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NCT04654273 Clinical Trial

EX-PO Trial : Evaluation of the Occlusion Pressure (PO.1) in Extubation Failure

Respiratory Failure Clinical Trial

Official title:
EX-PO Trial : Evaluation of the Occlusion Pressure (PO.1) in Extubation Failure

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04654273
Other study ID # EX-PO
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date November 30, 2020
Est. completion date January 31, 2022

Study information
Verified date January 2021
Source Poitiers University Hospital
Contact Damien MARIE, Dr
Phone 05.49.44.15.65
Email damien.marie@chu-poitiers.fr
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Measuring bedside occlusion pressure in neurosurgical or surgical critically ill patients could tell us about the patient's respiratory drive, and therefore, tell us whether or not extubation will be successful.

Recruitment information / eligibility
Status Recruiting
Enrollment 152
Est. completion date January 31, 2022
Est. primary completion date December 31, 2021
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Age = 18 years old, - Hospitalized in surgical or neurosurgical intensive care units - Patients under mechanical ventilation for more than 48 hours, - Meeting the criteria for severability (spontaneous ventilation test), - Free subject, without tutorship or curatorship or subordination, - Patients benefiting from a Social Security scheme or benefiting through the intermediary of a third party, - No objection given by the patient and / or relative after clear and fair information about the study. Exclusion Criteria: - Tracheostomized patients, - Persons benefiting from enhanced protection, namely minors, persons deprived of their liberty by a judicial or administrative decision, persons staying in a health or social establishment, adults under legal protection, - Pregnant and / or lactating women.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
France CHU POitiers Poitiers

Sponsors (1)
Lead Sponsor Collaborator
Poitiers University Hospital

Country where clinical trial is conducted

France, 

Outcome
Type Measure Description Time frame Safety issue
Primary Number of re-intubations after extubation 7 days
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