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Reconstructive Surgery clinical trials

View clinical trials related to Reconstructive Surgery.

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NCT ID: NCT05267197 Completed - Telemedicine Clinical Trials

3D Telemedicine: A Clinician Feedback Study

Start date: November 11, 2020
Study type: Observational

The use of Telemedicine has increased significantly due to constraints imposed by the Covid pandemic. 3D telemedicine uses multiple cameras in the clinic room which can reconstruct an image in 3 dimensions in real-time, which may be beneficial in more visual focused specialties such as Plastic Surgery. There are no clinical data regarding the use of 3D telemedicine, with previous studies laboratory based without clinicians or patients. This study aims to provide clinician data comparing 3D and 2D Telemedicine, and feedback to allow incremental improvement of the system prior to clinical trials involving patients.

NCT ID: NCT05032768 Recruiting - Breast Cancer Clinical Trials

The Association Between Radiation Dermatitis and Skin Microbiome in Breast Cancer Patients

Start date: January 1, 2021
Study type: Observational

The breast cancer patients who received radiotherapy after mastectomy and breast reconstruction will be enrolled. The skin microbiome before radiotherapy and its changes after radiotherapy will be analyzed systematically to find out whether the skin microbiome is associated with the severity of radiation dermatitis.

NCT ID: NCT04261829 Recruiting - Breast Cancer Clinical Trials

AFT: Introduction of a Full Breast Reconstructive Method

Start date: December 9, 2020
Study type: Observational

A multicentre prospective cohort study will monitor the efficacy and safety of Autologous Fat Transfer (AFT) with pre-expansion. AFT will be evaluated in terms of quality of life, aesthetic result, complications, oncological safety and cost-effectiveness. It follows the BREAST trial, the randomised controlled trial comparing AFT with implant-based reconstruction. In this study, patients all receive AFT.

NCT ID: NCT04195854 Completed - Clinical trials for Reconstructive Surgery

STARS-R Registry: Retrospective Analysis of Poly-4-hydroxybutyrate (P4HB) Scaffold Use

Start date: December 17, 2019
Study type: Observational

This is a retrospective chart review performed at multiple clinics aimed at providing real-world evidence of the use and safety of the P4HB scaffold. Data on patient demographics, relevant medical history, product and procedure used, product safety, and outcome measures will be collected as available.

NCT ID: NCT04002713 Completed - Clinical trials for Head and Neck Cancer

Comparison of Choosing Free ALT or Free PMT for Reconstruction With Head and Neck Cancer

Start date: March 20, 2019
Study type: Observational

This study was designed to compare the outcome of the anteromedial thigh (AMT) and anterolateral thigh (ALT) flaps in head and neck cancer reconstruction.

NCT ID: NCT03899051 Recruiting - Clinical trials for Reconstructive Surgery

PRF and Connective Tissue Graft in Interdental Papilla Reconstruction

Start date: December 1, 2018
Phase: N/A
Study type: Interventional

Interdental papilla deficiency leads to food impaction, problems with phonetics and an unaesthetic appearance. Reconstruction of the deficient papilla is therefore, important. Perusal of available literature reveals only case reports and case series in the reconstruction of interdental papilla using subepithelial connective tissue graft and platelet rich fibrin autologous graft. Therefore, the current randomized controlled clinical study is intended to compare the effect of platelet rich fibrin and subepithelial connective tissue graft on interdental papilla reconstruction.

NCT ID: NCT03212365 Completed - Clinical trials for Venous Thromboembolism

Minimization of Bleeding Related Adverse Drug Events in Plastic & Reconstructive Surgery

Start date: July 3, 2017
Phase: Phase 2
Study type: Interventional

Plastic and reconstructive surgeons consistently create large, raw surfaces as part of their operative procedures. Thus, plastic & reconstructive surgery patients are among those at highest risk for anticoagulant-associated bleeding adverse drug events (ADEs). This study seeks to optimize both the safety and effectiveness of post-operative enoxaparin by comparing aFXa levels, bleeding events, and VTE events among plastic & reconstructive surgery patients randomized to receive two different enoxaparin dose regimens.

NCT ID: NCT02411292 Completed - Clinical trials for Venous Thromboembolism

Enoxaparin Metabolism in Reconstructive Surgery Patients

Start date: March 2015
Phase: Phase 2
Study type: Interventional

Venous thromboembolism (VTE) is a leading cause of death among hospitalized patients, and is an important patient safety issue in plastic surgery. Previous work has shown that enoxaparin prophylaxis can prevent many post-operative VTE events, and current American Society of Plastic Surgeons guidelines support enoxaparin prophylaxis for high-risk patients. Highest risk patients often have cancer or trauma reconstruction. Primary outcomes include 1) peak and trough steady-state aFXa levels in response to standard and escalated doses of enoxaparin and 2) the proportion of patients with appropriate aFXa levels pre and post initiation of a clinical protocol for enoxaparin dose adjustment. The investigators expect that standard dosing will result in inadequate aFXa peak and trough levels, and that the clinical dose adjustment protocol will significantly improve the proportion of in-range aFXa levels. The investigators will also develop a linear regression-based equation to calculate, based on patient-level factors, the required dose of enoxaparin to generate in-range aFXa levels. This research may show that the current "one size fits all" approach to enoxaparin prophylaxis is insufficient. In the trauma and orthopaedic populations, patients with low initial aFXa levels are significantly more likely to develop deep venous thrombosis. Thus, this study has important implications for appropriate enoxaparin dose magnitude and frequency, and may ultimately help to decrease the substantial morbidity and mortality associated with post-operative VTE.

NCT ID: NCT02089490 Not yet recruiting - Clinical trials for Reconstructive Surgery

Evaluation of NEVELIA® in Terms of Safety and Efficacy for Third-degree Burns Treatment or Reconstructive Surgery

Start date: April 2014
Phase: N/A
Study type: Interventional

The dermal substitute NEVELIA® has received CE marking in July 9, 2013. Its use in the NEVAL protocol will be in accordance with its leaflet, i.e. for the treatment of burns or in case of reconstructive plastic surgery. The matric implantation will be followed by autologous skin grafting when the neodermis formation will be observed.

NCT ID: NCT01681797 Terminated - Clinical trials for Reconstructive Surgery

Fluorescence Angiography: Planning and Monitoring of Perforator Flaps

Start date: August 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether fluorescence angiography is an effectiveness technique for the localization of vascular perforators and their area of perfusion and for the postoperative monitoring of flap perfusion.