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Renal Insufficiency clinical trials

View clinical trials related to Renal Insufficiency.

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NCT ID: NCT00844662 Terminated - Clinical trials for Chronic Kidney Failure

Phase III Study to Investigate the Safety and Efficacy of Fermagate and Sevelamer Hydrochloride

Start date: July 2009
Phase: Phase 3
Study type: Interventional

Magnesium iron hydroxycarbonate is a phosphate binder that absorbs phosphate from food, reducing the amount that the body can absorb. The purpose of this study is to assess the efficacy of magnesium iron hydroxycarbonate in subjects requiring haemodialysis, compared with a marketed phosphate binder, sevelamer hydrochloride.

NCT ID: NCT00841126 Terminated - Clinical trials for Chronic Kidney Failure

Phase III Study to Investigate the Safety and Efficacy of Fermagate and Lanthanum Carbonate

Start date: July 2009
Phase: Phase 3
Study type: Interventional

Magnesium iron hydroxycarbonate is a phosphate binder that absorbs phosphate from food, reducing the amount that the body can absorb. The purpose of this study is to assess the efficacy of magnesium iron hydroxycarbonate in subjects requiring hemodialysis, compared with a marketed phosphate binder, lanthanum carbonate and placebo.

NCT ID: NCT00830791 Terminated - Type 2 Diabetes Clinical Trials

A Single Dose Study to Investigate the Pharmacokinetics of MK-0941 in Participants With Renal Insufficiency (MK-0941-015-02)

Start date: January 2009
Phase: Phase 1
Study type: Interventional

This study will assess the pharmacokinetics of MK-0941 in participants with varying degrees of renal insufficiency.

NCT ID: NCT00818701 Terminated - Clinical trials for Congestive Heart Failure

Study of Low Dose Nesiritide With or Without Sildenafil in Congestive Heart Failure Patients With Renal Dysfunction

BNP+PDEVI
Start date: February 2009
Phase: Phase 1
Study type: Interventional

The purpose of the study is to show that low dose recombinant BNP coupled with phosphodiesterase V inhibition will improve renal dysfunction and promote relief of volume overload in patinets with acute decompensated heart failure complicated by the cardiorenal syndrome.

NCT ID: NCT00816790 Terminated - Septic Shock Clinical Trials

Standard Vs Adjusted Dosing of Piperacillin/Tazobactam in Acute Renal Failure and Septic Shock

Start date: January 2009
Phase: Phase 4
Study type: Interventional

The objective of this study is to determine the feasibility of conducting a large scale randomized controlled trial comparing standard and renally adjusted dosage of antibiotics in the septic shock patients with acute renal dysfunction. We will use Piperacillin as the prototype antibiotic in our study.

NCT ID: NCT00793182 Terminated - Renal Impairment Clinical Trials

Effects of Contrast Media on Subjects With Stable Reduced Renal Function Undergoing Contrast-Enhanced Computed Tomography

CINOPSIS CT
Start date: January 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the contrast-induced nephropathy (CIN) rate in subjects randomized to receive either Ioversol or Iodixanol for contrast-enhanced computed tomography.

NCT ID: NCT00787618 Terminated - Renal Impairment Clinical Trials

Evaluate PK and Safety of Proellex® in Females With Various Stages of Impaired Renal Function and Healthy Females

Start date: October 2008
Phase: Phase 1/Phase 2
Study type: Interventional

PK and safety profile of Proellex® in females with various stages of impaired renal function

NCT ID: NCT00785772 Terminated - Renal Impairment Clinical Trials

A Post-Marketing Clinical Pharmacokinetics Study Of Gabapentin In Japanese Epileptic Subjects With Renal Impairment

Start date: March 2010
Phase: Phase 4
Study type: Interventional

The primary objectives of this study are to evaluate the pharmacokinetics (PK) following administration of gabapentin in Japanese epileptic patients with renal impairment to confirm if there are any clinically relevant differences between the plasma gabapentin concentration simulated by population PK model, which was used for the evidence of the dose adjustment for the patients with renal impairment, and observed plasma gabapentin concentration.

NCT ID: NCT00785551 Terminated - Healthy Clinical Trials

Comparative Study of Quinine Sulfate in Healthy Patients and in Patients With Renal Impairment

Start date: November 2007
Phase: Phase 1
Study type: Interventional

The effects of mild or moderate renal impairment (creatinine clearance 30 to 50 ml/min or >50 to 80 ml/min, respectively) on the pharmacokinetic profile of quinine and its active metabolite, 3'-hydroxyquinine, will be investigated. Safety and tolerability in healthy subjects versus those with mild to moderate renal impairment will be compared, as well.

NCT ID: NCT00782639 Terminated - Diabetes Mellitus Clinical Trials

Renal Safety of Iopamidol Versus Iodixanol During Coronary Angiography in Diabetic Patients

RECARE
Start date: March 2009
Phase: Phase 4
Study type: Interventional

The purpose of this study is to compare the incidence of contrast-induced nephropathy (CIN) following the administration of iopamidol-370 (Iopamiro-370) and iodixanol-320 (Visipaque 320) in patients with moderate-to-severe chronic kidney disease and diabetes mellitus undergoing cardiac angiography.