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Respiratory Aspiration clinical trials

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NCT ID: NCT05632874 Not yet recruiting - Bone Marrow Cancer Clinical Trials

The Effect of Relaxing Breathing Exercise Applied to Patients Before Bone Marrow Biopsy on Vital Signs, Pain and Anxiety Levels

Start date: November 2022
Phase: N/A
Study type: Interventional

There is no study in the literature that determined the effect of relaxing breathing exercise applied to patients before the BMB procedure on vital signs, pain and anxiety levels. The aim of this study is to determine the effect of relaxing breathing exercise applied to patients before bone marrow biopsy on vital signs, pain and anxiety levels. hypotheses H1. Relaxing breathing exercise applied to the patients before the bone marrow biopsy procedure reduces the anxiety level of the patients compared to the control group. H2. Relaxing breathing exercise applied to the patients before the bone marrow biopsy procedure reduces the pain level of the patients compared to the control group. H3. Relaxing breathing exercise applied to the patients before the bone marrow biopsy procedure is effective on the respiratory rate of the patients compared to the control group. H4. Relaxing breathing exercise applied to the patients before the bone marrow biopsy procedure is effective on the pulse rate of the patients compared to the control group. H5. Relaxing breathing exercise applied to the patients before the bone marrow biopsy procedure is effective on the blood pressure of the patients compared to the control group.

NCT ID: NCT05585086 Not yet recruiting - Inhalation; Oil Clinical Trials

Effect of Peppermint Oil Inhalation on Postoperative Nausea, Vomiting and Comfort

Start date: December 20, 2022
Phase: N/A
Study type: Interventional

Nausea and vomitting related to drugs and anesthetic methods are among the important postoperative problems. Nausea and vomitting causing illlness feeling of patient are frequent after surgical interventions, cause increased dissatisfaction of the patient and prolonged discharge period. In this study it was aimed to evaluate the effect of peppermint oil inhalation on postoperative nausea and vomitting. Purpose and Type of Research The randomized controlled study will be performed on patients undergoing laparoscopic cholecystectomy, which is the most commonly performed surgical procedure, in a general surgery clinic of a training and research hospital.

NCT ID: NCT05571982 Not yet recruiting - Clinical trials for Adult Patients 20 Years of Age or Older Who Are Planning to Undergo Surgery Under General Anesthesia

Comparison of the Efficacy of Tidal Volume Breathing and Vital Capacity Breathing During High-flow Nasal Oxygen

Start date: October 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the preoxygenation efficacy of tidal volume breathing and vital capacity breathing.

NCT ID: NCT05542069 Not yet recruiting - Clinical trials for Physical Therapy Modalities, Respiratory Muscles, Maximal Respiratory Pressures, Breathing Exercise

Measurement of the Diaphragm Loading During the Training With a IMT Device

Start date: November 1, 2022
Phase:
Study type: Observational

It is well known that the the training with the IMT device increases the Maximal Inspiratory Pressure. Nonetheless, there are doubts about which muscles are involved during this training. The aim of this study is to determine the diaphragm loading of healthy subjects during the training with a IMT device from a low . Therefore, each subject will be monitored using esophageal and gastric manometry.

NCT ID: NCT05536635 Not yet recruiting - Migraine Headaches Clinical Trials

Effect of Breathing Techniques on Migraine Attacks and Severity

Start date: November 1, 2022
Phase: N/A
Study type: Interventional

Background: Migraine is a very common neurobiological disorder caused by increased excitability of the Central Nervous System. It is among the causes of the highest morbidity worldwide. Migraine has considerable economic and social impact ; affects the quality of life of patients and disrupts work life, social activities and family life. To decrease the frequency and severity of migraine attacks may be the first goal than treating the attacks. The study was designed as a Parallel Group, Add on, Randomized Controlled Experiment in order to observe the effects of breathing techniques on migraine-like headaches, frequency and severity. Methods: Participants will be divided into 2 parallel arms, intervention and control (treatment as usual). Cluster randomization will be performed to prevent intergroup contamination. Breathing techniques will be taught to the intervention group by the researcher. Both groups will continue to use pharmacotherapy for migraine. Both groups will be evaluated with migraine disability level (MIDAS) at the beginning and end of the study. The primary output of the study is to evaluate the effect of breathing techniques on the frequency and severity of attacks in migraine-like headaches. The secondary output is to evaluate the effect of breathing techniques on the MIDAS level. Discussion: The results of the study will provide information about the effect of breathing techniques on migraine-like headaches. The results of this study will contribute to the literature, since migraine is among the chronic diseases and pharmacotherapy options are limited.

NCT ID: NCT05533931 Not yet recruiting - Chronic Bronchitis Clinical Trials

Resistive Breathing Versus Inspiratory Hold Technique in Patients With Chronic Bronchitis

Start date: September 2022
Phase: N/A
Study type: Interventional

The aim of the study is to determine the importance and impact of resistive breathing techniques versus inspiratory hold techniques in patients with chronic bronchitis and specially to find out if there are any changes seen in results measured via the incentive spirometer.

NCT ID: NCT05487573 Not yet recruiting - Extubation Failure Clinical Trials

Performance of the Variation in Arterial Lactatemia During a Spontaneous Breathing Trial (SBT) in the Prediction of Extubation Failure

PREDILACT
Start date: September 15, 2022
Phase:
Study type: Observational

Extubation failure (EF) is independently associated with excess mortality of critically ill patients. To avoid EF, critically ill patients being weaned from invasive mechanical ventilation (IMV) perform spontaneous breathing trial (SBT), which is the litmus test for determining the ability to breathe without a ventilator. Thus, the performance of the SBT during weaning from IMV to predict successful extubation is crucial. The investigators hypothesize that patients with EF increase arterial lactate concentration during SBT due to increased work of breathing and hypoxia. The aim of this study is to evaluate the performance of variation in arterial lactate concentration before and after SBT in predicting successful extubation in critically ill patients.

NCT ID: NCT05486273 Not yet recruiting - Clinical trials for Hematological Cancer

Evaluation of the Impact of Sports-inspired Onco-coaching on Health-related Quality's Life of the Patients in Cancer Remission After Allogeneic Transplantation of Hematopoietic Stem Cells

Start date: January 2, 2023
Phase: N/A
Study type: Interventional

To measure the impact of a coaching program on the patient's health-related quality of life 15 months post-transplant (M15/R12).

NCT ID: NCT05462834 Not yet recruiting - Glucose Intolerance Clinical Trials

Impact of Nocturnal Hypoxemia on Glucose in High Altitude Sleep Disordered Breathing

Start date: September 1, 2024
Phase: N/A
Study type: Interventional

Sleep disordered breathing is associated with impaired glucose tolerance and incident diabetes. Nocturnal hypoxemia is a potential stimulus of glucose intolerance. It is especially severe and highly prevalent in high altitude residents. Intervening on nocturnal hypoxemia may therefore improve glucose control and decrease the public health burden in high altitude populations. The objective of this study is to examine the impact of hypoxemia on glucose homeostasis in high altitude residents. The investigators will address this objective by examining the effect of supplemental oxygen on glucose in a randomized cross-over study.

NCT ID: NCT05415241 Not yet recruiting - Clinical trials for Close Contact Transmission

Exploratory Study of Aerosol Inhalation of FB2001 for Post-exposure Prophylaxis of COVID-19 Close Contacts

Start date: June 9, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This is a single-arm, open-label, dose ramp-up exploratory clinical trial to evaluate the efficacy, safety and tolerance of aerosol inhalation of FB2001 as post-exposure prophylaxis among close contacts of COVID-19 patients. This study will enroll 20 to 60 close contacts of COVID-19 patients aging 18 to 65 years. After signing the informed consent form, the qualified subjects will be given FB2001 once or twice daily.