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Remifentanil clinical trials

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NCT ID: NCT03901716 Completed - Bronchoscopy Clinical Trials

Comparison of Sufentanil, Fentanyl and Remifentanil in Combination With Midazolam During Bronchoscopy Under Conscious Sedation

Start date: January 15, 2019
Phase: Phase 4
Study type: Interventional

The best opioid for bronchoscopy is still unclear.This randomized double-blind prospective study was conducted on a total of 60 patients who were randomly allocated into 3 groups: Group S received sufentanil 0.1 mcg/kg, Group F received fentanyl 1 mcg/kg and Group R received remifentanil target-controlled infusion with effect-site target concentration of 1ng/ml. Patients in all groups received midazolam to achieve moderate levels of sedation as assessed by the Narcotrend (NT; between B1 and C2). Adverse events, patient tolerance and physician satisfaction were analized.

NCT ID: NCT03817359 Completed - Propofol Clinical Trials

Use of a Remifentanil-propofol Mixture in Patients Undergoing Breast Cancer Surgery

Start date: August 3, 2018
Phase: N/A
Study type: Interventional

Co-administration of propofol and remifentanil is considered to be an ideal total intravenous anesthesia technique, which is widely used in induction and maintenance of general anesthesia. Remifentanil and propofol can be mixed in polypropylene syringes for one hour with a remaining concentration of 91% in small concentrations of remifentanil. However, delivery of remifentanil-propofol mixture by target-controlled infusion(TCI) for general anesthesia in surgical procedure has not been described. Breast cancer surgery ( including modified radical mastectomy and breast-conserving surgery) is a less time-consuming procedure for patients with breast cancer with one-hour duration in our hospital. This pilot study was to examine the merit of remifentanil-propofol mixture as a GA regimen for breast cancer surgery.

NCT ID: NCT03568396 Completed - Opioid Use Clinical Trials

Validation of Pupillary Response to Nociceptive Stimulation in Cardiac Surgery During Extracorporeal Circulation Period

DOLOCEC
Start date: August 22, 2018
Phase:
Study type: Observational

The relationship between the target effect site concentration of remifentanil and the pupil diameter and reactivity in response to a standard noxious stimulus in cardiac surgery during extra corporeal circulation will be evaluated.

NCT ID: NCT02243254 Completed - Pain, Postoperative Clinical Trials

Prevention of Remifentanil-induced Postoperative Hyperalgesia With Intravenous Ibuprofen

Start date: July 2014
Phase: N/A
Study type: Interventional

Postoperative hyperalgesia has been reported after intraoperative administration of small or high-dose remifentanil. Cyclooxygenase inhibitor exhibit preventive effects on the development of opioid-induced hyperalgesia. The aim of this study is to evaluate the preventive effect of intravenous ibuprofen (Caldolor®) on remifentanil-induced hyperalgesia

NCT ID: NCT02031016 Completed - Chronic Pain Clinical Trials

Remifentanil vs Fentanyl During Cardiac Surgery and Chronic Thoracic Pain

REFLECT
Start date: February 2014
Phase: Phase 4
Study type: Interventional

This study will investigate the influence of intra-operative use of remifentanil versus fentanyl on the percentage of patients with chronic thoracic after cardiac surgery via sternotomy. Secondary quantitative sensory testing is performed to determine thermal and electrical detection and pain threshold and the difference in pain variability scoring. Postoperative pain scores, analgesic use, genetic variances and costs are measured.

NCT ID: NCT01572454 Completed - Dexmedetomidine Clinical Trials

Comparison of Dexmedetomidine and Remifentanil Infusion During CABG

Start date: March 2012
Phase: N/A
Study type: Interventional

We are trying to investigate whether intraoperative dexmedetomidine infusion could decrease the incidence of intraoperative hypokalemia and arrhythmia, and myocardial injury in patients undergoing off-pump coronary artery bypass graft, and trying compare these effects with those of remifentanil infusion.

NCT ID: NCT00763789 Recruiting - Conscious Sedation Clinical Trials

Local Anaesthesia and Remifentanil Sedation Versus Total Intravenous Anaesthesia for Hysteroscopic Surgery in an Ambulatory Surgery Department.

Start date: August 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to compare a new method: the combination of conscious sedation with remifentanil (a shortlasting opioid drug) and local anaesthesia, with the traditional general anaesthesia for hysteroscopic surgery. The primary outcomes are: the time spent in the operation room, the time to full mobilisation postoperatively and the time to complete recovery postoperatively and the time to discharge. Secondary outcome: patient satisfaction.