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NCT05725122 Clinical Trial

Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy

Renal Stone Clinical Trial

Official title:
Stone Clearance in Patients With Upper Ureteric Stones Using Extracorporeal Shock Wave Lithotripsy Compared With Extracorporeal Shock Wave Lithotripsy Combined With Tamsulosin Therapy

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05725122
Other study ID # S23
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date February 1, 2018
Est. completion date December 31, 2021

Study information
Verified date February 2023
Source Services Hospital, Lahore
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

Extracorporeal shock wave lithotripsy (ESWL) is the least invasive and effective treatment for upper ureteric stones with a stone clearance rate of 60-90%. Tamsulosin is an alpha-blocker widely used in urological practice to relax smooth muscle of the prostate and bladder neck. Its role as part of medical expulsion therapy for the treatment of patients with kidney and ureteric stones has proved to be of considerable success. However, its role in clearing upper ureteric stones as an adjunct to ESWL is controversial. Therefore, this study will be conducted to evaluate its role in stone clearance along with extracorporeal shock wave lithotripsy in patients with upper ureteric stones

Recruitment information / eligibility
Status Completed
Enrollment 82
Est. completion date December 31, 2021
Est. primary completion date December 31, 2021
Accepts healthy volunteers No
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria: - single upper ureteric stone - size ranging from 6-15 mm - stones history less than 6 months Exclusion Criteria: - Patients with urinary tract infection - multiple ureteric stones, - presence of a ureteric stricture distal to the stone, - previous unsuccessful ESWL, - concomitant use of calcium channel blockers or alpha-adrenergic antagonists - patients with abnormal coagulation profile

Study Design

Related Conditions & MeSH terms

Intervention

Procedure:
• Extracorporeal shock wave lithotripsy
Extracorporeal shock wave lithotripsy will given to the patients
• Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy.
Extracorporeal Shock Wave Lithotripsy combined with Tamsulosin Therapy will be given to the patients

Locations
Country Name City State
Pakistan services Institute of Medical Sciences Lahore Punjab

Sponsors (1)
Lead Sponsor Collaborator
Services Hospital, Lahore

Country where clinical trial is conducted

Pakistan, 

Outcome
Type Measure Description Time frame Safety issue
Primary stone clearance Number of patients cleared from ureteric stones 4 weeks
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