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Multi-center Study to Transplant Hepatitis-C Infected Kidneys — MYTHIC  

Hepatitis C Clinical Trial

Official title:
A Multi-Center, Open-Label Study of Glecaprevir/Pibrentasvir to Treat Recipients of Transplanted Kidneys From Deceased Donors With Hepatitis C Virus

Clinical Trial Summary

Open label multi center study for the donation of HCV positive kidneys to HCV negative recipients with interventional treatment to prevent HCV transmission upon transplantation.

Clinical Trial Description

The study objective is to determine if the administration of the direct acting antiviral glecaprevir/pibrentasvir for 8 weeks after kidney transplantation is both safe and effective at preventing the spread of HCV infection from donor kidney with known HCV infection (all genotypes) to an HCV negative recipient as evidenced by a negative HCV viral RNA at 12 weeks post treatment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03781726
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Completed
Phase Phase 4
Start date April 10, 2019
Completion date December 31, 2021
View Details
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