The Effect of Neuromuscular Electrical Stimulation (NMES) on the Renal Function and Renal Blood Flow

Renal Injury Clinical Trial

— NMES  

Official title:

The Effect of Neuromuscular Electrical Stimulation (NMES) on the Renal Function and Renal Blood Flow for Patients With Pregnancy Related- Acute Kidney Injury

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04580329
• Other study ID #: NMES
• Status: Recruiting
• Phase: N/A
• Start date: October 15, 2020
• Est. completion date: November 30, 2020

Study information

• Verified date: October 2020
• Source: Assiut University
• Contact: Ahmed T Ahmed, A professor
• Phone: 01062716629
• Email: talaat83[@]aun.edu.eg
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

A randomized prospective controlled study aims to evaluate the effect of neuromuscular electrical stimulation on the renal function and renal blood flow of post partum women with acute kidney injury.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: November 30, 2020
• Est. primary completion date: November 1, 2020
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 18 Years to 60 Years

Eligibility

Inclusion Criteria:

• Patients aged 18 or old and hemodynamically stable.

• Post-partum women who developed AKI.

Exclusion Criteria:

• Pregnant women .

• Patients who required any emergency or elective surgery during the study; those who presented acute heart or lung disease, skin rashes, tumors, infections, diabetes mellitus or hypoesthesia in the region that the neuromuscular electrical stimulation would be applied.

• Patients with a Pacemaker.

• Epileptic Patients.

• Patients with recent effects of stroke (less than 3 months).

• Uncontrolled hypertension (systolic blood pressure > 230 mm Hg and diastolic blood pressure > 120 mm Hg).

Related Conditions & MeSH terms

• Acute Kidney Injury
• Renal Injury
• Wounds and Injuries

Intervention

Procedure:
• neuromuscular electrical stimulation (NMES) in addition to routine hospital care
Patients in the NMES group will receive NMES sessions as the electrodes will be placed around the bilateral femoral quadriceps muscles and at the site of renal arteries. NMES(>100 Hz, 50-80 µ sec) will be performed for 55 min including 5 minutes for warm up and 5 minutes for recovery . The intensity of electrical stimulation will be adjusted to suit the comfort level of each individual patient without producing discomfort or pain.
• routine hospital care without NMES
routine hospital care include all the routine intervention done for post partum women with AKI including fluid resuscitation, diuretics, hemodialysis

Locations

Country	Name	City	State
Egypt	Ahmed Talaat Ahmed	Assiut
Egypt	Ahmed Talaat Ahmed	Assiut

Sponsors (1)

Lead Sponsor	Collaborator
Ahmed talaat ahmed aly

Country where clinical trial is conducted

Egypt, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	renal function change	serum creatinine level will be assessed and it will show improvement	for 7 days
Primary	renal blood flow change	urine output will be assessed and it will show improvement	for 7 days