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Respiratory Function Impaired clinical trials

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NCT ID: NCT06288984 Not yet recruiting - Brain Injuries Clinical Trials

Effects of rTMS on Respiratory Function and Gut Microbiota in Patients With Brain Injury

Start date: March 1, 2024
Phase: N/A
Study type: Interventional

Impaired respiratory function may occur after brain injury, and will progress to restricted respiratory dysfunction without early intervention. At present, there is a lack of effective treatment options for respiratory dysfunction. Repetitive Transcranial Magnetic Stimulation(rTMS) is a non-invasive, painless and non-invasive neuroregulatory technique. In healthy people, rTMS applied to the respiratory motor cortex induces a contralateral respiratory muscle response. However, whether rTMS can improve respiratory function in patients with brain injury remains unclear. gut microbiota can affect muscle function and mass, and animal experiments have shown that probiotics can increase skeletal muscle mass and grip strength in mice. On the other hand, studies have found that rTMS can improve the nutritional status of patients with vegetative state by regulating the structure of gut microbiota. However, it remains unclear whether rTMS can improve respiratory muscle function in patients with brain injury by regulating gut microbiota. Therefore, the investigators intend to apply rTMS to the respiratory motor cortex to observe whether rTMS can improve respiratory function and reduce the incidence of pneumonia in patients with brain injury, and to observe the role of gut microbiota in this process.

NCT ID: NCT06181123 Completed - Physical Inactivity Clinical Trials

Cardiopulmonary Assesments in Mood Disorders

Start date: May 1, 2023
Phase:
Study type: Observational

The importance of cardiorespiratory impact in mental diseases is generally emphasized in studies, but it is noteworthy that cardiorespiratory affects in mood disorders have not been sufficiently investigated. This study aims to compare individuals with mood disorders and healthy people in terms of exercise capacity, functionality, respiratory muscle strength, respiratory functions, dyspnea and physical activity level.

NCT ID: NCT06130800 Recruiting - Sarcopenia Clinical Trials

Respiratory Sarcopenia in Institutionalized Older Adults in the Region of Murcia

Start date: May 1, 2023
Phase:
Study type: Observational [Patient Registry]

Objectives: The objectives of this study are to describe the prevalence of respiratory sarcopenia in institutionalized older adults. Methodology: A sample of approximately 120 older adults from 5 residences located in Murcia capital will participate in the study. A prospective observational study will be carried out, with one year of follow-up, with patients who have been diagnosed with respiratory sarcopenia. Sociodemographic and clinical variables, physical function (palm grip, 5STS, 4MGS), respiratory force variables (MIP and PEF) and diaphragmatic ultrasound (thickness, shortening fraction and diaphragmatic excursion) will be measured. Descriptive statistics, univariate and multivariate logistic regression models, Cox proportional hazards model and KaplanMeier curves will be used to analyze the data from the longitudinal study.

NCT ID: NCT05835128 Active, not recruiting - COVID-19 Pneumonia Clinical Trials

Assessment of Long-term Sequelae of Coronavirus Disease 2019 (COVID-19) Pneumonia With Chest CT and Pulmonary Function Tests

Start date: March 1, 2020
Phase:
Study type: Observational

The goal of this prospective multicentric study is to evaluate the presence of long-term pulmonary sequelae in patients who had required hospitalization for treating COVID-19 pneumonia, trough chest CT and pulmonary function tests (PFT). Secondly we would like to evaluate the possible correlation between the chest CT findings and pulmonary function tests pre-existing co-morbidities and type of therapy used during hospitalization.

NCT ID: NCT05756894 Recruiting - Clinical trials for Spinal Cord Injuries

Neurostimulation for Respiratory Function After Spinal Cord Injury

Start date: February 28, 2023
Phase: N/A
Study type: Interventional

The purpose of this research study is to learn more about the connections between the brain, nerves, and diaphragm after experiencing a cervical spinal cord injury (SCI).The main question it aims to answer is: Changes in respiratory function and recovery using stimulation and respiratory exercise training in spinal cord-injured individuals. Participants will complete a maximum of 55 study visits. They will be asked to complete about 40 treatment sessions which include multiple stimulation sessions over the scalp and neck, followed by about 60 minutes of respiratory training. Assessment sessions will be completed prior at baseline, after 20 sessions and after 40 sessions of study treatment.

NCT ID: NCT05603507 Completed - Burns Clinical Trials

Inspiratory Muscle Training in Children With Chest Burn

chestburn
Start date: September 10, 2021
Phase: N/A
Study type: Interventional

8 weeks of inspiratory muscle training combined with a pulmonary rehabilitation program increases respiratory muscle strength, pulmonary function, functional capacity, and quality of life in chest burned children.

NCT ID: NCT05547932 Completed - Breast Cancer Clinical Trials

The Effect of Rhomboid Intercostal Block and Serratus Anterior Plane Block on Postoperative Respiratory Functions

RIBSAB
Start date: September 21, 2022
Phase: N/A
Study type: Interventional

Rhomboid intercostal block is used to block lateral cutaneous branches of intercostal nerves between T3 and T9 dermatomes. Serratus anterior plane block is used to block lateral cutaneous branches of intercostal nerves between T2 and T6, in addition, it is also known to block thoracodorsal nerve and long thoracic nerve. Both of the blocks are usually performed for postoperative analgesia following breast surgery. The primary hypothesis of the study is that FEV1 value of the patients who will receive modified radical mastectomy (MRM) and rhomboid intercostal plane (RIP) block combined with serratus anterior plane (SAP) will be higher than FEV1 value of the patients in the no-block group. The secondary hypothesis is that RIP+SAP blocks will provide reduction in the pain scores and opioid consumption in the postoperative first 24 hours.

NCT ID: NCT05532228 Completed - Infections Clinical Trials

Evaluation of the Functional Impact of Adenotonsilectomy

Start date: August 20, 2020
Phase:
Study type: Observational

Spirometric assessment of respiratory function before and after adenotonsillectomy surgery

NCT ID: NCT05021068 Completed - COPD Clinical Trials

Spinal Structure and Mobility in Chronic Obstructive Pulmonary Disease

Start date: March 1, 2018
Phase:
Study type: Observational [Patient Registry]

In recent studies with musculoskeletal system disorders in chronic respiratory patients, it has been reported that postural control is affected in COPD patients. The aim of this study to investigate relationship between spinal structure and mobility an severity of dyspnea in patients with COPD.

NCT ID: NCT04975542 Completed - Clinical trials for Respiratory Function Impaired

Efficacy of Osteopathic Manipulation on Breathing Mechanics in a Healthy Population: A Randomized Controlled Study

Start date: September 23, 2019
Phase: N/A
Study type: Interventional

This study focused on improving breathing mechanics by using various osteopathic manipulative therapy (OMT) techniques. The investigators randomly assigned participants to a control group who received sham treatment and a treatment group who received OMT. The investigators measured variable pre- and post- treatment on both groups. The investigators observed an improvement in breathing mechanics in the treatment group.