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Rectal Prolapse clinical trials

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NCT ID: NCT06455501 Not yet recruiting - Rectal Prolapse Clinical Trials

FOAM: Functional Outcome After Ventral Mesh Rectopexy

Start date: September 1, 2024
Phase:
Study type: Observational

Rectal prolapse is a protrusion of rectal wall through the anus. A surgical technique called Ventral mesh rectopexy has become a standard procedure for this condition in many centers. The goal of this trial is to investigate functional outcome, recurrence rates and complications after ventral mesh rectopexy. The main question it aims to answer is: - Do bowel function, quality of life and sexual function improve after Ventral mesh rectopexy? Participants will: - be asked to fill in questionaires before surgery, 3-6 months after surgery and 12 months after surgery. - be examined by a surgeon 3-6 months, 12 months and 3 years after surgery.

NCT ID: NCT06353230 Completed - Rectal Prolapse Clinical Trials

Comparison of Sclerotherapy Agents Used for Rectal Prolapse Treatment in Children

Prolapse
Start date: October 15, 2019
Phase: N/A
Study type: Interventional

Introduction Patients with rectal prolapse are treated with injection sclerotherapy, which is the most often used first-line surgical technique. Injection sclerotherapy has a success rate of 90-100% in youngsters, according to certain studies. Objective To compare the outcome of injection sclerotherapy using 5% Phenol in almond oil, 15% hypertonic saline and 50% dextrose water in the treatment of rectal prolapse in children.

NCT ID: NCT06330857 Active, not recruiting - Fecal Incontinence Clinical Trials

Recurrence and Bowel Function After Laparoscopic Vaginorectopexy, a Modified Anterior Rectopexy

Start date: May 28, 2002
Phase: N/A
Study type: Interventional

Several pelvic prolapses can render defecation difficulties and they are often treated with different surgical techniques. This study will evaluate a novel variation of a laparoscopic technique used to treat rectal prolapse that is modified to treat multiple pelvic prolapses. 25 women with symptoms of obstructed defecation and multiple pelvic prolapses are assessed before and after surgery with clinical examination, defecography and a questionnaire for bowel function and quality of life. Follow up was scheduled after three and twelve months and at long term (minimum ten years).

NCT ID: NCT06245577 Recruiting - Clinical trials for Pelvic Organ Prolapse

Biological Mesh Versus Synthetic Mesh in Interdisciplinary RRP With SCP

BioSynIRS
Start date: January 30, 2024
Phase: N/A
Study type: Interventional

The purpose of the pilot study is to demonstrate the safety and efficacy of a biological mesh compared to a standard synthetic mesh for the planned procedure in the above-mentioned clinical picture. Subsequently, a multicentre, randomized intervention study is planned to confirm the results and evaluate the long-term outcomes.

NCT ID: NCT06174584 Completed - Rectal Prolapse Clinical Trials

Comparison of Cow Milk and 15% Hypertonic Saline in the Treatment of Rectal Prolapse in Children

Start date: February 1, 2021
Phase: Early Phase 1
Study type: Interventional

To see the outcome of results of Cow Milk & Hypertonic Saline in the treatment of Rectal Prolapse in Children

NCT ID: NCT05918367 Recruiting - Surgery Clinical Trials

Multicenter Ventral Mesh Rectopexy Registry Collaborative

M2R2
Start date: September 25, 2023
Phase:
Study type: Observational [Patient Registry]

The goal of this multicenter observational study is to collect data prospectively of patients with pelvic organ prolapse undergoing ventral mesh rectopexy (as well as rectoceles, entero-/sigmoidoceles/ intussusception/ rectal prolapse or combined) by laparoscopy or robotic surgery and to evaluate the longterm functional outcomes. Secondly complications (mesh erosions, recurrence, reoperations) are evaluated. Following main questions will be analysed - other can follow in consultation with the collaborative 1. Is VMR the technique of choice for treatment of rectoceles? Functional results - recurrence - mesh related complications 2. Has a perineal descent an impact on the functional outcome of ventral mesh rectopexy perfored for external rectal prolaps, internal rectal prolaps, rectocele, enterocele, sigmoidcele or combined pelvic organ prolapse?

NCT ID: NCT05915936 Completed - Rectal Prolapse Clinical Trials

LVMR Versus PSR for External FTRPin Elderly Patients

Start date: April 1, 2012
Phase:
Study type: Observational

In frail patients with external full-thickness rectal prolapse (FTRP), the exact postoperative recurrence and functional result outcomes difference between Laparoscopic ventral mesh rectopexy (LVMR) and perineal stapler resection (PSR) have not been investigated, leading to ineffective treatment. Objectives: Evaluating the efficacy of PSR versus LVMR for treating external FTRP in the elderly. Design: This was a retrospective study that involved multiple centers. Settings: This study was conducted in the colorectal surgical units of our Universities' Hospitals Patients: 330 elderly patients divided into LVMR group (250), and PSR (80) between April 2012 and April 2019. Before and after surgery, patients were evaluated using the Wexner Incontinence Scale, the Altomare Constipation Scale, and the patient's satisfaction. Main outcomes measurement: The primary outcome was the recurrence rate and risk factors of FTRP. Secondary outcomes were postoperative incontinence and constipation and patients' satisfaction.

NCT ID: NCT05728554 Enrolling by invitation - Rectal Prolapse Clinical Trials

Breakthrough Improvement Collaborative for Ventral Mesh Rectopexy

BIC4VMR
Start date: March 1, 2023
Phase:
Study type: Observational

Different studies showed large variation between care processes in multiple diseases, this leads to large variation in outcomes. Better adherence to evidence-based guidelines for these diseases can reduce this variation and can improve the health outcomes. Ventral mesh rectopexy has gained popularity in Europe to treat different rectal prolapse syndromes. This procedure has been shown to achieve acceptable anatomic results with low recurrence rates, few complications, and improvements of both constipation and fecal incontinence. However, there is limited data on the care process and outcomes. Moreover, there is no insight in the variation between different centers for patients undergoing ventral mesh rectopexy. This study aims to map the variation in care for patients undergoing ventral mesh rectopexy in Flemish hospitals and to get an overview about the variation within and between these hospitals. Hereby, this will be a repeat of the studies for colorectal cancer, fragility hip fractures, stroke and breast cancer surgery.

NCT ID: NCT05569980 Enrolling by invitation - Quality of Life Clinical Trials

The Nordic Rectal Prolapse Study

NORDIC
Start date: April 1, 2023
Phase:
Study type: Observational

The goal of this observational study is to gather data about surgical procedures for rectal prolapse in adult human subjects. The main question it aims to answer is: • Which procedure is best for treating external rectal prolapse? Participants will: - be included if they can consent to participation - be offered standard care treatment, as no interventions will be done - be asked to answer relevant questionnaires within 3 months prior to the surgery for rectal prolapse - be asked to answer the same questionnaires 6 and 12 months postoperative - optionally answer the questionnaires again at 3 and 1 year postoperative, but this is not part of the existing funding body

NCT ID: NCT05321134 Recruiting - Colo-rectal Cancer Clinical Trials

Evaluation of SINGLE PORT (SP) Robotic Technology in Colorectal Surgery

Start date: April 28, 2022
Phase: N/A
Study type: Interventional

Currently a multiport robotic surgery platform (Intuitive Xi) is widely available and used for colorectal surgery indications. A Single port platform (Intuitive SP) is FDA approved for Head and Neck and Urology but has not been widely used in colorectal surgery. This study seeks to evaluate the safe and effective use of the SP platform for colorectal surgery indications.