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Rhinoplasty clinical trials

View clinical trials related to Rhinoplasty.

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NCT ID: NCT06398275 Recruiting - Emergence Delirium Clinical Trials

Remimazolam for Emergence Delirium Prevention in Patients Undergoing Rhinoseptoplasty, FESS or Septoplasty

Start date: March 6, 2024
Phase: Phase 2
Study type: Interventional

The aim of this research is to confirm the effectiveness of remimazolam in preventing delirium during recovery from anesthesia in adult patients who have undergone one of the rhinological surgeries (septoplasty, rhinoseptoplasty or functional endoscopic sinus surgery). Patients aged 18-65, ASA classification I-II will be anesthetized with balanced anesthesia maintained with sevoflurane and will be randomized into two groups. The first group will receive remimazolam before anesthesia, while the second will receive normal saline solution. The main outcome of the study will be the presence/absence of delirium during anesthesia recovery, while the secondary outcome will be the postoperative pain level, the length of stay in the recovery room, the presence of unwanted events in the recovery room, and the presence of postoperative mood changes.

NCT ID: NCT06384469 Not yet recruiting - Rhinoplasty Clinical Trials

The Impact of Rhinoplasty Approach and Used Autologous Cartilage Grafts on the Nasal Skin-soft Tissue Envelope Metabolism

Start date: January 2, 2025
Phase:
Study type: Observational

This is a prospective observation cohort investigation. Patients, that is participants, undergoing primary functional rhinoplasty will be evaluated in terms of measuring capillary blood lactic acid concentration in the nasal skin-soft tissue envelope immediately after the procedure and 7 days after the procedure. The aim of our study is to test whether or not different rhinoplasty approaches and volume of the used autologous cartilage grafts impact the nasal skin-soft tissue metabolism.

NCT ID: NCT06370455 Recruiting - Rhinoplasty Clinical Trials

Comparison of Septal Advancement Flap and Columellar Strut Effect on Nasal Tip

Start date: January 23, 2024
Phase: N/A
Study type: Interventional

The aim of the study to compare and evaluate the effect of septal advancement flap in preserving and reshaping the nasal tip with columellar strut graft

NCT ID: NCT06157970 Completed - Pain, Postoperative Clinical Trials

Sphenopalatine Ganglion Block in Septorhinoplasty

Start date: June 7, 2023
Phase:
Study type: Observational

Septorhinoplasty is a widely performed surgery that aims to correct both functional and aesthetic problems of the nose. Despite its expected clinical benefits, septorhinoplasty surgery causes postoperative pain, which affects the patient's functional recovery and satisfaction. Opioids, Non-steroidal anti-inflammatory drugs (NSAII), acetaminophen and local anesthetics are used in peroperative pain management in septorhinoplasty. Sphenopalatine ganglion block (SPGB), which has been recently described and has different application areas, is a regional analgesia technique that has been investigated for this purpose. Although there are studies on postoperative pain in septorhinoplasty surgeries, there are not enough studies on its effects on intraoperative pain. This study may have positive effects on appropriate pain management, patient comfort and surgical outcomes as multimodal analgesia management in septorhinoplasty surgeries, and may make significant contributions to evidence-based practices.

NCT ID: NCT05964868 Enrolling by invitation - Pain Management Clinical Trials

Efficacy of Liposomal Bupivacaine Post Septorhinoplasty

Start date: February 5, 2024
Phase: Phase 3
Study type: Interventional

The objective of this study is to determine if there is a difference in post-operative pain after septorhinoplasty when long-acting liposomal bupivacaine is used for local anesthesia compared to other standard local anesthetic regimens.

NCT ID: NCT05695794 Recruiting - Rhinoplasty Clinical Trials

The Effect of Different Bed Head Heights on Patients After Rhinoplasty

Start date: December 8, 2022
Phase: N/A
Study type: Interventional

This study will be conducted to evaluate the effect of different bed head heights (thirty degrees and forty-five degrees) given to patients after rhinoplasty surgery on periorbital edema, periorbital ecchymosis, respiratory function and sleep quality.

NCT ID: NCT05601674 Completed - Emergence Agitation Clinical Trials

The Effect of Low Flow Anesthesia on Postoperative Emergence Agitation in Rhinoplasty

Start date: November 4, 2022
Phase: N/A
Study type: Interventional

Emergence agitation, defined as restlessness, disorientation, arousal, and/or inconsolable crying, is a common phenomenon seen in the early phase of recovery from general anesthesia; this may cause respiratory depression, nausea and vomiting, as well as an increase in blood pressure, heart rate and myocardial oxygen consumption. Although its pathogenesis remains unclear, ENT (ear, nose and throat) surgical procedures have been reported to have a higher incidence of agitation in both adults and children. In recent years, low-flow inhalation anesthesia has been widely used in adult anesthesia practice. The aim of this study is to compare the effects of low flow anesthesia and normal flow anesthesia on emergence agitation.

NCT ID: NCT05572723 Completed - Dexmedetomidine Clinical Trials

Comparison of the Effects of Remifentanil and Dexmedetomidine Administered Under General Anesthesia in Rhinoplasty

Start date: March 1, 2022
Phase: Phase 4
Study type: Interventional

The investigators compared the effects of remifentanil and dexmedetomidine administered under general anesthesia on hemodynamics, postoperative pain, recovery, postoperative nausea, vomiting, shivering, patient's and surgeon's satisfaction in patients undergoing elective rhinoplasty. A single-center, prospective, blinded, randomized controlled trial. After the approval of the hospital ethics committee (KA22/12), fifty volunteers aged 18-65 years who underwent rhinoplasty under elective conditions accepted the study in the American Society of Anesthesiologists (ASA) I-III class. The patients were randomly divided into the remifentanil group (group R) and the dexmedetomidine group (group D). Group R (n=25) was initially to receive remifentanil 0.01-0.2 g/kg/min without intraoperative loading. Group D (n=25) dexmedetomidine, was initiated with a bolus of 1 mg/kg and received 0.2-0.7 g/kg per hour as an infusion during surgery.

NCT ID: NCT05566808 Completed - Rhinoplasty Clinical Trials

Use of Allograft Cartilage in Cosmetic and Reconstructive Rhinoplasty

Start date: March 1, 2017
Phase: N/A
Study type: Interventional

This is a single-center, blinded, controlled trial, conducted in healthy adult subjects undergoing a reconstructive or cosmetic rhinoplasty involving the use of cartilaginous graft (either non-irradiated cartilage sheet allograft compared to autologous harvest and grafting of costal cartilage).

NCT ID: NCT05326139 Completed - Edema Clinical Trials

Topical Tranexamic Acid Application in Rhinoplasty

Start date: June 7, 2021
Phase: Phase 4
Study type: Interventional

The aim of this study is to examine the effectiveness of topical Tranexamic acid application in overcoming periorbital ecchymosis and edema after rhinoplasty, which are common and do not have a standard treatment.