Postoperative Complications Clinical Trial
Official title:
Endocan Predictive Value in Postcardiac Surgery Acute Respiratory Failure. The ENDOLUNG Study
According to literature data, Endocan can detect the onset of respiratory failure. The investigators aim to prove its value also for cardiac surgery patients.
Endocan is an endothelium derived soluble dermatan sulfate proteoglycan. Literature data
shows that alterate levels of its blood concentration correlate with the onset of pulmonary
failure in patients with major trauma and septic shock.
In cardiac surgery respiratory failure and infections are threatening complications leading
to mortality rates up to 80%. A rapid diagnosis and treatment of this pathology is crucial
to improve the clinical outcome.
Unfortunately specific data for the efficacy of Endocan predictive value in cardiac surgery
patients are not available.
The investigators aim to determinate if Endocan can be a helpful tool to identify patients
developing acute respiratory failure after cardiac surgery and anticipate specific treatment
in order to improve survival.
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Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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