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Relative Bioavailability clinical trials

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NCT ID: NCT06025344 Not yet recruiting - Clinical trials for Relative Bioavailability

A Relative Bioavailability Study With a Novel PanCytoVirâ„¢ Oral Suspension (100 mg/ml)

Start date: June 2024
Phase: Phase 1
Study type: Interventional

An open-label, balanced, randomized, two-treatment, two-sequence, two-period, crossover, single dose oral relative bioavailability study of a novel PanCytoVirâ„¢ oral suspension (100 mg/mL) versus probenecid 500 mg tablets in normal healthy, adult, human subjects under fasting conditions.

NCT ID: NCT06025318 Not yet recruiting - Clinical trials for Relative Bioavailability

An Evaluation of the Effect of Food on the PK of a Novel PanCytoVirâ„¢ Suspension (100mg/ml), in Healthy, Adult Volunteers

Start date: June 2024
Phase: Phase 1
Study type: Interventional

This is an open-label, balanced, randomized, two-period, crossover, single dose study to compare the relative bioavailability in normal healthy, adult, human subjects under Fed and Fasting conditions. Subjects will receive a single oral dose of probenecid oral suspension (100 mg/mL) under fed and fasted conditions.

NCT ID: NCT05296382 Completed - Clinical trials for Relative Bioavailability

Bioavailability of Tebipenem (SPR994) Crushed Tablet

Start date: April 1, 2022
Phase: Phase 1
Study type: Interventional

The purpose of this study is to measure the amount of the antibiotic, tebipenem (SPR994) that is bioavailable after crushing the tablet and administering through a feeding tube with and without tube feeds.

NCT ID: NCT04814472 Completed - Clinical trials for Relative Bioavailability

Healthy Volunteer Study Comparing Tablet and Oral Solution Formulations

Start date: May 16, 2021
Phase: Phase 1
Study type: Interventional

A Two-Part, Open-Label, Crossover, Bioavailability Study Comparing Tablet and Oral Solution Formulations of BLD-0409 in Healthy Volunteers

NCT ID: NCT04686669 Completed - Clinical trials for Relative Bioavailability

A Relative Bioavailability Study of FOR-6219 in Capsule and Tablet Formulations

Start date: December 10, 2020
Phase: Phase 1
Study type: Interventional

This is a phase 1, randomised, open-label, three-way, three-period, crossover relative bioavailability study to assess the single-dose pharmacokinetics of FOR-6219 in capsule and tablet formulations in postmenopausal women. The effect of high-fat food on the pharmacokinetics of the tablet formulation will also be evaluated. A total of twelve, post-menopausal women, will be randomised to receive a single oral dose of FOR-6219 in three treatment periods: capsule formulation (fasted); tablet formulation (fed); tablet formulation (fasted)

NCT ID: NCT03934333 Completed - Clinical trials for Relative Bioavailability

A Study to Compare the Pharmacokinetics of Budesonide Delivered by PT027 Compared With Pulmicort Flexhaler (ELBRUS)

Start date: May 16, 2019
Phase: Phase 1
Study type: Interventional

This study is to compare the systemic exposure of budesonide delivered by the combination inhaler (budesonide/albuterol sulfate pressurized inhalation suspension [BDA metered dose inhaler {BDA MDI}]) with Pulmicort Flexhaler dry-powder inhaler (DPI).

NCT ID: NCT03483259 Completed - Clinical trials for Relative Bioavailability

To Explore the Pharmacokinetics and Relative Bioavailability of Sulfatinib Capsules in Two Different Manufacturers

CRC-C1721
Start date: April 2, 2018
Phase: Phase 1
Study type: Interventional

This is a single-center, randomized, open, single-dose, three-cycle cross-design study, which will be only enrolled Chinese male healthy volunteers.

NCT ID: NCT03154840 Active, not recruiting - Clinical trials for Relative Bioavailability

Relative Bioavailability Among Different Eutropin Formulations

Start date: May 31, 2017
Phase: Phase 1
Study type: Interventional

1. Compares and evaluates the relative bioavailability of single-dose subcutaneous administration of each of the Eutropin formulations to healthy male volunteers. 2. Ensure safety and tolerability of single, subcutaneous administration of Eutropin formulations to healthy male volunteers.

NCT ID: NCT02359045 Completed - Pharmacokinetics Clinical Trials

Study in Healthy Subjects to Compare the Concentrations of the Omega-3 Fatty Acids EPA and DHA in Blood When Delivered as Three New Capsules in Relation to the Epanova® Capsule Under Fasting and Fed Conditions

Start date: February 2015
Phase: Phase 1
Study type: Interventional

This study is a randomized, open-label, cross-over study in healthy subjects performed at a single study center. The study is divided into two parts, Part 1 and Part 2. The purpose of the study is to compare the pharmacokinetics (PK) of three different prototype capsule formulations (omega-3-carboxylic acids test formulations) with Epanova® capsules 1000 mg under fasted conditions in Part 1 and under fed conditions in Part 2. The results will be used as basis for choice of formulation for further pharmaceutical development.

NCT ID: NCT02052349 Completed - Clinical trials for Relative Bioavailability

Bioavailability of ABT-333 Within the Gastrointestinal Tract in Healthy Subjects

Start date: November 2013
Phase: Phase 1
Study type: Interventional

This open label, Phase 1 study is to investigate the relative bioavailability of ABT-333 when delivered within different sites of the gastrointestinal tract in 12 healthy subjects.