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Retinitis Pigmentosa clinical trials

View clinical trials related to Retinitis Pigmentosa.

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NCT ID: NCT04252534 Completed - Clinical trials for Retinitis Pigmentosa

Management of Retinitis Pigmentosa Via Electromagnetic Stimulation and Platelet Rich Plasma

rEMS
Start date: January 1, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to investigate whether natural progression rate can be slowed down with subtenon PRP or PRP application combined with rEMS in retinitis pigmentosa cases.

NCT ID: NCT04238858 Completed - Clinical trials for Retinitis Pigmentosa

Effects of Subtenon-injected Autologous Platelet-rich Plasma on Visual Functions in Eyes With Retinitis Pigmentosa

PRP
Start date: September 1, 2016
Phase: N/A
Study type: Interventional

Purpose One of the main reasons for apoptosis and dormant cell phases in degenerative retinal diseases such as retinitis pigmentosa (RP) is growth factor withdrawal in the cellular microenvironment. Growth factors and neurotrophins can significantly slow down retinal degeneration and cell death in animal models. One possible source of autologous growth factors is platelet-richplasma.The purpose of this study was to determine if subtenon injections of autologous platelet-rich plasma (aPRP) can have beneficial effects on visual function in RP patients by reactivating dormant photoreceptors.

NCT ID: NCT04234438 Completed - Clinical trials for Retinitis Pigmentosa

Management of Cystoid Macular Edema Secondary to Retinitis Pigmentosa Via Subliminal Micropulse Yellow Laser

SL-MPL
Start date: January 1, 2018
Phase: N/A
Study type: Interventional

Purpose: To investigate the effects of subliminal micropulse yellow laser application on central macular thickness and best corrected visual acuity in cystoid macular edema secondary to retinitis pigmentosa patients.

NCT ID: NCT04224207 Completed - Clinical trials for Retinitis Pigmentosa

Management of Retinitis Pigmentosa by Mesenchymal Stem Cells by Wharton's Jelly Derived Mesenchymal Stem Cells

WJ-MSC
Start date: April 1, 2019
Phase: Phase 3
Study type: Interventional

The aim of this study is to determine if umbilical cord Wharton's jelly derived mesenchymal stem cells implanted in sub-tenon space have beneficial effects on visual functions in retinitis pigmentosa patients by reactivating the degenerated photoreceptors in dormant phase.

NCT ID: NCT04141891 Completed - Stroke Clinical Trials

Advancing Understanding of Transportation Options

AUTO
Start date: December 12, 2019
Phase: N/A
Study type: Interventional

This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers. This multi-site trial will (1) test the driving decision aid (DDA) in improving decision making and quality (knowledge, decision conflict, values concordance and behavior intent); and (2) determine its effects on specific subpopulations of older drivers (stratified for cognitive function, decisional capacity, and attitudinally readiness for a mobility transition). The overarching hypotheses are that the DDA will help older adults make high-quality decisions, which will mitigate the negative psychosocial impacts of driving reduction, and that optimal DDA use will target certain populations and settings.

NCT ID: NCT04068207 Completed - Clinical trials for Retinitis Pigmentosa

Minocycline Treatment in Retinitis Pigmentosa

Start date: August 25, 2019
Phase: Phase 2
Study type: Interventional

The aim of this study is to evaluate the efficacy and safety of oral minocycline (100mg/d), administered for 6 months, for the treatment of patients with retinitis pigments(RP).

NCT ID: NCT04008771 Completed - Clinical trials for Retinitis Pigmentosa

Intravitreal Injection of SeeQ CdSe 655 Alt Nanoparticles for Patients With Degenerative Retinal Diseases

Start date: January 6, 2014
Phase: N/A
Study type: Interventional

This study was a prospective, open label feasibility study conducted at a single clinical site (APEC, Mexico City) to evaluate the safety and preliminary effectiveness of the SeeQ device, with each patient's serving as his/her own contralateral control.

NCT ID: NCT03901391 Completed - Clinical trials for Retinitis Pigmentosa

Prospective Open Clinical and Genetic Study of Patients With Retinitis Pigmentosa

RU-RP
Start date: March 26, 2019
Phase:
Study type: Observational

This study is aimed to characterize Russian population of Retinitis Pigmentosa

NCT ID: NCT03780257 Completed - Clinical trials for Retinitis Pigmentosa

Study to Evaluate Safety and Tolerability of QR-421a in Subjects With RP Due to Mutations in Exon 13 of the USH2A Gene

Stellar
Start date: March 6, 2019
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of QR-421a administered via intravitreal injection (IVT) in subjects with Retinitis Pigmentosa (RP) due to mutations in exon 13 of the USH2A gene.

NCT ID: NCT03626207 Completed - Clinical trials for Retinitis Pigmentosa

Development of Visual Function Evaluation Method (2)

Start date: October 4, 2018
Phase:
Study type: Observational

The objective of this study is to develop the comprehensive visual function evaluation method in severe visually impaired patient.