Retrospective Evaluation of Effect of Anterior Iliac Block

Regional Anesthesia Clinical Trial

Official title:

Retrospective Evaluation of Postoperative Analgesia Efficacy of the Anterior Iliac Block in Anterior Iliac Crest Bone Graft Harvesting: Preliminary Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06295224
• Other study ID #: GOKAEK-2024/02.19
• Status: Recruiting
• Start date: January 1, 2024
• Est. completion date: March 15, 2024

Study information

• Verified date: March 2024
• Source: Kocaeli University
• Contact: Hadi Ufuk Yörükoglu
• Phone: +902623038248
• Email: ufukyorukoglu[@]gmail.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In this study, the investigators aimed to evaluate the effect of ultrasound-guided anterior iliac block which was performed preoperatively. Anterior iliac bone harvesting is associated with severe postoperative pain. As several fascial plane blocks were defined to provide analgesia, their effects are debatable and requires high volumes of local anesthetic considering the regional anesthesia technique used for the main surgical procedure.

Description:

Autologous bone grafting is the method called the gold standard in the reconstruction of bone defects and nonunions. Anterior iliac crest is most frequently preferred as the source of autologous bone graft. However, severe pain after anterior iliac crest graft harvesting increases morbidity. Various regional anesthesia techniques have been defined for the purpose of postoperative analgesia. The mechanism of fascial plane blocks, one of these techniques, has not been fully elucidated and drug distribution varies from person to person. Postoperative analgesia of the iliac crest donor site can be achieved by i infiltration of local anesthetics or morphine. Single injection or continuous infusions of local anesthetic have proven effective in adults.

In this study; the investigators aimed to retrospectively scan the records of patients who received anterior iliac bone graft in our clinic and determine the postoperative analgesia effectiveness of anterior iliac block. The data obtained after the research will make a significant contribution to the literature in the postoperative analgesia management of patients who are planned to receive anterior iliac bone graft.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 14
• Est. completion date: March 15, 2024
• Est. primary completion date: March 10, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 70 Years

Eligibility

Inclusion Criteria:

• ASA-1, ASA-2 and ASA-3 patients

• Female/male

Exclusion Criteria:

• Anticoagulant drug use

• Known allergy to the medications to be used

• Infection in the area where the needle will be inserted

• Missing data

Related Conditions & MeSH terms

• Regional Anesthesia

Locations

Country	Name	City	State
Turkey	Kocaeli Universty	Kocaeli

Sponsors (1)

Lead Sponsor	Collaborator
Kocaeli University

Country where clinical trial is conducted

Turkey, 

References & Publications (7)

Black ND, Malhas L, Jin R, Bhatia A, Chan VWS, Chin KJ. The analgesic efficacy of the transversalis fascia plane block in iliac crest bone graft harvesting: a randomized controlled trial. Korean J Anesthesiol. 2019 Aug;72(4):336-343. doi: 10.4097/kja.d.18.00352. Epub 2019 Mar 19. — View Citation

Chin KJ, McDonnell JG, Carvalho B, Sharkey A, Pawa A, Gadsden J. Essentials of Our Current Understanding: Abdominal Wall Blocks. Reg Anesth Pain Med. 2017 Mar/Apr;42(2):133-183. doi: 10.1097/AAP.0000000000000545. — View Citation

Gundes H, Kilickan L, Gurkan Y, Sarlak A, Toker K. Short- and long-term effects of regional application of morphine and bupivacaine on the iliac crest donor site. Acta Orthop Belg. 2000 Oct;66(4):341-4. — View Citation

Morgan SJ, Jeray KJ, Saliman LH, Miller HJ, Williams AE, Tanner SL, Smith WR, Broderick JS. Continuous infusion of local anesthetic at iliac crest bone-graft sites for postoperative pain relief. A randomized, double-blind study. J Bone Joint Surg Am. 2006 Dec;88(12):2606-12. doi: 10.2106/JBJS.E.00984. — View Citation

Ouaki J, Dadure C, Bringuier S, Raux O, Rochette A, Captier G, Capdevila X. Continuous infusion of ropivacaine: an optimal postoperative analgesia regimen for iliac crest bone graft in children. Paediatr Anaesth. 2009 Sep;19(9):887-91. doi: 10.1111/j.1460-9592.2009.03095.x. — View Citation

Shin SR, Tornetta P 3rd. Donor Site Morbidity After Anterior Iliac Bone Graft Harvesting. J Orthop Trauma. 2016 Jun;30(6):340-3. doi: 10.1097/BOT.0000000000000551. — View Citation

Sondekoppam RV, Ip V, Johnston DF, Uppal V, Johnson M, Ganapathy S, Tsui BCH. Ultrasound-guided lateral-medial transmuscular quadratus lumborum block for analgesia following anterior iliac crest bone graft harvesting: a clinical and anatomical study. Can J Anaesth. 2018 Feb;65(2):178-187. doi: 10.1007/s12630-017-1021-y. Epub 2017 Nov 21. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Morphine consumption	Morphine consumption with patient controlled analgesia device	postoperative 1st hour, 6th hour, 12th hour and 24th hour
Secondary	NRS score	NRS score at rest	postoperative 1st hour, 6th hour, 12th hour and 24th hour