Clinical Study on the Safety and Effectiveness of Vagus Nerve Stimulation in the Treatment of Refractory Depression

Refractory Depression Clinical Trial

Official title: Clinical Study on the Safety and Effectiveness of Vagus Nerve Stimulation in the Treatment of Refractory Depression

Status Recruiting

Clinical Trial Summary

Based on the mechanism hypothesis and clinical efficacy of VNS in treating refractory depression, this study will evaluate the safety and efficacy of VNS in treating refractory depression through a small sample of clinical trials

Clinical Trial Description

This clinical trial is a prospective, self - controlled clinical validation study. Subjects who met the inclusion criteria and did not meet the exclusion criteria were screened to enter the test. After admission, subjects received vagus nerve stimulation and conventional treatment. Enrolled 10 subjects. Parameter setting and observation were performed 2 weeks after implantation of the vagus nerve stimulation lead and pulse generator, and follow-up evaluation was performed at 3, 6 and 12 months. ;

Related Conditions & MeSH terms

• Depression
• Depressive Disorder
• Depressive Disorder, Treatment-Resistant
• Refractory Depression

• NCT number: NCT04153812
• Study type: Interventional
• Source: Xijing Hospital
• Contact: Wang Huaning
• Phone: 13609161341
• Email: xskzhu@fmmu.edu.cn
• Status: Recruiting
• Phase: Phase 1/Phase 2
• Start date: November 1, 2019
• Completion date: May 30, 2022