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Ultra-hypofractioNated Adjuvant Radiotherapy ± sImultaneous Integrated Boost for Low-risk Breast Cancer Patients — UNIQUE  

Breast Cancer Clinical Trial

Official title:
Ultra-hypofractioNated Radiotherapy ± sImultaneous Integrated Boost for Low-risk(risQue) Breast Cancer Patients After Breast Conservative sUrgery or mastEctomy (UNIQUE)

Clinical Trial Summary

This is a phase II study to investigate the feasibility of Ultra-hypofractionated radiotherapy with or without simultaneous integrated boost for low risk breast cancer patients who have received breast conservative surgery of mastectomy.

Clinical Trial Description

During the study, the patients would undergo radiation of 5.2Gy for 5 fractions to the prophylactic radiation volumes and and a 6Gy per-fraction simultaneous boost to the tumor bed or other high-risk volumes. Acute toxicity of grade 2 or higher in the following 12 weeks after radiotherapy is the primary end point. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05762900
Study type Interventional
Source Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Contact Shu-Lian Wang, M.D.
Phone 8610-87788290
Email wangsl@cicams.ac.cn
Status Recruiting
Phase Phase 2
Start date October 25, 2022
Completion date October 25, 2030
View Details
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