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Effects of Levosimendan in Acute Kidney Injury After Cardiac Surgery — LEVOAKI  

Acute Kidney Injury Clinical Trial

Official title:
Effects of Levosimendan in Acute Kidney Injury After Cardiac Surgery

Clinical Trial Summary

Acute kidney injury (AKI) is a common complication after cardiac surgery. Mismatch in renal oxygen demand-supply may be an important pathogenetic factor. Levosimendan has been shown to improve renal blood flow, glomerular filtration rate and renal oxygenation in healthy controls after cardiac surgery. In order to investigate the effect of levosimendan in patients with AKI after cardiac surgery, the investigators plan a randomized placebo controlled trial. 30 patients will receive levosimendan or placebo. Renal blood flow and filtration fraction will be measured using infusion clearance technique of para-aminohippuric acid and Chromium ethylenediaminetetraacetic acid (Cr-EDTA) respectively.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02531724
Study type Interventional
Source Sahlgrenska University Hospital, Sweden
Contact
Status Completed
Phase Phase 4
Start date September 2015
Completion date December 2020
View Details
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