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Resynchronization Therapy clinical trials

View clinical trials related to Resynchronization Therapy.

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NCT ID: NCT05187611 Active, not recruiting - Clinical trials for Conduction System Pacing

Conduction System Pacing vs Biventricular Resynchronization Therapy in Systolic Dysfunction and Wide QRS: CONSYST-CRT.

CONSYST-CRT
Start date: January 17, 2022
Phase: N/A
Study type: Interventional

Conduction system pacing vs biventricular resynchronization therapy in systolic dysfunction and wide QRS (CONSYST-CRT randomized clinical trial) is a non-inferiority trial that aims to study the composite endpoint consisting of all-cause mortality, cardiac transplant, heart failure hospitalizations, and left ventricular ejection fraction (LVEF) improvement <5 points.

NCT ID: NCT05155865 Active, not recruiting - Heart Failure Clinical Trials

Conduction System Pacing Versus Biventricular Pacing for Cardiac resYNChronization

CSP-SYNC
Start date: January 10, 2022
Phase: N/A
Study type: Interventional

Cardiac resynchronization therapy (CRT) with biventricular pacing (BiV) is the cornerstone treatment for heart failure patients with ventricular dyssynchrony. Recently, a new concept, conduction system pacing (CSP) with permanent pacing, including His bundle pacing and left bundle branch pacing, has been proposed as a potential alternative to conventional BiV-CRT. The prospective, randomized trial will compare echocardiographic, electrocardiographic, and clinical effects of CSP versus conventional BiV pacing in heart failure patients with reduced ejection fraction (LVEF ≤ 35%), sinus rhythm, and left bundle branch block. Patients will be randomized to either CSP or biventricular pacing study group and followed up for at least 6 months. The study will explore whether CSP is non-inferior to BiV pacing in echocardiographic, electrocardiographic, and clinical outcomes.

NCT ID: NCT04054895 Completed - Clinical trials for Resynchronization Therapy

LEft VEntricuLar Activation Time Shortening With Physiological Pacing vs Biventricular Resynchronization Therapy

LEVEL-AT
Start date: September 1, 2019
Phase: N/A
Study type: Interventional

The LEVEL-AT Trial (LEft VEntricuLar Activation Time Shortening with Physiological Pacing vs Biventricular Resynchronization therapy: a randomized study) is a non-inferiority study that aims to determine if physiological pacing could decrease the left ventricular activation time compared with biventricular therapy.

NCT ID: NCT01996397 Completed - Heart Failure Clinical Trials

Acute Feedback on Left ventrIcular Lead Implantation Location for Cardiac Resynchronization Therapy

CCI impact
Start date: May 2013
Phase: N/A
Study type: Interventional

Exploratory, prospective, interventional, non-randomized single-center research study to compare metrics derived from 2 or 3-D reconstructions of lead movement, bioimpedance and VCG to augmentation of left ventricular contractility (LV dP/dt max) at different pacing configurations in patients undergoing a CRT-implant. Pacing sites and contractility data will be compared to pre operative cardiac ultrasound and MRI metrics.