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Retrognathia clinical trials

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NCT ID: NCT06297109 Recruiting - Clinical trials for Malocclusion, Angle Class II

Maxillary Patient Specific Implants in Bimaxillary Orthognathic Surgery

Start date: September 12, 2023
Phase: N/A
Study type: Interventional

Orthognathic surgery is a type of jaw surgery where a surgeon cuts the bones of the upper and lower jaw and places them better. There are two ways they can put the bones in the correct place and keep them in place after the surgery. One way, called the "conventional method", is to use a 3D-printed guide called a splint to set the bones in the right place and then screw the bones together using metal plates that the surgeon bends into shape to fit during the surgery. Another way is to use a patient-specific implants (PSI) that has been 3D-printed in titanium beforehand that because of its unique shape both places and keeps all the bones in the correct place after they are screwed in. Both ways of doing it are golden standards, meaning they are already approved. Measuring the accuracy of the surgery is done by comparing the positions of the bones after the surgery with the intended positions of those bones, according to the surgical plan. The closer the achieved position of each bone is to the intended position, the more accurate the result. Measuring the stability of the surgery is done by comparing the positions of the bones after the surgery with the positions of the bones two years later. The less the position is changed, the more stable the result. The goal of this clinical trial is to see how accurate and stable PSIs are in orthognathic surgery when the maxilla is split in 3 pieces, and to compare them with the conventional method in patients with overjet or overbite. The main questions it aims to answer are: - Does using PSIs provide accurate movements of the maxilla pieces? - Does using PSIs provide more accurate movements of the maxilla pieces than the conventional method? - Does using PSIs provide stable movements of the maxilla pieces after 2 years? - Does using PSIs provide more stable movements of the maxilla pieces than the conventional method? Participants will get orthognathic surgery as part of their normal orthodontic treatment. Investigators will compare the PSI and conventional groups to see if the PSIs are more accurate than the conventional method.

NCT ID: NCT05913076 Completed - Clinical trials for Maxillary Retrognathism

Class III Malocclusion and ALT-RAMEC

Start date: January 13, 2012
Phase: N/A
Study type: Interventional

Diverse viewpoints exist regarding the correlation between the conventional rapid maxillary expansion (RME) and facemask approach and the alternative RME and facemask hybrid technique (Alt-RAMEC) in terms of the degree of maxillary protraction. The findings of the study may offer a novel approach to protocol selection based on the anomaly's degree of severity. The objective of this investigation is to assess and contrast the skeletal and dentoalveolar outcomes of three distinct Alt-RAMEC techniques.

NCT ID: NCT05536596 Not yet recruiting - Clinical trials for Orthognathic Surgery

Pharmacological Treatment on the Recovery of Neurosensory Disturbance After Bilateral Sagittal Split Osteotomy

Start date: September 30, 2022
Phase: Phase 2/Phase 3
Study type: Interventional

The bilateral sagittal split osteotomy (BSSO) of the mandible is one of the most used surgical techniques to achieve a harmonious jaw relation in the context of orthognathic surgery. Nevertheless, one of its main complications is neurosensory damage to the inferior alveolar nerve, which can cause severe impact in the quality of life on patients who suffer from it permanently. The purpose of this randomized clinical trial is to provide rigorous scientific evidence of the pharmacological effect of 1) Melatonin, 2) combination uridine triphosphate (UTP), cytidine monophosphate (CMP), and hydroxycobalamin (UTP/CMP/hydroxycobalamin) and 3) hydroxycobalamin regarding neurosensory disturbances incidence and persistence after BSSO.

NCT ID: NCT05446714 Active, not recruiting - Clinical trials for Nasal Airway Obstruction

Evaluation of the Effect of Three Types of Rapid Maxillary Expanders (Conventional, Hybrid and MSE)

Start date: April 30, 2022
Phase: N/A
Study type: Interventional

Aim of the study: To compare radiographically the morphometric changes in the nasal airway after using three types of rapid maxillary expansion (RME) conventional hyrax (CH), hybrid hyrax (HH) and maxillary skeletal expander (MSE) using cone beam computed tomography (CBCT).

NCT ID: NCT05205616 Completed - Fracture Clinical Trials

Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation

Start date: July 20, 2021
Phase: N/A
Study type: Interventional

The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw. Patients included in the study are ages 15-45 scheduled to undergo BSSO surgery at the University of California, San Francisco. One side of the patient's mandible will be instrumented with either the Stryker Sonopet ultrasonic saw or traditional reciprocating saw, while the other side will receive the remaining intervention (determined via randomization on the day of surgery). Patient paresthesias will then be analyzed on each side for 3 months postoperatively (at postoperative days: 1, 7, 14, 28, and 84). Sensory examinations will be carried out by blinded examiners using von Frey hairs and two point discrimination testing. Patients will also subjectively rate their sensation on each side. The results will then be analyzed to determine if patient paresthesias, including the severity and duration, differed depending on which instrument was used, the ultrasonic or reciprocating saw.

NCT ID: NCT05151042 Recruiting - Clinical trials for Congenital Abnormalities

Digital Occlusal Wafer Versus Waferless Distal Segment Repositioning for BSSO in Skeletal Mandibular Deformities

Start date: November 15, 2021
Phase: N/A
Study type: Interventional

Research studies continues to attempt testing modifications to refine the treatment protocols through computer assisted design or computer-generated surgical Wafer splints, have greatly revolutionized the incorporation of digital imaging and 3D design in Orthognathic surgery. Integrating computer guided technology in orthognathic surgery aims to to simplify workup and reduce surgical errors, eliminate occlusal discrepancy, increase the realignment accuracy of the distal segments according to the preoperative plan. Implementing a waferless technique raised the question of efficiency versus the use of occlusal wafers and whether it has a significant measurable effect on the surgical outcome and objectives. Rationale for conducting this study is to assess the difference between the effect of computer guided waferless technique and computer guided technique with occlusal wafer on accuracy of postoperative occlusion and condylar position. .

NCT ID: NCT05089396 Recruiting - Clinical trials for Maxillary Deficiency

Effects of Conventional Versus Skeletally Anchored Facemask in Treatment of the Prepubertal Skeletal Class III Patients

Start date: November 22, 2021
Phase: N/A
Study type: Interventional

The aim of this study will be directed to the assessment of dentoskeletal effects concomitant with skeletally anchored maxillary protraction in orthodontic skeletal Class III patients.

NCT ID: NCT04619446 Completed - Clinical trials for Class II Division 1 Malocclusion

Dentoskeletal Changes Produced by Growth Modification Appliances in Treatment of Skeletal Class II Malocclusion

Start date: September 12, 2020
Phase:
Study type: Observational

To compare dentoskeletal changes in patients with skeletal class II malocclusion induced due to treatment with orthodontic appliances; removable twin block appliance and fixed AdvanSync2 appliance in two different age group patients.

NCT ID: NCT04562545 Not yet recruiting - Clinical trials for Mandibular Hypoplasia

Twin Block Appliance in Incremental Versus Maximum Bite Advancement in Skeletal Class II

Start date: September 15, 2020
Phase: N/A
Study type: Interventional

The aim of this study is to compare to different protocols to treat Class II malocclusion in growing subjects using the twin block appliance

NCT ID: NCT04283708 Not yet recruiting - Receding Chin Clinical Trials

Esthetic Outcome of Isolated Advancement Genioplasty With and Without Submental Liposuction in Treatment of Skeletal Chin Deficiency

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

This study is to measure the eshetic outcome of of isolated advancement genioplasty with and without submental liposuction in treatment of skeletal chin deficiency in double chin patients