRF revascularization has been described in the literature. Thus, this is the first clinical attempt to manage inflammatory root resorption in necrotic incisor teeth using injectable PRF regenerative approach.

NCT ID: NCT04291443 Completed - Clinical trials for Orthodontic Appliance Complication

Proteomics and Orthodontic Root Resorption

Start date: March 1, 2019
Phase: N/A
Study type: Interventional

The majority of previous studies for early detection of Orthodontically Induced Inflammatory Root Resorption (OIIRR) were conducted to assess individual biomarkers which are representative of single biological pathway. To our Knowledge, no studies have been employed Gingival crevicular fluid (GCF) proteomic analysis to identify potential biomarkers for OIIRR. Therefore; the aim of this study is to use the advantage of testing a package of biomarkers via doing proteomic analysis of GCF which could help in making a more precise personalize diagnosis and treatments, thereby providing orthodontists additional information that cannot be deduced from clinical parameters.