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Reflex Sympathetic Dystrophy clinical trials

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NCT ID: NCT01118715 Terminated - Edema Clinical Trials

Use of Compression Glove to Prevent Complications After Distal Radius Fractures: a Randomized Controlled Trial

Start date: April 2010
Phase: N/A
Study type: Interventional

Distal radius fractures (DRF) are the most common type of fracture in the human body, and a large proportion of DRFs result in complications. Previously proposed preventive strategies have questionable efficacy and may impose additional risks on the patient. Because many complications secondary to distal radius fractures are associated with excessive swelling, a prophylactic means for edema reduction could dramatically reduce morbidity among this population. A compression glove is a non-invasive, non-pharmacological way to reduce edema. Previous studies have confirmed its utility in edema reduction after hand trauma and among patients with chronic inflammatory conditions, but none have sufficiently investigated the application to patients with distal radius fractures, a population in which this intervention could have a large impact. The investigators propose a randomized controlled trial to evaluate use of a compression glove during recovery among patients who have sustained an unstable distal radius fracture. The investigators hypothesize that patients who wear a compression glove after a distal radius fracture: - Will experience less edema - Will demonstrate greater functionality - Will recover more quickly - Will have lower incidence rates of carpal tunnel syndrome - Will have lower incidence rates of complex regional pain syndrome

NCT ID: NCT01037088 Completed - Multiple Sclerosis Clinical Trials

Effects of Vaporized Marijuana on Neuropathic Pain

Start date: December 2009
Phase: Phase 1/Phase 2
Study type: Interventional

This study theorized that a low dose of vaporized cannabis could alleviate nerve injury pain.

NCT ID: NCT01008553 Completed - Postoperative Pain Clinical Trials

A Confirmatory Study of Fentanyl in Participants With Post-herpetic Neuralgia, Complex Regional Pain Syndrome or Postoperative Pain Syndrome

Start date: December 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety of fentanyl in opioid-naive participants with post-herpetic neuralgia, complex regional pain syndrome or post-operative pain syndrome who cannot obtain a sufficient analgesic effect by the treatment of non-opioid analgesics (drug used to control pain).

NCT ID: NCT00949065 Withdrawn - Clinical trials for Complex Regional Pain Syndrome Type 1

Intravenous Immunoglobulins in Complex-regional Pain Syndrome

PAINLESS
Start date: August 2009
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether intravenous immunoglobulins are effective in the treatment of complex-regional pain syndrome.

NCT ID: NCT00904202 Completed - Clinical trials for Carpal Tunnel Syndrome

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

Start date: January 2003
Phase: Phase 4
Study type: Interventional

Patients with postherpetic neuralgia (PHN), diabetic neuropathy (DN), complex regional pain syndrome (CRPS), carpal tunnel syndrome, HIV neuropathy, idiopathic sensory neuropathy, or other peripheral neuropathy participated in a Phase IV clinical trial to assess the comparative efficacy and safety of Lidoderm monotherapy versus gabapentin monotherapy in treating a diverse group of peripheral neuropathic pain patients.

NCT ID: NCT00891397 Terminated - Clinical trials for Complex Regional Pain Syndromes

Pregabalin Versus Placebo as an Add on for Complex Regional Pain Syndrome (CPRS) of the Upper Limb Managed by Stellate Ganglion Block (The PREGA Study)

PREGA
Start date: November 2007
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the efficacy of pregabalin in patients with complex regional pain syndrome Type I and to determine whether it provides clinically significant pain relief and whether it improves functioning of the upper limb.

NCT ID: NCT00817128 Completed - Clinical trials for Complex Regional Pain Syndrome, Type I

Pain Exposure Physical Therapy (PEPT) Versus CBO in Patients With Complex Regional Pain Syndrome Type I (CRPS-1)

PEPTOC
Start date: January 2009
Phase: Phase 2/Phase 3
Study type: Interventional

The current Dutch CBO guideline treatment of Complex Regional Pain Syndrome Type I (CRPS-1) is very disappointing with chronification, disability and subsequent high medical costs and personal suffering. A possible better treatment is intensive function-oriented physical therapy or Pain Exposure in Physical Therapy (PEPT). However, there are no adequate studies performed that demonstrate the efficacy of PEPT and therefore PEPT is lacking in the Dutch CBO CRPS-1 guidelines. Despite a lacking scientific argumentation, the PEPT approach or Macedonian therapy, is now being adopted on a large scale among physical therapists in The Netherlands. There are two level C retrospective cohort studies demonstrating a promising and clinical relevant beneficial effect on pain and function after PEPT. In response to the growing demand for scientific argumentation among doctors and physical therapists with respect to the efficacy of PEPT, we conducted a pilot study at the UMC St Radboud Nijmegen. The results of this pilot study were very promising and therefore, we decided to design a large RCT to investigate the treatment effects and costs in CRPS patients treated with PEPT compared to CRPS patients treated with usual therapy according to the Dutch CBO guidelines.

NCT ID: NCT00815932 Withdrawn - Clinical trials for Diabetic Neuropathies

The Effect of Transcranial Direct Current Stimulation (t-DCS) On the P300 Component of Event-Related Potentials in Patients With Chronic Neuropathic Pain Due To CRPS or Diabetic Neuropathy

Start date: September 2016
Phase: N/A
Study type: Interventional

This is a controlled trial designed to determine short- and long-term effects of repeated tDCS on the P300 component of event-related evoked potentials in patients with chronic neuropathic pain due to Complex regional Pain Syndrome (CRPS) or diabetic neuropathy as compared with healthy subjects.

NCT ID: NCT00780390 Terminated - Clinical trials for Complex Regional Pain Syndrome

Autonomic Dysfunction and Spinal Cord Stimulation in Complex Regional Pain Syndrome

CRPS
Start date: January 2008
Phase: N/A
Study type: Interventional

To demonstrate that spinal cord stimulator has an effect on sympathetic function (the one that give us the fight and flight response). Therefore, if the spinal cord stimulator has an effect on sympathetic function, the responses from CRPS patients to different stimuli will differ significantly pre and post SCS implant. If CRPS patients exhibit autonomic, CRPS patients could be stratified according to their sympathetic function pre-implant. It is expected that patients with a moderate/mild form of autonomic dysfunction will have better outcomes with the SCS.

NCT ID: NCT00689585 Terminated - Clinical trials for Complex Regional Pain Syndromes

Safety and Efficacy Study of Ethosuximide for the Treatment of Complex Regional Pain Syndrome (CRPS)

Start date: September 2008
Phase: Phase 2
Study type: Interventional

Pain remains the most debilitating symptom for adult patients suffering from complex regional pain syndrome (CRPS). Most CRPS patients gain little to no relief from current painkillers. The purpose of this study is to evaluate the efficacy and safety of ethosuximide in search of much-needed adjunctive therapy to relieve the pain and suffering associated with CRPS.