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Remission clinical trials

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NCT ID: NCT04986124 Recruiting - Clinical trials for Major Depressive Disorder

Quality of Life in Chinese Working and School Age Population With MDD

Start date: April 1, 2021
Phase:
Study type: Observational [Patient Registry]

Major depressive disorder (MDD) is a common mental illness with high prevalence and global burden. Previous studies revealed that over 70% patients in remission still had decreased quality of life, severe function impairment, low positive mental health score and poor coping ability. However, few studies focus on working and school age patients with MDD. A GBD survey showed that over 40% MDD patients are 15-50 years old. Therefore, we initiate the present multi-center cross-sectional survey to investigate the associations between clinical symptoms, cognitive function, occupational/study ability, and quality of life in Chinese working and school age population with MDD who are in remission.

NCT ID: NCT04916249 Active, not recruiting - Cancer Clinical Trials

Testing an Herbal Pain Relief Patch to Reduce Pain in Cancer Survivors

Start date: May 28, 2021
Phase: Phase 2
Study type: Interventional

The purpose of this study is to find out whether Tibetree Pain Relieving Plaster, an herbal pain relief patch, may be able to reduce this pain. Tibetree Pain Relieving Plaster is available as an over-the-counter (non-prescription) treatment for the temporary relief of minor aches and pains in muscles and joints. This study is the first to test this treatment in people who have had cancer.

NCT ID: NCT03831750 Completed - Clinical trials for Inflammatory Bowel Diseases

Assessing the Effectiveness of a Stress Reduction Intervention in Inflammatory Bowel Disease (IBD)

Start date: February 22, 2019
Phase: N/A
Study type: Interventional

The investigators have designed a guided, online, tri-component, stress reduction intervention for participants with inflammatory bowel diseases.

NCT ID: NCT03574948 Completed - Ulcerative Colitis Clinical Trials

5-HTP in Patients With IBD in Clinical and Biologic Remission:Effect on Fatigue Scores

TRP-IBD
Start date: December 6, 2018
Phase: Phase 2
Study type: Interventional

This placebo cross-over trial aims to study the effect of the oral intake of an essential amino-acid 5-OH tryptophan, the precursor of serotonin, on the fatigue scores in IBD patients in deep clinical and biological remission.

NCT ID: NCT03518814 Completed - Remission Clinical Trials

Quality of Life in Patients With Multimetastatic Melanoma Currently in Remission (QUALM)

QUALM
Start date: April 9, 2018
Phase:
Study type: Observational

Few studies have been conducted on the quality of life of patients with stage IV melanoma. Particularly, there is no data regarding the quality of life of patients with a multimetastatic melanoma currently in remission. Then, the main objective of this study is to evaluate the quality of life from a point of view medico-psycho-social in patients with multimetastatic melanoma in remission for more than 6 months.

NCT ID: NCT03261206 Active, not recruiting - Crohn Disease Clinical Trials

Stopping Aminosalicylate Therapy in Inactive Crohn's Disease

STATIC
Start date: November 20, 2017
Phase: Phase 4
Study type: Interventional

The purpose of this study is to assess whether withdrawal of aminosalicylate (5-ASA) is non-inferior to continuation of 5-ASA therapy in Crohn's disease (CD) subjects in remission.

NCT ID: NCT03248180 Recruiting - Psychosis Clinical Trials

Guided Dose Reduction of Antipsychotic in Patients With Psychosis in Remitted States

GDR
Start date: July 24, 2017
Phase: N/A
Study type: Observational

A 2-year prospective observational study comparing a group of patients in remitted states of psychosis undergoing guided antipsychotic dose reduction to a similar group of patients under maintenance antipsychotic treatment with the main outcome of interest that if the rates of relapse of psychosis between these two groups will be different.

NCT ID: NCT03176875 Recruiting - Crohn Disease Clinical Trials

Comparison of Partial and Exclusive Enteral Nutrition in the Treatment of Active Childhood-onset Crohn's Disease

Start date: May 25, 2017
Phase: N/A
Study type: Interventional

The primary objective of this study is to determine the efficacy of a novel enteral nutrition (EN) protocol (delivering 75% of patient's caloric needs through EN) for induction of remission in patients with active childhood-onset Crohn's disease (CD) and compare it to the standard protocol with exclusive enteral nutrition (EEN). This novel approach allows patients to consume remaining calories (25%) from an antiinflammatory diet for CD (AID-CD). The hypothesis is that no significant difference in the remission rate between the novel EN protocol with partial enteral nutrition (PEN) and standard protocol with EEN will be observed.

NCT ID: NCT03123640 Completed - Clinical trials for Drug-Related Side Effects and Adverse Reactions

Improving Drug Safety in Emergency Patients -a Randomized Controlled Trial

EPIMERR
Start date: April 24, 2017
Phase: N/A
Study type: Interventional

Aim/Objective: Investigate the effect of implementing a working model for performing medication reconciliation (MR) and medication review (MRe) in the emergency department (ED), on readmissions, patient safety and efficiency of the stay in the ED and the hospital. Research design: randomized, controlled, non-blinded trial. Control group; standard care. Intervention group; MR and MRe performed at admission to the ED by a clinical pharmacist in the interdisciplinary team. The intervention is based on a working model for MR, developed in our initiation project, and it will be adapted to also include MRe. Key challenges in this research field: Currently no implemented systematic model ensuring that the patient's correct medication list is obtained and assessed at the point of admission. There is lack of studies investigating the clinically outcome of performing MR and MRe in the ED. Lack of knowledge on the extent of drug related hospital admissions in Norway. These challenges are also recognized and prioritized by the Norwegian authorities. Impact and utility: The results from this study will give important answers to the challenges listed above. The results could imply a huge impact on how to organize ED in Norway regarding drug safety. If the hypothesis of this study is confirmed, implementing the intervention described will increase patient safety, both the hospital and society can reduce health care expenses from readmissions, and also the readmission-burden can be reduced for the patients.

NCT ID: NCT03037190 Recruiting - Clinical trials for Diabetes Mellitus, Type 1

Preservation of Residual Beta Cell Mass and Prevention of Celiac Disease in Children With Recent Onset Type 1 Diabetes

Diabglut
Start date: December 2015
Phase: N/A
Study type: Interventional

The overall aim of this project is to investigate whether a gluten free diet after the onset of type 1 diabetes (T1D) can better preserve the remaining beta cell mass and at the same time prevent the development of Celiac Disease (CD) in these patients. Specific aims • To study whether gluten free diet during one year after the onset of diabetes influence the appearance and duration of clinical remission in children with Type 1 diabetes. New data show that a gluten free diet is beneficial concerning the insulin production after the onset of diabetes. The investigators want to investigate if gluten is a triggering protein for the destruction of the beta cell function after the onset of diabetes by comparing children who have a normal diet compared to children with a gluten free diet during one year after the onset of the disease. - To study whether a gluten free diet during one year after the onset of diabetes prevent the development of Celiac Disease in these children and the impact of having two diseases It is known that it is almost 10 times more common that children with Type 1 Diabetes (IDDM) develop Celiac Disease (CD) than the general population and that most of these children (6-7 %) develop CD after the onset of Diabetes and within 5 years. Based on our new data that CD is preventable to some extent the investigators plan to perform randomized controlled studies if it is possible to prevent or postpone CD by means after the onset of IDDM. - To investigate the impact of gluten free diet on the regulation of autoimmune responses The investigators will test the hypothesis that gluten free diet in children with recent onset T1D will implement immune regulation and inhibit the activation of potentially autoreactive T cells.