Clinical Trials Logo
  1. Home
  2. Rheumatic Heart Disease
  3. NCT05668611

Train the Trainer Curriculum to Scale up AI Supported Echo for RHD Screening in a Public Health System — ADD-RHD 2B  

Rheumatic Heart Disease Clinical Trial

Official title:
Design and Evaluation of a Train the Trainer Curriculum to Scale Up Automated Intelligence Supported Echocardiography for Rheumatic Heart Disease Screening in a Public Health Care System

Clinical Trial Summary

The first primary objective of this study is to determine the diagnostic performance (sensitivity and specificity) of primary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation by expert trainers to accurately identify patients who are screen positive and screen negative for rheumatic heart disease. The second primary objective is to determine the diagnostic performance (sensitivity and specificity) of secondary MOH nurses who have completed certification in focused echocardiography acquisition and interpretation by MOH nurse trainers to accurately identify patients who are screen positive and screen negative for rheumatic heart disease.

Clinical Trial Description

Objective 1: 4 ultrasound naïve nurses (Primary) employed at the HCIII/IVs participating in ADD-RHD Part 1 (SOMREC REF 2021-61) in Lira, will be trained and certified by experts in echocardiography for RHD on focused RHD echocardiographic screening examination and interpretation using a novel AI guided software. Focused RHD screening echocardiograms by the 4 nurses will be integrated into routine clinical practice at their assigned HCIII/IVs for 1 month. Screen positive patients will be referred to LRRH for confirmatory echocardiogram using a Standard echocardiographic machine under the National RHD registry (SOMREC REF 2014-137). All echocardiograms will be uploaded to a secure cloud-based server and over-read by a cardiologist with in one - two (1 - 2) weeks to ensure patient safety and to determine trainee performance. Diagnostic accuracy, sensitivity, specificity, positive and negative predictive values will be calculated. 4 MOH trainees will use pre-recorded PowerPoint presentations to conduct hands-on training for phase 2 (secondary) nurses. Objective 2: Similar to Phase 1 with just a few exceptions. 12 MOH nurses will be trained and certified by MOH nurse trainers from phase 1 to acquire and interpret RHD focused screening echocardiograms using a novel AI guided software. Screening will be integrated into routine care for 2 months and diagnostic performance assessed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05668611
Study type Interventional
Source Children's Hospital Medical Center, Cincinnati
Contact
Status Completed
Phase N/A
Start date January 3, 2023
Completion date December 20, 2023
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT05991219 - Screening and Secondary Prevention Rheumatic Heart Disease Study
Completed NCT02661763 - Rheumatic Heart Disease Study in Lusaka N/A
Completed NCT02188862 - Genetic Susceptibility to Rheumatic Heart Disease in the Pacific Region N/A
Completed NCT01178710 - Effect of Simvastatin on Cardiac Function N/A
Recruiting NCT05693545 - GOALIE: Intramuscular vs. Enteral Penicillin Prophylaxis to Prevent Progression of Latent RHD Trial Phase 2
Completed NCT06150274 - Comparison of Wire Assisted Percutaneous Balloon Mitral Valvulotomy With Standard Inoue Balloon Valvulotomy N/A
Terminated NCT03926156 - RIvoraxaban in Mitral Stenosis Phase 3
Recruiting NCT05783375 - Accelerating Delivery of rheUmatic Heart Disease Preventive iNterventions in Northern Uganda N/A
Completed NCT02474108 - Surgical Prevention of Atrial Fibrillation in Patients With Rheumatic Mitral Valve Lesion and Left Atrium Enlargement N/A
Recruiting NCT04556188 - The Clinical Influence of Developing a Sustainable Cardiac Surgery Service to Reduce the Burden of Rheumatic Heart Disease in Sub-Saharan Africa
Recruiting NCT03991910 - The Effect of Ramipril in Suppressing ST2 Expression in Rheumatic Mitral Stenosis Patients Phase 3
Active, not recruiting NCT03346525 - Determining the Impact of Penicillin in Latent RHD: The GOAL Trial Phase 2
Recruiting NCT05504928 - Effectiveness of a School-centered Prevention Program on Prevalence of Latent Rheumatic Heart Disease N/A
Not yet recruiting NCT03549052 - Right Ventricular Echo Assessment in Mitral Valve Replacement
Recruiting NCT05487469 - Thymosin α1 Use in Rheumatic Heart Disease Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass N/A
Completed NCT05276999 - Rheumatic Heart Disease Community Streptococcal Treatment Program "RESET" N/A
Active, not recruiting NCT05211024 - A Long-term Follow up Study for Patients Who Participated in the GOAL Trial (GOAL-Post)
Withdrawn NCT02832531 - INVestIgation of rheumatiC AF Treatment Using Vitamin K Antagonists, Rivaroxaban or Aspirin Studies, Superiority Phase 3
Completed NCT01794884 - Validity Study of Glutamine to Improve Cardiac Function in Cardiac Surgery Phase 2
Completed NCT00264524 - DNA Typing of HLA-DR/DQ Alleles in Taiwan Chinese With Rheumatic Heart Disease N/A