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Clinical Trial Summary

The pathophysiology of SARS-COV-2 related respiratory disease is still poorly understood, especially in its most severe form called acute respiratory distress syndrome (ARDS). In this case, very few studies have investigated changes in gas exchange during COVID-19 progression in spontaneously breathing patients. The investigators purpose in this study to explore the pathophysiology of gas exchange and time course changes in spontaneously breathing patients with acute respiratory failure due to COVID-19. Moreover, our aim is to identify early markers associated with worsening respiratory failure and requiring endotracheal intubation.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05392062
Study type Interventional
Source CHU de Reims
Contact Antoine GOURY
Phone 03 10 73 68 85
Email agoury@chu-reims.fr
Status Recruiting
Phase N/A
Start date June 9, 2021
Completion date September 9, 2022

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